C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

Last updated: April 4, 2025
Sponsor: Pharming Technologies B.V.
Overall Status: Completed

Phase

N/A

Condition

Allergy

Hereditary Angioedema

Allergies & Asthma

Treatment

rhC1INH or pdC1INH

Clinical Study ID

NCT01397864
C1 1412
  • All Genders

Study Summary

This is a non-interventional treatment Registry of Hereditary Angioedema (HAE) patients treated with C1 inhibitor, either plasma-derived (pdC1INH) or the recombinant human form (rhC1INH / Ruconest), to observe adverse events and insufficient efficacy, and to assess the immunological profile following single and repeated treatment with Ruconest.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Decision to treat the HAE patient with C1 inhibitor (either Ruconest or pdC1INH)

  • Patients must give written informed consent

Exclusion

Exclusion Criteria:

  • A diagnosis of acquired C1INH deficiency (AAE)

Study Design

Total Participants: 181
Treatment Group(s): 1
Primary Treatment: rhC1INH or pdC1INH
Phase:
Study Start date:
July 01, 2011
Estimated Completion Date:
December 10, 2024

Study Description

see below

Connect with a study center

  • UMHAT Alexandrovska EAD

    Sofia,
    Bulgaria

    Site Not Available

  • KBC Split

    Split,
    Croatia

    Site Not Available

  • CHC Sestre milosrdnice

    Zagreb,
    Croatia

    Site Not Available

  • General Hospital Sibenik

    Šibenik,
    Croatia

    Site Not Available

  • Faculty Hospital by St. Anna Brno

    Brno,
    Czech Republic

    Site Not Available

  • Faculty Hospital by St. Anna Brno

    Brno,
    Czechia

    Active - Recruiting

  • Hospital A Michallon, CHU Grenoble

    La Tronche,
    France

    Site Not Available

  • Charite Universitatsmedizin Berlin

    Berlin,
    Germany

    Site Not Available

  • Semmelweis University, 3rd Department of Internal Medicine

    Budapest,
    Hungary

    Site Not Available

  • Ospedale Luigi Sacco

    Milan,
    Italy

    Site Not Available

  • PHI University Clinic of Dermatology

    Skopje,
    Macedonia, The Former Yugoslav Republic of

    Site Not Available

  • For information on sites in Europe, please contact Pharming Technologies

    Leiden, 2333 CR
    Netherlands

    Site Not Available

  • PHI University Clinic of Dermatology

    Skopje,
    North Macedonia

    Active - Recruiting

  • Alesund Hospital

    Alesund,
    Norway

    Site Not Available

  • Stavanger University Hospital

    Stavanger,
    Norway

    Site Not Available

  • University Hospital Krakow

    Krakow,
    Poland

    Site Not Available

  • Bratislava University Hospital

    Bratislava,
    Slovakia

    Site Not Available

  • University Hospital Martin

    Martin,
    Slovakia

    Site Not Available

  • University Clinic Golnik

    Golnik,
    Slovenia

    Site Not Available

  • Ryhof County Hospital

    Jonkoping,
    Sweden

    Site Not Available

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