Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

Last updated: November 12, 2024
Sponsor: Seung-Jung Park
Overall Status: Active - Recruiting

Phase

N/A

Condition

Coronary Artery Disease

Chest Pain

Thrombosis

Treatment

N/A

Clinical Study ID

NCT01366404
CVRF2010-09
  • Ages > 35
  • All Genders

Study Summary

About 20,000 patients with FFR (Fractional Flow Reserve) will be enrolled and evaluated for the natural history of coronary lesions at 2 years clinical and imaging follow-up.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 35 years and older

  • FFR measurement on one and more coronary artery stenosis

  • Willing and able to provide informed, written consent

Exclusion

Exclusion Criteria:

  • Stenosis with TIMI<3 flow

  • Graft vessel

  • Ejection fraction < 30%

  • Angiographic evidence of extreme tortuosity or calcified coronary vessels

  • Suspected coronary spasm even after sufficient nitrate injected

  • Life expectancy <2 year

  • Planned cardiac surgery or planned major non cardiac surgery

  • Woman who are breastfeeding, pregnant or planning to become pregnant during thecourse of the study

Imaging study specific exclusion criteria

  • visually-estimated angiographic reference segment diameter of <2.75mm or >4.0mm

  • Inappropriate for IVUS/VH/OCT procedures : inability for imaging wire or catheter topass through the tight stenosis, severe calcification, angulation

Study Design

Total Participants: 20000
Study Start date:
June 01, 2011
Estimated Completion Date:
April 30, 2037

Study Description

This is a multicenter, prospective cohort. About 20,000 patients with FFR will be enrolled at multi centres in Korea.

Connect with a study center

  • Hallym University Sacred Heart Hospital

    Anyang,
    Korea, Republic of

    Active - Recruiting

  • Soon Chun Hyang University Hospital Bucheon

    Bucheon,
    Korea, Republic of

    Active - Recruiting

  • Chungbuk National University Hospital

    Cheongju,
    Korea, Republic of

    Active - Recruiting

  • Gangwon National Univ. Hospital

    Chuncheon,
    Korea, Republic of

    Active - Recruiting

  • Daegu Catholic University Center

    Daegu,
    Korea, Republic of

    Active - Recruiting

  • Keimyung University Dongsan Medical Center

    Daegu,
    Korea, Republic of

    Active - Recruiting

  • Kyungpook National university hospital

    Daegu,
    Korea, Republic of

    Active - Recruiting

  • Yeungnam University Medical Center

    Daegu,
    Korea, Republic of

    Active - Recruiting

  • Chungnam National University Hospital

    Daejeon,
    Korea, Republic of

    Active - Recruiting

  • The Catholic University of Korea, Deajeon St.Mary's hospital

    Daejeon,
    Korea, Republic of

    Active - Recruiting

  • Chungnam National University Hospital

    Deajeon,
    Korea, Republic of

    Site Not Available

  • Gangneung Asan Hospital

    Gangneung,
    Korea, Republic of

    Active - Recruiting

  • Chonnam National University Hospital

    Gwangju,
    Korea, Republic of

    Active - Recruiting

  • Inje University Ilsan Paik Hospital

    Ilsan,
    Korea, Republic of

    Active - Recruiting

  • Dong-A Medical Center

    Pusan,
    Korea, Republic of

    Active - Recruiting

  • Pusan National University Hospital

    Pusan,
    Korea, Republic of

    Active - Recruiting

  • Seoul university Bundang hospital

    Seongnam,
    Korea, Republic of

    Active - Recruiting

  • Asan Medical Center

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Gangnam Severance Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Hallym University Kangdong Sacred Heart Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Korea University Anam Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Korea University Guro Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Kyung-Hee University Hospital at Kangdong

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Seoul National University Boramae Medical Center

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Seoul National University Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • The Catholic University of Korea, Seoul St.Mary's Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • The Catholic University of Korea, Yeouido St. Mary's Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

  • Seoul university Bundang hospital

    Sungnam,
    Korea, Republic of

    Site Not Available

  • Ulsan University Hospital

    Ulsan,
    Korea, Republic of

    Active - Recruiting

  • Wonju Severance Christian Hospital

    Wonju,
    Korea, Republic of

    Active - Recruiting

  • Pusan National University Yangsan Hospital

    Yangsan,
    Korea, Republic of

    Active - Recruiting

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