A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or Placebo

Last updated: February 20, 2013
Sponsor: Pfizer
Overall Status: Completed

Phase

2

Condition

Rheumatoid Arthritis

Arthritis And Arthritic Pain

Joint Injuries

Treatment

N/A

Clinical Study ID

NCT01359150
A3921129
  • Ages > 18
  • All Genders

Study Summary

A Randomized, Double Blind, Placebo Controlled Phase 2 Study To assess the Immune Response Following Administration of Influenza and Pneumococcal Vaccines to Subjects with Rheumatoid Arthritis receiving CP-690,550 with and Without background Methotrexate

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • The subject must meet the American College of Rheumatology (ACR) classificationcriteria for the diagnosis of RA by satisfying at least four of the seven criteria.

  • The subject must have active disease at both screening and baseline

Exclusion

Exclusion Criteria:

  • History of any documented influenza or pneumococcal infection within the last 3months.

  • Receipt of any vaccine within 1 month prior to the initial study drug administration (CP-690,550 or placebo CP-690,550).

  • If a subject has received an influenza vaccine within 6 months or a pneumococcalvaccine within 5 years of initial study drug administration.

Study Design

Total Participants: 223
Study Start date:
September 01, 2011
Estimated Completion Date:
February 29, 2012

Connect with a study center

  • Pfizer Investigational Site

    Cieszyn, 43-400
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Koscian, 64-000
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Poznan, 60-773
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Torun, 87-100
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Warszawa, 02-256
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Wroclaw, 50-088
    Poland

    Site Not Available

  • Pfizer Investigational Site

    Gilbert, Arizona 85234
    United States

    Site Not Available

  • Pfizer Investigational Site

    Paradise Valley, Arizona 85253
    United States

    Site Not Available

  • Pfizer Investigational Site

    Hot Springs, Arkansas 71913
    United States

    Site Not Available

  • Pfizer Investigational Site

    Jonesboro, Arkansas 72401
    United States

    Site Not Available

  • Pfizer Investigational Site

    Fair Oaks, California 95628
    United States

    Site Not Available

  • Pfizer Investigational Site

    Los Angeles, California 90095
    United States

    Site Not Available

  • Pfizer Investigational Site

    Roseville, California 95661
    United States

    Site Not Available

  • Pfizer Investigational Site

    Upland, California 91786
    United States

    Site Not Available

  • Pfizer Investigational Site

    Boulder, Colorado 80304
    United States

    Site Not Available

  • Pfizer Investigational Site

    Trumbull, Connecticut 06611
    United States

    Site Not Available

  • Pfizer Investigational Site

    Daytona Beach, Florida 32174
    United States

    Site Not Available

  • Pfizer Investigational Site

    Jacksonville, Florida 32216
    United States

    Site Not Available

  • Pfizer Investigational Site

    Naples, Florida 34102
    United States

    Site Not Available

  • Pfizer Investigational Site

    New Port Richey, Florida 34652
    United States

    Site Not Available

  • Pfizer Investigational Site

    Ormond Beach, Florida 32174
    United States

    Site Not Available

  • Pfizer Investigational Site

    Port Richey, Florida 34668
    United States

    Site Not Available

  • Pfizer Investigational Site

    South Miami, Florida 33143
    United States

    Site Not Available

  • Pfizer Investigational Site

    Tampa, Florida 33613
    United States

    Site Not Available

  • Pfizer Investigational Site

    Venice, Florida 34292
    United States

    Site Not Available

  • Pfizer Investigational Site

    Zephyrhills, Florida 33542
    United States

    Site Not Available

  • Pfizer Investigational Site

    Burr Ridge, Illinois 60527
    United States

    Site Not Available

  • Pfizer Investigational Site

    Maywood, Illinois 60153
    United States

    Site Not Available

  • Pfizer Investigational Site

    Morton Grove, Illinois 60053
    United States

    Site Not Available

  • Pfizer Investigational Site

    Oakbrook Terrace, Illinois 60181
    United States

    Site Not Available

  • Pfizer Investigational Site

    Rockford, Illinois 61107
    United States

    Site Not Available

  • Pfizer Investigational Site

    Vernon Hills, Illinois 60061
    United States

    Site Not Available

  • Pfizer Investigational Site

    Wichita, Kansas 67208
    United States

    Site Not Available

  • Pfizer Investigational Site

    Lexington, Kentucky 40504
    United States

    Site Not Available

  • Pfizer Investigational Site

    Baton Rouge, Louisiana 70809
    United States

    Site Not Available

  • Pfizer Investigational Site

    Cumberland, Maryland 21502
    United States

    Site Not Available

  • Pfizer Investigational Site

    Leominster, Massachusetts 01453
    United States

    Site Not Available

  • Pfizer Investigational Site

    Worcester, Massachusetts 01608
    United States

    Site Not Available

  • Pfizer Investigational Site

    Bingham Farms, Michigan 48025
    United States

    Site Not Available

  • Pfizer Investigational Site

    Edina, Minnesota 55435
    United States

    Site Not Available

  • Pfizer Investigational Site

    Tupelo, Mississippi 38801
    United States

    Site Not Available

  • Pfizer Investigational Site

    Columbia, Missouri 65212
    United States

    Site Not Available

  • Pfizer Investigational Site

    Lebanon, New Hampshire 03756
    United States

    Site Not Available

  • Pfizer Investigational Site

    Albany, New York 12206
    United States

    Site Not Available

  • Pfizer Investigational Site

    Binghamton, New York 13905
    United States

    Site Not Available

  • Pfizer Investigational Site

    Olean, New York 14760
    United States

    Site Not Available

  • Pfizer Investigational Site

    Rochester, New York 14618
    United States

    Site Not Available

  • Pfizer Investigational Site

    Charlotte, North Carolina 28210
    United States

    Site Not Available

  • Pfizer Investigational Site

    Rocky Mount, North Carolina 27804
    United States

    Site Not Available

  • Pfizer Investigational Site

    Minot, North Dakota 58701
    United States

    Site Not Available

  • Pfizer Investigational Site

    Dayton, Ohio 45417
    United States

    Site Not Available

  • Pfizer Investigational Site

    Oklahoma City, Oklahoma 73112
    United States

    Site Not Available

  • Pfizer Investigational Site

    Bethlehem, Pennsylvania 18015
    United States

    Site Not Available

  • Pfizer Investigational Site

    Duncansville, Pennsylvania 16635
    United States

    Site Not Available

  • Pfizer Investigational Site

    Wyomissing, Pennsylvania 19610
    United States

    Site Not Available

  • Pfizer Investigational Site

    Greenville, South Carolina 29601
    United States

    Site Not Available

  • Pfizer Investigational Site

    Knoxville, Tennessee 37909
    United States

    Site Not Available

  • Pfizer Investigational Site

    Austin, Texas 78705
    United States

    Site Not Available

  • Pfizer Investigational Site

    Dallas, Texas 75231
    United States

    Site Not Available

  • Pfizer Investigational Site

    Mesquite, Texas 75150
    United States

    Site Not Available

  • Pfizer Investigational Site

    Seattle, Washington 98122
    United States

    Site Not Available

  • Pfizer Investigational Site

    Tacoma, Washington 98405
    United States

    Site Not Available

  • Pfizer Investigational Site

    Vancouver, Washington 98664
    United States

    Site Not Available

  • Pfizer Investigational Site

    Clarksburg, West Virginia 26301
    United States

    Site Not Available

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