Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke

Inclusion Criteria:

• single mono-hemispheric ischemic or hemorrhagic stroke

• 1st onset stroke patient

• Upper extremity functional deficit attributable to acute stroke

• A stage of at least 3 on brunnström pre-treatment

• Written signed consent

Exclusion Criteria:

• Multiple lesion

• Bilateral cortical lesion and motor problems

• Cerebellar, or brainstem lesions

• History of more than one stroke

• Uncontrolled medical problems, such as: cardiopulmonary disease, severe rheumatoidarthritis, active joint deformity of arthritic origin, active cancer, or renaldisease;

• Increased intracranial pressure

• History of seizure confirmed by interview and medical chart review

• Any individual who is on medication which is known to lower seizure threshold

• Other conditions that increase the risk of side effects due to rTMS procedures: ametal plate or metal object in the skull or eye, intracardiac line, increasedintracranial pressure, cardiac pacemaker, implanted medication pump, tricyclicantidepressants, neuroleptics, history of seizure in the immediate family

• An age of less than 20 years old

• Any current actively treated medical or surgical condition or neurological orpsychiatric illness other than stroke

• Complications that would prevent participation in the intervention, such as severepain and severe spasticity

• Inability to cooperate outcome measure-related task

• Severe language disturbances

• Serious cognitive deficits

• Non-vascular cause for the neurological symptoms other central nervous system

• Disorder or peripheral neuropathy of the upper extremity

• Taking medication which interrupt brain activity

• Women who are pregnant