The Effect Of Omega-3 Fatty Acids on Non-alcoholic Fatty Liver Disease

Last updated: January 22, 2014
Sponsor: University of Edinburgh
Overall Status: Completed

Phase

3

Condition

Liver Disease

Primary Biliary Cholangitis

Treatment

N/A

Clinical Study ID

NCT01277237
Edin2008-008275-34
2008-008275-34
  • Ages > 18
  • All Genders

Study Summary

There is preliminary evidence that Omega 3, a compound naturally found in fish oil, reduces the amount of fat stored in the liver and improves liver function. The purpose of this study is to see whether this observation is correct.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • a diagnosis of non-alcoholic fatty liver disease

  • fatty infiltration on ultrasound

  • abnormal serum liver function tests.

Exclusion

Exclusion Criteria:

  • any other identified cause of chronic liver disease

  • the prescription of medication which would cause non-alcoholic fatty liver - disease (e.g. tamoxifen)

  • already taking supplementary fish oil

  • alcohol intake of >20g/day for women, >40g/ day for men

  • known allergy to fish oil

  • on anticoagulants (antiplatelets are permitted)

  • severe heart failure (NYHA class IV)

  • pregnancy/ lactation

  • age under 18 years.

Study Design

Total Participants: 50
Study Start date:
September 01, 2010
Estimated Completion Date:
August 31, 2012

Connect with a study center

  • Royal Infirmary of Edinburgh

    Edinburgh, Lothian EH164SA
    United Kingdom

    Site Not Available

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