The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

Last updated: December 6, 2010
Sponsor: China Medical University Hospital
Overall Status: Trial Status Unknown

Phase

N/A

Condition

Thrombosis

Coronary Artery Disease

Myocardial Ischemia

Treatment

N/A

Clinical Study ID

NCT01255267
DMR99-IRB-041
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

In this study, we evaluate the acute coronary syndrome patients to see if there is correlation between platelet activity, genetic polymorphism (CYP2C19 and ABCB1), serum adipokines level, and Clopidogrel responsiveness.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age > 18 y/o

  2. Acute coronary syndrome patients

  3. Chronic coronary artery disease patients

  4. Healthy volunteers

Exclusion

Exclusion Criteria:

  1. Patient refusal

  2. Allergy to Clopidogrel

  3. Receive Gp IIb/IIIa inhibitor simultaneously

  4. Cancer history

  5. Severe renal and liver function impairment

  6. Coagulopathy

Study Design

Study Start date:
Estimated Completion Date:

Connect with a study center

  • China Medical University Hospital

    Taichung,
    Taiwan

    Active - Recruiting

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