Gargling With Green Tea for Prophylaxis of Influenza Infection in Teenagers

Last updated: February 12, 2013
Sponsor: University of Shizuoka
Overall Status: Trial Status Unknown

Phase

3

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT01225770
CT2010001
  • Ages 15-20
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Experimental and clinical studies in adults have reported that green tea catechins prevent influenza infection. In this clinical randomized study, the investigators aimed to determine the effects of gargling with green tea on the prophylaxis of influenza infection among high school teenagers.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • aged from 15 to 20 years

  • obtained written informed consent from both the student and parent beforeparticipation

  • possible to gargle during 90 days

  • possible to fill in questionnaire

Exclusion

Exclusion Criteria:

  • Possessing allergy to green tea

  • Possessing history of influenza infection within 6 months before entering the study

  • Possessing severe immune disease or whole body infection

  • severe cardiac, respiratory, renal, or hepatic dysfunction

  • diagnosed as inadequate to participate in the study by student doctor

Study Design

Total Participants: 640
Study Start date:
November 01, 2010
Estimated Completion Date:
August 31, 2014

Study Description

Influenza infection is the principal cause of acute respiratory illnesses and occurs in epidemic or pandemic worldwide. It spreads easily among high school students and from them to the rest of the community; therefore the prevention of influenza is very important.

Experimental studies have revealed that some components of green tea can prevent influenza infection in vitro. In clinically, gargling with green tea catechins has been reported to have possibilities to preventing influenza infection in adults; however, little clinical evidence in teenagers has so far been existed. Based on this background, the investigators designed a randomized study to evaluate the clinical efficacy of gargling with green tea in preventing influenza infection among high school students.

Connect with a study center

  • University of Shizuoka

    Shizuoka,
    Japan

    Active - Recruiting

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