Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities

Inclusion Criteria:

• Incompetence of SFJ
• Patients who are candidates for ETA [laser or radiofrequency ablation (RFA)]
• Symptomatic varicose veins
• Visible varicose veins
• Ability to comprehend and sign an informed consent and complete study questionnairesin English

Exclusion Criteria:

• Patients who only have telangiectatic or reticular veins (Clinical Finding C1, asassessed by CEAP Classification of Venous Disorders)
• Patients who have active ulceration on the leg to be treated (Clinical Finding C6, asassessed by CEAP Classification of Venous Disorders)
• Leg obesity impairing the ability to access the vein to be treated and/or to applypost-procedure compression bandaging and stockings
• Ultrasonographic or other evidence of current or previous deep vein thrombosis orocclusion
• Deep venous reflux unless clinically insignificant in comparison to superficial reflux
• Peripheral arterial disease precluding the wearing of post-procedure compressionbandaging and stockings
• Reduced mobility
• History of deep vein thrombosis, pulmonary embolism or stroke, including evidence ofprior DVT on duplex ultrasound
• Major surgery, prolonged hospitalization or pregnancy within 3 months of screening
• Major co-existing disease (e.g. malignancy; pulmonary disease; renal or hepaticinsufficiency; serious skin disease/condition that may compromise the ability of thepatient to comply with the compression protocol, etc.)
• Known allergic response to polidocanol or heparin, including history ofheparin-induced thrombocytopenia, and/or multiple allergic reactions
• Current alcohol or drug abuse
• Pregnant or lactating women
• Women of childbearing potential not using effective contraception