SwissNET - a Registry for Neuroendocrine Tumours in Switzerland

Last updated: January 20, 2020
Sponsor: University Hospital Inselspital, Berne
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neuroendocrine Carcinoma

Neoplasms

Abdominal Cancer

Treatment

N/A

Clinical Study ID

NCT01039922
BAG 035.0002-20/19
395/2014
  • All Genders

Study Summary

Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are regarded as a fairly rare disease. They are derived from the neuroendocrine system of the gastrointestinal tract and the pancreas and share common clinical features. So far, there is still uncertainty about the cell biology and mechanistic regulation of these tumours. Therefore targeted treatment is limited and management challenging. Treatment options include surgery, medical and ablative therapy, and more recently peptide-receptor radionuclide therapy. In order to better understand the characteristics of GEP-NETs and to evaluate treatment strategies, the SwissNET registry aims at the collection of data from patients presenting with a GEP-NET in Switzerland. Data will be entered prospectively and anonymized in a specifically designed database after the patient has given informed consent. All hospitals and general practitioners are invited to report on patients with a GEP-NET diagnosis and to participate to the registry. Data will be evaluated within regular time frames, focussing on types of GEP-NETs, treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate), thereby contributing to the better understanding of these tumours.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Neuroendocrine tumor irrespective of primary tumor location

  • Diagnosis in Switzerland

  • Given informed consent

Study Design

Total Participants: 1245
Study Start date:
January 01, 2008
Estimated Completion Date:
January 31, 2028

Study Description

Background

Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are generally classified as rare diseases. Little is known about their cell biology and their mechanistic regulation. During the last years, the incidence of GEP-NETs is continuously increasing worldwide. In parallel, novel treatment options are currently evaluated which may substantially improve prognosis of patients with NETs. Data on such tumours in Switzerland, however, is scarce and treatment strategies vary throughout the country.

Objective

To systematically and prospectively collect clinical information of patients with GEP-NETs in Switzerland based on a histologically confirmed diagnosis.

Methods

All NETs of both, gastrointestinal and pulmonary origin are included provided that patients have given informed consent. Data will be entered prospectively and anonymised in a specifically designed database. Contributing centres and general practitioners are visited by a study nurse, patient files are analysed and data is transferred to the database. In case of conflicting evidence, questions are resolved in collaboration with a review board of SwissNET. Evaluation of treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate) will take place within regular time frames.

Connect with a study center

  • Kantonsspital Aarau

    Aarau,
    Switzerland

    Active - Recruiting

  • Spitalnetz Bern Aarberg

    Aarberg,
    Switzerland

    Active - Recruiting

  • Bezirksspital Affoltern

    Affoltern am Albis,
    Switzerland

    Active - Recruiting

  • Kantonsspital Uri, Altdorf

    Altdorf,
    Switzerland

    Active - Recruiting

  • St. Claraspital

    Basel,
    Switzerland

    Active - Recruiting

  • Universitätsspital Basel

    Basel,
    Switzerland

    Active - Recruiting

  • Istituto oncologico della Svizzera italiana

    Bellinzona,
    Switzerland

    Active - Recruiting

  • Div. of Endocrinology, Diabetes and Clinical Nutrition, Bern University Hospital

    Bern, 3010
    Switzerland

    Active - Recruiting

  • Spital Tiefenau, Spitalnetz Bern

    Bern,
    Switzerland

    Active - Recruiting

  • Zieglerspital Bern

    Bern,
    Switzerland

    Active - Recruiting

  • Spitalzentrum Biel - Bienne

    Biel,
    Switzerland

    Active - Recruiting

  • Kantonsspital Bruderholz

    Bruderholz,
    Switzerland

    Active - Recruiting

  • Regionsspital Emmental

    Burgdorf,
    Switzerland

    Active - Recruiting

  • Kantonsspital Chur

    Chur,
    Switzerland

    Active - Recruiting

  • Private practise Dr. Mannhart

    Churwalden,
    Switzerland

    Active - Recruiting

  • Hôpital du Jura

    Delémont,
    Switzerland

    Active - Recruiting

  • Spital Dornach

    Dornach,
    Switzerland

    Active - Recruiting

  • Regionalspital Einsiedeln

    Einsiedeln,
    Switzerland

    Active - Recruiting

  • Hôpitaux Universitaires de Genève

    Geneva,
    Switzerland

    Active - Recruiting

  • Spital Grabs

    Grabs,
    Switzerland

    Active - Recruiting

  • See-Spital Horgen

    Horgen,
    Switzerland

    Active - Recruiting

  • Spital Zimmerberg

    Horgen,
    Switzerland

    Active - Recruiting

  • Fmi Spital Interlaken

    Interlaken,
    Switzerland

    Active - Recruiting

  • Spital Lachen

    Lachen,
    Switzerland

    Active - Recruiting

  • Spital Region Oberaargau

    Langenthal,
    Switzerland

    Active - Recruiting

  • Kantonsspital Laufen

    Laufen,
    Switzerland

    Active - Recruiting

  • Centre hospitalier universitaire vaudois, CHUV

    Lausanne,
    Switzerland

    Active - Recruiting

  • Kantonsspital Liestal

    Liestal,
    Switzerland

    Active - Recruiting

  • Hirslandenklinik St. Anna

    Luzern,
    Switzerland

    Active - Recruiting

  • Kantonsspital Luzern

    Luzern,
    Switzerland

    Active - Recruiting

  • Kantonsspital Sursee, Luzern

    Luzern,
    Switzerland

    Active - Recruiting

  • Kreisspital Männedorf

    Männedorf,
    Switzerland

    Active - Recruiting

  • Kantonsspital Münsterlingen

    Münsterlingen,
    Switzerland

    Active - Recruiting

  • Kantonsspital Olten

    Olten,
    Switzerland

    Active - Recruiting

  • Gesundheitszentrum Fricktal

    Rheinfelden,
    Switzerland

    Active - Recruiting

  • Kantonsspital Obwalden

    Sarnen,
    Switzerland

    Active - Recruiting

  • Spital Limmattal

    Schlieren,
    Switzerland

    Active - Recruiting

  • Spital Schwyz

    Schwyz,
    Switzerland

    Active - Recruiting

  • Privatpraxis Dr. H.J. Poths

    Seuzach,
    Switzerland

    Active - Recruiting

  • Centre hospitalier du centre du Valais

    Sion,
    Switzerland

    Active - Recruiting

  • Bürgerspital Solothurn

    Solothurn,
    Switzerland

    Active - Recruiting

  • Kantonsspital St. Gallen

    St. Gallen,
    Switzerland

    Active - Recruiting

  • Kantonsspital Nidwalden

    Stans,
    Switzerland

    Active - Recruiting

  • Thun Spital STS AG

    Thun,
    Switzerland

    Active - Recruiting

  • Spital Uster

    Uster,
    Switzerland

    Active - Recruiting

  • Regionalspital Visp

    Visp,
    Switzerland

    Active - Recruiting

  • Kantonsspital Winterthur

    Winterthur,
    Switzerland

    Active - Recruiting

  • Kantonsspital Wolhusen

    Wolhusen,
    Switzerland

    Active - Recruiting

  • Spital Zollikerberg

    Zollikerberg,
    Switzerland

    Active - Recruiting

  • Zuger Kantonsspital AG

    Zug,
    Switzerland

    Active - Recruiting

  • STS AG Spital Zweisimmen

    Zweisimmen,
    Switzerland

    Active - Recruiting

  • Pathologie Medica Zürich

    Zürich,
    Switzerland

    Active - Recruiting

  • Stadtspital Triemli

    Zürich,
    Switzerland

    Active - Recruiting

  • Stadtspital Waid

    Zürich,
    Switzerland

    Active - Recruiting

  • Universitätsspital Zürich

    Zürich,
    Switzerland

    Active - Recruiting

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