Effectiveness Study of Single Photon Emission Computed Tomography (SPECT) Versus Positron Emission Tomography (PET) Myocardial Perfusion Imaging

Last updated: October 30, 2014
Sponsor: Aspire Foundation
Overall Status: Completed

Phase

4

Condition

Vascular Diseases

Myocardial Ischemia

Chest Pain

Treatment

N/A

Clinical Study ID

NCT00976053
09-307
  • Ages 30-90
  • All Genders

Study Summary

The purpose of this study is to compare pharmacologic stress myocardial perfusion PET with pharmacologic stress myocardial perfusion SPECT in a near-simultaneous, head-to-head comparison in the same patient. The investigators hypothesize that pharmacologic stress myocardial perfusion PET will prove superior to pharmacologic stress myocardial perfusion SPECT as a first-line diagnostic test for higher-risk patients with known coronary artery disease (CAD) who present with symptoms consistent with possible worsening of their CAD.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • History of coronary artery disease

  • New or worsening symptoms

  • Out-patients and in-hospital patients

Exclusion

Exclusion Criteria:

  • Creatinine above 2.5 mg%

  • PCI within prior 6 months

  • Pregnant females

  • Cardiomyopathy (LVEF below 40%)

  • Significant valvular heart disease

  • Body mass index greater than 38

Study Design

Total Participants: 330
Study Start date:
June 01, 2009
Estimated Completion Date:
October 31, 2014

Connect with a study center

  • Saint Luke's Cardiovascular Consultants

    Kansas City, Missouri 64111
    United States

    Site Not Available

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