Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery

Inclusion Criteria:

• Children of both genders older than 13 months and younger than 30 months of age.

• Available for follow-up for at least 45 days at public day care centers funded by SãoPaulo City local government.

• Written informed consent signed by parents or legal guardians after reading andexplanation

Exclusion Criteria:

• Suspect/verified diagnosis of congenital or acquired immunodeficiency syndrome (AIDS)

• Suspect/verified diagnosis of malign neoplasia

• Children on treatment with high-dose systemic corticosteroids (equivalent toprednisone 2 mg/kg/day, for two or more weeks), or immunosuppressive therapy.

• Received a vaccine with live attenuated strain of virus within less than 30 days

• Suspect/verified diagnosis of chickenpox or has already been immunized againstchickenpox (varicella).

• Suspect/verified diagnosis of hypersensibility to any ingredient of the vaccine.

• One of the parents or legal guardians of the minor does not agree with the study.

• Any other circumstances that may potentially damage the minor or prevent proceduresfrom being carried out according to evaluation of the research team.

• Child shows signs or symptoms of an active intercurrent disease (e.g. fever, rash,etc.) that may interfere with the evaluation of adverse events after immunization atthe research team's discretion. In this case, the participant may be reevaluatedwithin the following three months in order to verify eligibility.