Augmentation of Screening Colonoscopy With Fecal Immunochemical Testing

Inclusion Criteria: Group I (positive colonoscopy)

• 18 to 75 years of age

• male or female

• willing to provide written informed consent

• In the event that the colonoscopy is incomplete, or polypectomy is partial, the abovepatients are eligible if a successful examination is completed within 6 months of theinadequate exam. Group II (negative colonoscopy)

• 50 to 69 years of age

• Male or female

• Willing to provide written informed consent

• In the event that the colonoscopy is incomplete, the patient is eligible if asuccessful examination is completed within 6 months of the inadequate exam.

Exclusion Criteria: Group I (positive colonoscopy)

• chronic use of coumadin

• history of previous GI malignancy, inflammatory bowel disease (Crohns disease,ulcerative colitis)

• age or health status contraindicates repeat colonoscopy

• history of Familial Polyposis or Hereditary Nonpolyposis Colon Cancer Syndrome

• The index colonoscopy resulted in a perforation requiring surgical repair

• An otherwise qualifying colonoscopy is followed by a recommendation for repeatcolonoscopy in ≤ 1 yr. Group II (negative colonoscopy)

• chronic use of coumadin

• history of previous GI malignancy, inflammatory bowel disease (Crohns disease,ulcerative colitis)

• age or health status contraindicates repeat colonoscopy

• history of Familial Polyposis or Hereditary Nonpolyposis Colon Cancer Syndrome

• The index colonoscopy resulted in a perforation requiring surgical repair

• Significant family history resulting in a recommendation for repeat colonoscopy in 5years or less