Comparison of Nadifloxacin Cream Alone and With Benzoyl Peroxide Solution in the Treatment of Acne

Last updated: March 24, 2009
Sponsor: Marmara University
Overall Status: Trial Status Unknown

Phase

3

Condition

Rash

Acne

Inflammatory Comedones

Treatment

N/A

Clinical Study ID

NCT00869492
mar-der1
dermatology1
  • Ages 14-40
  • All Genders

Study Summary

The purpose of this study is to determine whether using of nadifloxacine 1% cream and benzoyl peroxide 5% solution together is more effective than using nadifloxacine alone in the treatment of mild to moderate facial acne.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Clinical diagnosis of mild to moderate facial acne vulgaris

  • Must have at least 10 inflammatory and/or non-inflammatory and no more than 3nodulocystic acne lesions

Exclusion

Exclusion Criteria:

  • Nodulocystic acne lesions more than 3 and pure comedonal acne

  • Additional truncal acne needs systemic therapy

  • Usage of topical treatments for acne in last 2 weeks, systemic antibiotic in last 4weeks, systemic isotretinoin in last 6 months

  • Application of chemical peels and laser in last 4 weeks

  • Usage of hormones in last 3 months

  • Clinical signs of hyperandrogenism in females

  • Pregrancy and lactation

  • Hypersensitivity to interventions

  • Additional facial skin diseases (eg. atopic and seborreic dermatitis)

  • Photosensitive disorders and usage of drugs which can trigger Photosensitiveconditions

Study Design

Total Participants: 90
Study Start date:
August 01, 2008
Estimated Completion Date:
June 30, 2009

Study Description

Nadifloxacin; a new topical antibiotic for the treatment of acne has recently been marketed in our country. Only a few studies on its use and effectiviness could be found in the literature. Nadifloxacin may be an alternative to other topical antibiotics and benzoyl peroxide or its use along with benzoyl peroxide may be more effective and rational to prevent possible future resistance.

Connect with a study center

  • Marmara University school of medicine

    Istanbul,
    Turkey

    Site Not Available

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