Dexamethasone for Postoperative Nausea and Vomiting

Last updated: May 12, 2016
Sponsor: University of Jordan
Overall Status: Completed

Phase

4

Condition

Vomiting

Colic

Lactose Intolerance

Treatment

N/A

Clinical Study ID

NCT00825071
UJordan
  • Ages 18-70
  • All Genders

Study Summary

The investigators want to test the efficacy of these anesthetic antiemetic measures collectively with or without ondansetron or dexamethasone, in the prevention of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • (ASA) grade I and II, aged (18-70 years) who are scheduled for elective laparoscopiccholecystectomy under general anesthesia at the department of Anesthesia and IntensiveCare, University of Jordan, Amman, Jordan between November 2007 and March 2008

Exclusion

Exclusion Criteria:

  • All patients who received antiemetics or cortisone within 48 hr before surgery orthose who required opioids before and after surgeries

  • Pregnant, breast feeding ladies

  • Any patient with BMI (Body Mass Index) > 34 kg/m²

  • Patient with gastrointestinal, hepatic, renal, mental or psychiatric illnesses orthose with history of motion sickness were also excluded from the study protocol

Study Design

Total Participants: 180
Study Start date:
November 01, 2007
Estimated Completion Date:
March 31, 2008

Study Description

More than half of the patients undergoing laparoscopic cholecystectomy will have postoperative nausea and vomiting (PONV). PONV is related to surgical, anesthetic and patient factors.

We want to test the efficacy of these anesthetic antiemetic measures collectively with or without ondansetron or dexamethasone, in the prevention of PONV in patients undergoing laparoscopic cholecystectomy.

Three groups to be studied : (Group O) will receive 4 mg ondansetron, (Group D) will receive 8 mg dexamethasone and (Group P) will receive normal saline .

Connect with a study center

  • Jordan University Hospital

    Amman, 11942
    Jordan

    Site Not Available

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