YAZ Premenstrual Dysphoric Disorder (PMDD) in China

Inclusion Criteria:

• Chinese women of reproductive age 18-45 years (inclusive) with a diagnosis ofPremenstrual Dysphoric Disorder (PMDD)

Exclusion Criteria:

• Any formal psychotherapeutic counselling within 1 month before the screening visit (Visit 1) or used medication for Premenstrual Syndrome (PMS) or Premenstrual DysphoricDisorder (PMDD) including, but not limited to hormones, bromocriptine, GnRH agonists,vitamin B6 (>100 mg), calcium supplements (> 1500 mg/day), anxiolytics andantidepressants during the 3 month period prior to Visit 1

• Use of sleeping medication (including melatonin) for more than 3 days per month.

• Pregnancy or less than 3 menstrual cycles since delivery, abortion or lactation beforestart of treatment

• Obesity (body mass index or BMI > 30 kg/m2)

• Hypersensitivity to any ingredient of the study drug