Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From Cerebral Hemorrhage

Last updated: May 26, 2010
Sponsor: Fudan University
Overall Status: Trial Status Unknown

Phase

2/3

Condition

Brain Injury

Hemorrhage

Pneumonia

Treatment

N/A

Clinical Study ID

NCT00815737
rhubarb cerebral hemorrhage
  • Ages > 18
  • All Genders

Study Summary

This study will determine if rhubarb will reduced the incidence of pneumonia and improved recovery from an acute cerebral hemorrhage. The study is designed to look at both infection rate and overall recovery and recovery of motor function, for example muscle strength and coordination.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Occurrence of an acute cerebral hemorrhage (between 9 and 72 h after onset) with ascore of at least 6 on the National Institute of Health Stroke Scale (NIHSS), andpatient age of at least 18 years.

  • Have no pneumonia according to modified criteria of the U.S. Centers for DiseaseControl and Prevention (CDC)

  • Consistent with the Constipation of Phlegm-Heat Accumulation type by TraditionalChinese Medicine (TCM) standard

  • Patients or their representatives voluntarily take part in this study and signed theinformed consent

Exclusion

Exclusion Criteria:

  • Cerebral infarction, transient ischemic attack(TIA)

  • Subarachnoid hemorrhage

  • Proven cerebral embolism caused by tumor, Brain Trauma, cerebral parasitic disease,dysbolismus, fibrillation atrial resulted from rheumatic heart disease, coronary heartdisease, and other heart diseases

  • Clinical signs of infection on admission

  • Pregnant or breast-feeding

  • Allergic to rhubarb

  • Preceding or ongoing antibiotic therapy within the last 24 h

  • Participation in another interventional trial

  • Immunosuppressant treatment within the last 30 days

  • Combining severe clinical conditions such as liver, kidney, Hematopoietic System,endocrine system or psychological diseases

Study Design

Total Participants: 100
Study Start date:
January 01, 2009
Estimated Completion Date:

Connect with a study center

  • Zhongshan hospital of Fudan University

    Shanghai, Shanghai 200032
    China

    Site Not Available

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