A Study of Glaucoma or Ocular Hypertension in Patients Within the United States

Last updated: February 17, 2021
Sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Overall Status: Completed

Phase

3

Condition

Glaucoma

Ocular Hypertension

Vascular Diseases

Treatment

N/A

Clinical Study ID

NCT00800267
96TIPG005
A6641006
  • Ages > 18
  • All Genders

Study Summary

Safety and efficacy study comparing between fixed combination latanoprost-timolol and its component parts.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Unilateral or bilateral primary open angle glaucoma, capsular glaucoma, pigmentaryglaucoma or ocular hypertension.
  • Patients currently on IOP reducing therapy: IOP greater than or equal to 25mmHg (LtwoIOP determinations at pre-study separated by at least one hour) OR Patients withoutIOP reducing therapy: IOP greater than or equal to 30mmHg (two IOP determinations atpre-study separated by at least one hour).

Exclusion

Exclusion Criteria:

  • History of acute angle closure or closed/barely open anterior chamber angle.
  • Current use of contact lenses.
  • Ocular surgery or argon laser trabeculoplasty (ALT) within three months prior topre-study visit.
  • Ocular inflammation/infection occurring within three months prior to pre-study visit.
  • Hypersensitivity to benzalkonium chloride or to any other component of the study drugsolutions.
  • Other abnormal ocular condition or symptom preventing the patient from entering thestudy, according to the investigator's judgement.
  • Patients with conditions in which treatment with B-blocking agents arecontraindicated: cardiac failure, sinus bradycardia, second and third degreeatrio-ventricular block.
  • Patients with conditions in which treatment with B-blocking agents arecontraindicated: bronchial asthma, history of bronchial asthma or chronic obstructivepulmonary disease.
  • Inability to adhere to treatment/visit plan.
  • Have participated in any other clinical study within one month prior to pre-studyvisit.

Study Design

Total Participants: 418
Study Start date:
July 01, 1997
Estimated Completion Date:
June 30, 1999

Connect with a study center

  • Pfizer Investigational Site

    Anaheim, California 92807
    United States

    Site Not Available

  • Pfizer Investigational Site

    Sacramento, California 95819
    United States

    Site Not Available

  • Pfizer Investigational Site

    San Francisco, California 94115
    United States

    Site Not Available

  • Pfizer Investigational Site

    Boulder, Colorado 80304-3573
    United States

    Site Not Available

  • Pfizer Investigational Site

    Denver, Colorado 80210
    United States

    Site Not Available

  • Pfizer Investigational Site

    Largo, Florida 34640
    United States

    Site Not Available

  • Pfizer Investigational Site

    Tampa, Florida 33613
    United States

    Site Not Available

  • Pfizer Investigational Site

    Atlanta, Georgia 30322
    United States

    Site Not Available

  • Pfizer Investigational Site

    East Point, Georgia 30223
    United States

    Site Not Available

  • Pfizer Investigational Site

    Griffin, Georgia 30223
    United States

    Site Not Available

  • Pfizer Investigational Site

    Morrow, Georgia 30260
    United States

    Site Not Available

  • Pfizer Investigational Site

    Chicago, Illinois 60612
    United States

    Site Not Available

  • Pfizer Investigational Site

    Wheaton, Illinois 60187
    United States

    Site Not Available

  • Pfizer Investigational Site

    Elkhart, Indiana 46515
    United States

    Site Not Available

  • Pfizer Investigational Site

    Mishawaka, Indiana 46545
    United States

    Site Not Available

  • Pfizer Investigational Site

    South Bend, Indiana 46601
    United States

    Site Not Available

  • Pfizer Investigational Site

    Iowa City, Iowa 52245
    United States

    Site Not Available

  • Pfizer Investigational Site

    Louisville, Kentucky 40207
    United States

    Site Not Available

  • Pfizer Investigational Site

    Baltimore, Maryland 21201
    United States

    Site Not Available

  • Pfizer Investigational Site

    Owings Mills, Maryland 21117
    United States

    Site Not Available

  • Pfizer Investigational Site

    Boston, Massachusetts 02111
    United States

    Site Not Available

  • Pfizer Investigational Site

    Golden Valley, Minnesota 55422
    United States

    Site Not Available

  • Pfizer Investigational Site

    Minneapolis, Minnesota 55421
    United States

    Site Not Available

  • Pfizer Investigational Site

    Kansas City, Missouri 64114
    United States

    Site Not Available

  • Pfizer Investigational Site

    Warrenburg, Missouri 64093
    United States

    Site Not Available

  • Pfizer Investigational Site

    Warrensburg, Missouri 64093
    United States

    Site Not Available

  • Pfizer Investigational Site

    Concord, New Hampshire 03301
    United States

    Site Not Available

  • Pfizer Investigational Site

    South Plainfield, New Jersey 07080
    United States

    Site Not Available

  • Pfizer Investigational Site

    Charlotte, North Carolina 28210
    United States

    Site Not Available

  • Pfizer Investigational Site

    Matthews, North Carolina 28105
    United States

    Site Not Available

  • Pfizer Investigational Site

    Monroe, North Carolina 28112
    United States

    Site Not Available

  • Pfizer Investigational Site

    Portland, Oregon 97201
    United States

    Site Not Available

  • Pfizer Investigational Site

    Wyomissing, Pennsylvania 19610
    United States

    Site Not Available

  • Pfizer Investigational Site

    Charleston, South Carolina 29412
    United States

    Site Not Available

  • Pfizer Investigational Site

    Mount Pleasant, South Carolina 29464-3245
    United States

    Site Not Available

  • Pfizer Investigational Site

    Memphis, Tennessee 38119
    United States

    Site Not Available

  • Pfizer Investigational Site

    Austin, Texas 78731-4941
    United States

    Site Not Available

  • Pfizer Investigational Site

    Galveston, Texas 77555-1141
    United States

    Site Not Available

  • Pfizer Investigational Site

    Houston, Texas 77030
    United States

    Site Not Available

  • Pfizer Investigational Site

    Charlottesville, Virginia
    United States

    Site Not Available

  • Pfizer Investigational Site

    Richmond, Virginia 23219
    United States

    Site Not Available

  • Pfizer Investigational Site

    Tacoma, Washington 98431
    United States

    Site Not Available

  • Pfizer Investigational Site

    Madison, Wisconsin 53715
    United States

    Site Not Available

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