Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study

Inclusion Criteria:

1. the presence of 2 of the following 3 criteria:

2. a clinical history of central chest oppression, pain, or tightness lasting for ≥30 minutes

3. typical electrocardiographic changes (i.e., ST-segment elevation of >0.1 mV in ≥1limb or 2 precordial leads, ST-segment depression >0.1 mV in ≥2 leads, abnormal Qwaves, or T-wave inversion in ≥2 leads)

4. an increase in the serum creatine kinase levels to >2 times the normal laboratoryvalue.

5. the serum level of LDL-C is ≥70 and 130> mg/dl in the first blood examination soonafter admission

Exclusion Criteria:

1. concurrent therapy with any HMG-CoA reductase inhibitor

2. previous history of the side effects associated with any HMG-CoA reductase inhibitor

3. life-threatening arrhythmia

4. severe chronic congestive heart failure

5. hepatic dysfunction

6. renal failure

7. cerebrovascular disease

8. poor controlled diabetes

9. pregnancy, lactation

10. age <20 years

11. disability of taking medicine or absence of a written informed consent

12. Patients whom the doctors consider inappropriate by any other reason