A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic Bronchitis

Last updated: October 20, 2008
Sponsor: Pfizer
Overall Status: Completed

Phase

3

Condition

Bronchitis

Treatment

N/A

Clinical Study ID

NCT00649831
A0661045
  • Ages 36-74
  • All Genders

Study Summary

This study compared the clinical efficacy and safety of azithromycin with that of amoxicillin-clavulanic acid, in patients between the ages of 35 and 75 years, presenting with an exacerbation of chronic bronchitis.

Eligibility Criteria

Inclusion

Inclusion Criteria: Inclusion Criteria:

  • Outpatients presenting with an exacerbation of chronic bronchitis including: chronicbronchitis with obstructive respiratory disorders documented by a forced expiratoryvolume of below 80% and higher than 35% of the theoretical value, within the previous 12 months; and thought to be of infectious origin

Exclusion

Exclusion Criteria: Exclusion Criteria:

  • Patient not presenting with the associated signs of an exacerbation

  • Patient presenting with clinical signs suggestive of pneumonopathy at inclusion

  • Patient requiring hospitalisation in intensive care

Study Design

Total Participants: 250
Study Start date:
October 01, 2002
Estimated Completion Date:
June 30, 2003

Connect with a study center

  • Pfizer Investigational Site

    Anzin, 59410
    France

    Site Not Available

  • Pfizer Investigational Site

    Avignon, 84 000
    France

    Site Not Available

  • Pfizer Investigational Site

    Dijon, 21000
    France

    Site Not Available

  • Pfizer Investigational Site

    Equeurdreville Hainneville, 50120
    France

    Site Not Available

  • Pfizer Investigational Site

    Escaudain, 59 124
    France

    Site Not Available

  • Pfizer Investigational Site

    Le Grand Quevilly, 76120
    France

    Site Not Available

  • Pfizer Investigational Site

    Les Lilas, 93 260
    France

    Site Not Available

  • Pfizer Investigational Site

    Lyon, 69001
    France

    Site Not Available

  • Pfizer Investigational Site

    Mantes La Jolie, 78200
    France

    Site Not Available

  • Pfizer Investigational Site

    Maromme, 76150
    France

    Site Not Available

  • Pfizer Investigational Site

    Marseille, 13 008
    France

    Site Not Available

  • Pfizer Investigational Site

    Maubeuge, 59600
    France

    Site Not Available

  • Pfizer Investigational Site

    Mont Saint Martin, 54350
    France

    Site Not Available

  • Pfizer Investigational Site

    Nancy, 54000
    France

    Site Not Available

  • Pfizer Investigational Site

    Paris, 75012
    France

    Site Not Available

  • Pfizer Investigational Site

    Saint Aulaire, 19 130
    France

    Site Not Available

  • Pfizer Investigational Site

    Savigny, 91600
    France

    Site Not Available

  • Pfizer Investigational Site

    Soissons, 02 200
    France

    Site Not Available

  • Pfizer Investigational Site

    Tourcoing, 59200
    France

    Site Not Available

  • Pfizer Investigational Site

    Tulette, 26 790
    France

    Site Not Available

  • Pfizer Investigational Site

    Valenton, 94460
    France

    Site Not Available

  • Pfizer Investigational Site

    Vaux S/ Seine, 78740
    France

    Site Not Available

  • Pfizer Investigational Site

    Villejuif, 94800
    France

    Site Not Available

  • Pfizer Investigational Site

    Vincennes, 94300
    France

    Site Not Available

  • Pfizer Investigational Site

    Vitry, 94 400
    France

    Site Not Available

  • Pfizer Investigational Site

    Wattrelos, 59150
    France

    Site Not Available

  • Pfizer Investigational Site

    Yerres, 91330
    France

    Site Not Available

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