Estimating Volume Using LiDCO

Last updated: January 20, 2016
Sponsor: Duke University
Overall Status: Completed

Phase

N/A

Condition

Cerebral Ischemia

Blood Clots

Neurologic Disorders

Treatment

N/A

Clinical Study ID

NCT00571441
Pro00002786
  • Ages > 18
  • All Genders

Study Summary

We hypothesize that the stroke volume variation measured using the commercially available LiDCO monitor provides a reasonable estimate of volume when compared to standard measures. This study will collate data that is already being collected by the bedside nurses.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Admitted to the neurocritical care unit have an arterial line in place alreadyconnected to LiDCO monitor Physician order for monitoring intake and output

Exclusion

Exclusion Criteria:

  • pregnant females

Study Design

Total Participants: 34
Study Start date:
December 01, 2007
Estimated Completion Date:
December 31, 2008

Study Description

Objective: To compare measurement of stroke volume variance with intake/output measurements, weight, BUN/Creatnine values, and central venous pressure.

Design: Non-experimental, non-randomized observational comparative study.

Setting: The sixteen bed Neurocritical Care Unit at Duke University Hospital.

Patients: 45 adult (over 18 years) subjects with intracranial pathology who require volume resuscitation. Only patients with current LiDCO monitoring will be considered eligible for inclusion in the study.

Interventions: This is an observational study. Subjects will receive standard-of-care treatment without additional intervention.

Data Analysis: All data will be collected by the principal investigator / study coordinator. Personal patient information will be removed (deidentified) from the permanent data collection records to protect patient confidentiality. Data collected will be entered into a Microsoft Excel electronic spreadsheet and will be saved on a USB Disk drive to be stored in a locked cabinet in the investigator's office. Statistical analysis using SAS v9.1, (Cary, NC) will be conducted with a level of significance set at .05 (alpha) using standardized comparative analysis techniques.

Connect with a study center

  • Duke University

    Durham, North Carolina 27705
    United States

    Site Not Available

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