Study of Efficacy of Levofloxacin 0.5% Ophthalmic Solution Administered Three Times a Day for Bacterial Conjunctivitis

Inclusion Criteria:

• Male and female patients between 18 and 70 years of age

• Patients with Conjunctivitis (defined as the presence of three cardinal signs:conjunctival discharge, bulbar conjunctival injection and palpebral conjunctivalinjection)

• Patients who have given and signed informed consent

• The ability and willingness to comply with all study procedures

Exclusion Criteria:

• Insulin Dependent Diabetes Mellitus (IDDM)

• Patients with keratitis or hordeolum

• Glaucoma

• Sjogren's Syndrom and "Sick Eye's Syndrom".

• Ectropion, entropion;

• Using contact lenses during the study

• Poor visual acuity in the other eye

• Prior and concurrent concomitant treatment glycocorticosteroids, immunosupressivetherapy, if these treatments have not stopped at least 3 months prior to the start ofthe study;

• Concurrent use of non- steriodal anti- inflammatory drugs (NSAIDs), with the exceptionof low- dose aspirin. (see par. 11.5)

• Prior and concurrent systemic antibiotic treatment during last 7 days before thebeginning the study.(see par. 11.5)

• Concurrent other eye drops

• All ocular surgeries which were performed less than 6 months before the beginning ofthe study.

• Any clinical condition, which, in the opinion of the investigator would not allow safecompletion of the protocol.

• History of any malignancy within the past 5 years prior to study entry, except basalcell or squamous cell skin carcinoma.

• Hypersensitivity to fluoroquinolons and benzalkonium chloride;

• Intended or ascertained pregnancy or lactation;

• Participation in a clinical trial within last 30 days.