BOSCOT : A Randomised Controlled Trial of Cognitive Behavioural Therapy in Borderline Personality Disorder

Last updated: September 29, 2007
Sponsor: University of Aberdeen
Overall Status: Completed

Phase

3

Condition

Borderline Personality Disorder

Schizotypal Personality Disorder (Spd)

Mood Disorders

Treatment

N/A

Clinical Study ID

NCT00538135
064027/Z/01/Z
  • Ages 18-65
  • All Genders

Study Summary

The aim of the study was to investigate if the addition of cognitive behavioural therapy to treatment as usual (CBT plus TAU) in participants with borderline personality disorder would decrease the number of participants with emergency (i.e. unplanned) psychiatric or accident and emergency room contact or episode of deliberate self-harm over twelve months treatment and twelve months follow-up, compared with treatment as usual (TAU). The study also examined whether CBT plus TAU would lead to superior improvement in quality of life, social, cognitive and mental health functioning than TAU alone.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Aged between 18 and 65.

  2. Met criteria for at least 5 items of the borderline personality disorder using theStructured Clinical Interview for DSM IV Axis II Personality Disorders (SCID -II)(First, Gibbon, Spitzer, Williams & Benjamin, 1997)

  3. Had received either in-patient psychiatric services or an assessment at Accident andEmergency services or an episode of deliberate self-harm (either suicidal act orself-mutilation) in the previous 12 months.

  4. Able to give informed consent.

Exclusion

Exclusion Criteria:

  1. Currently receiving in-patient treatment for a mental state disorder,

  2. Currently receiving a systematic psychological therapy or specialist service,particularly psychodynamic psychotherapy,

  3. Insufficient knowledge of English to enable them to be assessed adequately and tounderstand the treatment approach,

  4. Temporarily resident in the area,

  5. The existence of an organic illness, mental impairment, alcohol or drug dependence,schizophrenia or bipolar affective disorder, as assessed by SCID I,/P (W/ PsychoticScreen)(version 2) (First, Spitzer, Gibbon, Williams, 1996).

Study Design

Total Participants: 106
Study Start date:
February 01, 2002
Estimated Completion Date:
March 31, 2005

Study Description

The trial is being carried out in three centres in the UK: Glasgow, London and Ayrshire (Ayrshire and Arran). Treatment as Usual (TAU) therefore reflected what is likely to be available in the UK.

Patients were eligible if they satisfied the following criteria:

  1. Aged between 18 and 65.

  2. Met criteria for at least 5 items of the borderline personality disorder using the Structured Clinical Interview for DSM IV Axis II Personality Disorders (SCID -II)(First, Gibbon, Spitzer, Williams & Benjamin, 1997)

  3. Had received either in-patient psychiatric services or an assessment at Accident and Emergency services or an episode of deliberate self-harm (either suicidal act or self-mutilation) in the previous 12 months.

  4. Able to give informed consent.

Exclusion criteria were as follows:

  1. Currently receiving in-patient treatment for a mental state disorder,

  2. Currently receiving a systematic psychological therapy or specialist service, particularly psychodynamic psychotherapy,

  3. Insufficient knowledge of English to enable them to be assessed adequately and to understand the treatment approach,

  4. Temporarily resident in the area,

  5. The existence of an organic illness, mental impairment, alcohol or drug dependence, schizophrenia or bipolar affective disorder, as assessed by SCID I,/P (W/ Psychotic Screen)(version 2) (First, Spitzer, Gibbon, Williams, 1996).

Connect with a study center

  • Psychological Medicine

    Glasgow, Strathclyde G12 0XH
    United Kingdom

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.