The Effect of Somatropin Treatment in Adult Patients on Chronic Dialysis

Inclusion Criteria:

• Serum albumin as specified in protocol

• Malnourished (based on serum albumin value below 40 g/L, assessed centrally)

• Stable (for 3 months or more) and adequate haemodialysis treatment three months priorto enrolment as defined by Kt/V of more than 1.2

Exclusion Criteria:

• Active malignant disease

• Critical illness requiring treatment in an intensive care unit (ICU)

• Uncontrolled treated/untreated hypertension

• Patients on chronic (more than 3 months) treatment with steroids in doses of more than 10 mg/day prednisolone (or equivalent)

• Patients treated with immunosuppressive agents

• Known Growth Hormone Deficiency

• Patients suffering from any clinically significant disease history in the opinion ofthe investigator

• Severe illness as defined in the protocol (as judged by the investigator)