Evaluation of Topical B12 for the Treatment of Childhood Atopic Dermatitis

Last updated: April 23, 2007
Sponsor: Spartanburg Regional Family Medicine
Overall Status: Trial Status Unknown

Phase

N/A

Condition

Atopic Dermatitis

Allergy

Rash

Treatment

N/A

Clinical Study ID

NCT00465699
IRB00001369
  • Ages 6-18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study is being done to see in B12 applied to the skin will improve the symptoms of eczema in children compared to a placebo creme

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • children presenting to the Center for Family Medicine or Regional Pediatrics betweenthe ages of 6 months and 18 years old with atopic dermatitis

Exclusion

Exclusion Criteria:

  • unwillingness of parent to consent to study protocol, pregnancy or lactation, eczemawith superinfection present, known history of allergy to Vitamin B12 or components ofthe base cream, topical treatment with corticosteroids in the 4 weeks prior toenrollment

Study Design

Total Participants: 50
Study Start date:
April 01, 2007
Estimated Completion Date:
April 30, 2007

Study Description

INTRODUCTION: Atopic dermatitis is a prevalent disease process in children, affecting up to 20% of children in the United States. Various treatment options are available to treat atopic dermatitis to include topical emollients, topical steroids, and topical calcineurin inhibitors. Each treatment option has benefits and potential risks. This study was done to determine if topical B12 could be a tolerable and efficacious alternative treatment option in this population.

METHODS: The study was conducted as a placebo-controlled, double-blind, prospective, randomized clinical trial with intraindividual left ⁄ right comparison. Parents were given 2 containers of creams and instructed to apply the Vitamin B12 cream to one side of the body and the placebo cream to the contralateral side according to the randomization scheme.

Connect with a study center

  • Center for Family Medicine

    Spartanburg, South Carolina 29303
    United States

    Active - Recruiting

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