Comparison of Bowel Preparation in Virtual Colonoscopy (VC) - Patient Experience

Last updated: July 23, 2010
Sponsor: London North West Healthcare NHS Trust
Overall Status: Trial Not Available

Phase

4

Condition

Rectal Cancer

Colon Cancer; Rectal Cancer

Colorectal Cancer

Treatment

N/A

Clinical Study ID

NCT00460837
07.senna.SMH
  • Ages > 18
  • All Genders

Study Summary

The study will compare patient's experience between those taking a standard bowel cleansing regimen with minimal laxative tagging regimen of senna and gastrofin. Additionally comparing any possible reduction in diagnostic accuracy that may ensue from an increased quantity of retained faecal residue.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • patients with symptoms attributable to colorectal cancer

Exclusion

Exclusion Criteria:

  • patients with known colorectal cancer referred for staging VC

  • patients who take laxatives regularly or with previous inadequate colonic examinationdue to excessive faecal residue

  • patients deemed too frail to undergo full bowel preparation

Study Design

Total Participants: 150
Study Start date:
November 01, 2007
Estimated Completion Date:
March 31, 2009

Study Description

Bowel cleansing with high dose laxative is the standard bowel preparation prior to whole colon investigations but such regimens are associated with considerable patient discomfort and inconvenience, potentially affecting compliance rates [1-3].

Unlike existing whole colon investigations (conventional colonoscopy and barium enema), reduced laxative regimens can be successfully used with VC, with the aim of improving patient experience, whilst maintaining diagnostic accuracy. These regimens utilize faecal tagging; a method of labeling residual faeces and fluid with radiodense liquids, such as iodine or barium based fluids, which are taken orally by the patient. Once faecal residue and fluid is labeled in this way, it can easily be discriminated from true pathology (which remains 'untagged').

We are proposing to compare different bowel preparation regimens, and ascertain patient experience of the different regimes, while monitoring diagnostic accuracy of the 2 different regiments.

Connect with a study center

  • St Mark's Hospital, North West London Hospitals NHS Trust

    London, Middlesex HA1 3UJ
    United Kingdom

    Site Not Available

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