Phase
Condition
Metabolic Syndrome
Metabolic Disorders
High Cholesterol (Hyperlipidemia)
Treatment
ezetimibe (+) simvastatin
Comparator: Placebo (unspecified)
Comparator: atorvastatin calcium
Clinical Study ID
Ages 18-79 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Patients 18 to 79 years of age with metabolic syndrome and hypercholesterolemia athigh risk for coronary heart disease (CHD) with LDL-C above 70 mg/dL or 100 mg/dLdepending on their CHD risk category
Exclusion
Exclusion Criteria:
A condition which, in the opinion of the investigator, pose a risk to the patient orinterfere with participating in the study
Patient is likely to be greater than 20% noncompliant in taking study medications
Patients with chronic medical conditions
Patients with unstable doses of medications
Pregnant or lactating women, women intending to become pregnant
Patient is currently receiving prescription therapy with statins or otherlipid-altering medications
Patient with Type 1 or Type 2 diabetes mellitus that is poorly controlled, newlydiagnosed, or is taking new or recently adjusted antidiabetic pharmacotherapy (withthe exception of +/- 10 units of insulin)