Chemotherapy With or Without Bevacizumab in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer That Can Be Removed By Surgery

Last updated: September 12, 2017
Sponsor: NSABP Foundation Inc
Overall Status: Trial Status Unknown

Phase

3

Condition

Breast Cancer

Cancer

Treatment

N/A

Clinical Study ID

NCT00408408
NSABP B-40
NSABP B-40
  • Ages 18-120
  • Female

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of breast cancer by blocking blood flow to the tumor. Giving chemotherapy and bevacizumab before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving bevacizumab after surgery may kill any tumor cells that remain after surgery. It is not yet known which chemotherapy regimen is more effective with or without bevacizumab in treating breast cancer.

PURPOSE: This randomized phase III trial is studying six different chemotherapy regimens to compare how well they work with or without bevacizumab in treating women with stage I, stage II, or stage IIIA breast cancer that can be removed by surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • The patient must have consented to participate and must have signed and dated anappropriate Institutional Review Board (IRB)-approved consent form that conforms tofederal and institutional guidelines for the study treatment and submission ofpre-entry core biopsy material for correlative studies.

  • Patients must be female.

  • Patients must be 18 years of age or older.

  • Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

  • The diagnosis of invasive adenocarcinoma of the breast must have been made by coreneedle biopsy.

  • The primary breast tumor must be palpable and measure greater than or equal to 2.0 cmon physical exam.

  • All patients must have their left ventricular ejection fraction (LVEF) assessed bymultigated acquisition (MUGA) scan or echocardiogram within 3 months prior to studyentry. The LVEF must be greater than or equal to the lower limit of normal (LLN) forthe cardiac imaging facility performing the study. Note: If the cardiac imagingfacility cannot provide a LLN, use 50% as the LLN value.

  • Note: Since the pre-entry LVEF serves as the baseline for comparing subsequent LVEFassessments to determine if bevacizumab therapy can be continued, it is critical thatthis baseline study be an accurate assessment of the patient's LVEF. If the baselineLVEF is greater than 75%, the investigator should have the study reviewed for accuracyprior to study entry. Following study entry, the LVEF determination may be reviewed upuntil the time of the post-chemotherapy (preoperative) evaluation. Please note that ifa more accurate value is obtained from the review of the baseline MUGA orechocardiogram, the correct value must be submitted to the NSABP before thepost-chemotherapy (preoperative) MUGA or echocardiogram is performed or it cannot beused for managing postoperative bevacizumab.

  • All patients must have an EKG within 3 months prior to study entry.

  • At the time of randomization:

  • Absolute neutrophil count (ANC) must be greater than or equal to 1200/mm3.

  • Platelet count must be greater than or equal to 100,000/mm3.

  • Hemoglobin must be greater than or equal to 10 g/dL.

  • There must be evidence of adequate hepatic function by these criteria:

  • Total bilirubin must be less than or equal to the ULN for the lab unless thepatient has a grade 1 bilirubin elevation (greater than ULN to 1.5 x ULN)resulting from Gilbert's disease or similar syndrome due to slow conjugation ofbilirubin; and

  • Alkaline phosphatase must be less than or equal 2.5 x ULN for the lab; and

  • Aspartate Aminotransferase (AST) must be less than or equal to 1.5 x ULN for thelab.

  • Alkaline phosphatase and AST may not both be greater than the ULN. For example,if the alkaline phosphatase is greater than the ULN but less than or equal 2.5 xULN, then the AST must be less than or equal the ULN. If the AST is greater thanthe ULN but less than or equal 1.5 x ULN, then the alkaline phosphatase must beless than or equal ULN.

  • Patients with either skeletal pain or alkaline phosphatase that is greater than ULNbut less than or equal 2.5 x ULN are eligible for inclusion in the study if bone scansdo not demonstrate metastatic disease. Suspicious findings on bone scan must beconfirmed as benign by x-ray, MRI, or biopsy.

  • Patients with AST or alkaline phosphatase greater than ULN are eligible for inclusionin the study if liver imaging does not demonstrate metastatic disease and adequatebone marrow and liver function results as described above are met.

  • The following criteria for evidence of adequate renal function must be met:

  • Serum creatinine less than or equal ULN for the lab.

  • Calculated creatinine clearance must be greater than 50 mL/min.

  • Urine protein/urine creatinine (UPC) ratio must be less than 1.0.

  • Patient must be able to swallow oral medications.

Exclusion

Exclusion criteria:

  • Tumor determined to be strongly human epidermal growth factor receptor 2 (HER2)-positive by immunohistochemistry (3+) or by fluorescent in situ hybridization (positive for gene amplification).

  • Excisional or incisional biopsy for this primary breast tumor.

  • Surgical axillary staging procedure prior to study entry. Exceptions: 1) Fine NeedleAspiration (FNA) or core biopsy of an axillary node is permitted for any patient, and

  1. although not recommended, a pre-neoadjuvant therapy sentinel lymph node biopsy forpatients with clinically negative axillary nodes is permitted.
  • Tumors clinically staged as T4.

  • Ipsilateral cN2b or cN3 disease. (Patients with cN1 or cN2a disease are eligible.)

  • Definitive clinical or radiologic evidence of metastatic disease.

  • Synchronous bilateral breast cancer (invasive or DCIS).

  • Treatment including radiation therapy, chemotherapy, biotherapy, and/or hormonaltherapy for the currently diagnosed breast cancer prior to study entry.

  • Any sex hormonal therapy, e.g., birth control pills, ovarian hormonal replacementtherapy, etc. (These patients are eligible if this therapy is discontinued prior torandomization.)

  • Therapy with any hormonal agent such as raloxifene, tamoxifen, or other selectiveestrogen receptor modulator (SERM), either for osteoporosis or breast cancerprevention. (Patients are eligible only if these medications are discontinued prior torandomization.)

  • Prior history of breast cancer, including DCIS. (Patients with a history of lobularcarcinoma in situ [LCIS] are eligible.)

  • Prior therapy with anthracyclines, taxanes, capecitabine, 5-FU (fluorouracil),gemcitabine, or bevacizumab for any malignancy.

  • Other malignancies unless the patient is considered to be disease-free for 5 or moreyears prior to randomization and is deemed by her physician to be at low risk forrecurrence. Patients with the following cancers are eligible if diagnosed and treatedwithin the past 5 years: carcinoma in situ of the cervix, carcinoma in situ of thecolon, melanoma in situ, and basal cell and squamous cell carcinoma of the skin.

  • Cardiac disease that would preclude the use of anthracyclines. This includes:

  • angina pectoris that requires the use of anti-anginal medication;

  • history of documented congestive heart failure;

  • serious cardiac arrhythmia requiring medication;

  • severe conduction abnormality;

  • valvular disease with documented cardiac function compromise; and

  • uncontrolled hypertension defined as BP greater than 150/90 on antihypertensivetherapy. (Patients with hypertension that is well controlled on medication areeligible.)

  • History of myocardial infarction documented by elevated cardiac enzymes or persistentregional wall abnormalities on assessment of LV function.

  • History of transient ischemic attack (TIA) or cerebrovascular accident (CVA).

  • History of other arterial thrombotic event within 12 months before study entry.

  • Symptomatic peripheral vascular disease.

  • Any significant non-traumatic bleeding within 6 months before study entry.

  • Serious or non-healing wound, skin ulcers, or incompletely healed bone fracture.

  • Gastroduodenal ulcer(s) determined by endoscopy to be active.

  • Invasive procedures defined as follows:

  • Major surgical procedure, open biopsy, or significant traumatic injury within 28days prior to planned start of study therapy. (Note: Placement of a vascularaccess device is not considered a major surgical procedure.)

  • Anticipation of need for major surgical procedures (other than the requiredbreast surgery) during the course of the study.

  • Known bleeding diathesis or coagulopathy. (Patients on warfarin with an in-rangeinternational normalized ratio [INR] [usually between 2 and 3] are eligible.)

  • Sensory/motor neuropathy greater than or equal grade 2, as defined by the NCI's CommonTerminology Criteria for Adverse Events Version 3.0 (CTCAE v3.0).

  • Other non-malignant systemic disease (cardiovascular, renal, hepatic, etc.) that wouldpreclude treatment with any of the treatment regimens or would prevent requiredfollow-up.

  • Conditions that would prohibit administration of corticosteroids.

  • History of severe hypersensitivity reaction to drugs formulated with polysorbate 80.

  • Administration of any investigational agents within 30 days before study entry.

  • Pregnancy or lactation at the time of proposed randomization.

Study Design

Total Participants: 1206
Study Start date:
November 01, 2006
Estimated Completion Date:
March 31, 2018

Study Description

OBJECTIVES:

Primary

  • Compare the efficacy of docetaxel followed by doxorubicin hydrocloride and cyclophosphamide (AC) vs docetaxel and capecitabine followed by AC vs docetaxel and gemcitabine hydrochloride followed by AC, with or without bevacizumab, in terms of an increase in the rate of pathologic complete response (pCR) in the breast, in women with palpable or operable breast cancer.

Secondary

  • Compare docetaxel/capecitabine with AC vs docetaxel/gemcitabine hydrochloride with AC vs docetaxel with AC, with or without bevacizumab, in terms of the rate of pCR in the breast and all post-therapy lymph nodes evaluated histologically (pCR breast and nodes).

  • Determine whether the addition of bevacizumab to the docetaxel/anthracycline-based regimens (docetaxel with AC, docetaxel and capecitabine with AC, and docetaxel and gemcitabine hydrochloride with AC) will increase the rate of pCR of the breast and nodes compared to the same docetaxel/anthracycline-based regimens without bevacizumab in these patients.

  • Determine whether the addition of capecitabine or gemcitabine hydrochloride to docetaxel, with or without bevacizumab, will increase the rate of clinical overall response (cOR) compared to docetaxel alone with or without bevacizumab in these patients.

  • Determine whether the addition of bevacizumab to the docetaxel/anthracycline-based regimens will increase the rate of cOR compared to the same docetaxel/anthracycline-based regimens without bevacizumab in these patients.

  • Determine whether the addition of capecitabine or gemcitabine hydrochloride to docetaxel, with or without bevacizumab, will increase the rate of clinical complete response (cCR) compared to docetaxel alone with or without bevacizumab in these patients.

  • Determine whether the addition of bevacizumab to the docetaxel/anthracycline-based regimens (docetaxel with AC, docetaxel/capecitabine with AC, and docetaxel/gemcitabine hydrochloride with AC) will increase the rate of cCR compared to the same docetaxel/anthracycline-based regimens without bevacizumab in these patients.

  • Identify gene expression profiles that can predict pCR in patients treated with the different sequential docetaxel/anthracycline-based regimens with or without bevacizumab.

  • Identify gene expression profiles that can predict cOR in patients treated with docetaxel alone, docetaxel/capecitabine, or docetaxel/gemcitabine hydrochloride with or without bevacizumab.

  • Determine the accuracy of an in vitro chemoresponse assay (ChemoFx®) as a predictor of pCR in patients treated with the different sequential docetaxel/anthracycline-based regimens without bevacizumab.

  • Determine the accuracy of ChemoFx® as a predictor of cOR in patients treated with docetaxel alone, docetaxel/capecitabine, or docetaxel/gemcitabine hydrochloride without bevacizumab in these patients.

  • Determine the impact of preoperative bevacizumab and sequential chemotherapy regimens and postoperative bevacizumab therapy on cardiac function in these patients.

  • Determine the impact of bevacizumab on surgical complications in these patients.

  • Determine the toxicity of the preoperative regimens and the toxicity of postoperative bevacizumab in these patients.

  • Compare the docetaxel/anthracycline-based regimens with vs without bevacizumab, in terms of an increase in disease-free survival, of these patients.

OUTLINE: This is a randomized, multicenter study. Patients are stratified according to tumor size (2-4 cm vs > 4 cm), nodal status (negative vs positive), hormone receptor status (estrogen receptor [ER]-positive and/or progesterone-receptor [PgR]-positive vs ER- and PgR-negative), and age (< 50 years vs ≥ 50 years). Patients are randomized to 1 of 6 treatment arms.

Core needle biopsies are performed at baseline. Tumor tissue samples are also collected during definitive surgery. Samples are examined for gene expression and polymorphism by reverse transcriptase-polymerase chain reaction analysis and chemoresponse assay (ChemoFx®).

After completion of study therapy, patients are followed periodically for 10 years.

PROJECTED ACCRUAL: A total of 1,200 patients will be accrued for this study.

Connect with a study center

  • Edmond Odette Cancer Centre at Sunnybrook

    Toronto, Ontario M4N 3M5
    Canada

    Site Not Available

  • CHUM - Hopital Saint-Luc

    Montreal, Quebec H2X 3J4
    Canada

    Site Not Available

  • CHUM - Hotel Dieu Hospital

    Montreal, Quebec H2W 1T8
    Canada

    Site Not Available

  • Hopital Notre-Dame du CHUM

    Montreal, Quebec H2L 4M1
    Canada

    Site Not Available

  • Jewish General Hospital - Montreal

    Montreal, Quebec H3T 1E2
    Canada

    Site Not Available

  • Montreal General Hospital

    Montreal, Quebec H3G 1A4
    Canada

    Site Not Available

  • Royal Victoria Hospital - Montreal

    Montreal, Quebec H3A 1A1
    Canada

    Site Not Available

  • St. Mary's Hospital Center

    Montreal, Quebec H3T 1M5
    Canada

    Site Not Available

  • Hopital du Saint-Sacrement - Quebec

    Quebec City, Quebec G1S 4L8
    Canada

    Site Not Available

  • San Juan City Hospital

    San Juan, 00928
    Puerto Rico

    Site Not Available

  • Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

    Little Rock, Arkansas 72205
    United States

    Site Not Available

  • East Bay Radiation Oncology Center

    Castro Valley, California 94546
    United States

    Site Not Available

  • Eden Medical Center

    Castro Valley, California 94546
    United States

    Site Not Available

  • Valley Medical Oncology Consultants - Castro Valley

    Castro Valley, California 94546
    United States

    Site Not Available

  • Kaiser Permanente - Fremont

    Fremont, California 94538
    United States

    Site Not Available

  • Valley Medical Oncology

    Fremont, California 94538
    United States

    Site Not Available

  • Cancer Care Associates

    Fresno, California 93720
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Hayward

    Hayward, California 94545
    United States

    Site Not Available

  • Scripps Cancer Center - San Diego

    La Jolla, California 92037
    United States

    Site Not Available

  • Loma Linda University Cancer Institute at Loma Linda University Medical Center

    Loma Linda, California 92354
    United States

    Site Not Available

  • Contra Costa Regional Medical Center

    Martinez, California 94553-3156
    United States

    Site Not Available

  • El Camino Hospital Cancer Center

    Mountain View, California 94040
    United States

    Site Not Available

  • Alta Bates Summit Medical Center - Summit Campus

    Oakland, California 94609
    United States

    Site Not Available

  • Bay Area Breast Surgeons, Incorporated

    Oakland, California 94609
    United States

    Site Not Available

  • CCOP - Bay Area Tumor Institute

    Oakland, California 94609
    United States

    Site Not Available

  • Highland General Hospital

    Oakland, California 94602
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Oakland

    Oakland, California 94611
    United States

    Site Not Available

  • Larry G Strieff MD Medical Corporation

    Oakland, California 94609
    United States

    Site Not Available

  • Tom K Lee, Incorporated

    Oakland, California 94609
    United States

    Site Not Available

  • St. Joseph Hospital Regional Cancer Center - Orange

    Orange, California 92868
    United States

    Site Not Available

  • Desert Regional Medical Center Comprehensive Cancer Center

    Palm Springs, California 92262
    United States

    Site Not Available

  • Valley Care Medical Center

    Pleasanton, California 94588
    United States

    Site Not Available

  • Valley Medical Oncology Consultants - Pleasanton

    Pleasanton, California 94588
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Redwood City

    Redwood City, California 94063
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Richmond

    Richmond, California 94801
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Roseville

    Roseville, California 95661
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Sacramento

    Sacramento, California 95825
    United States

    Site Not Available

  • South Sacramento Kaiser-Permanente Medical Center

    Sacramento, California 95823
    United States

    Site Not Available

  • Salinas Valley Memorial Hospital

    Salinas, California 93901
    United States

    Site Not Available

  • Kaiser Permanente Medical Office -Vandever Medical Office

    San Diego, California 92120
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - San Francisco Geary Campus

    San Francisco, California 94115
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Santa Teresa

    San Jose, California 95119
    United States

    Site Not Available

  • Doctors Medical Center - San Pablo Campus

    San Pablo, California 94806
    United States

    Site Not Available

  • Kaiser Foundation Hospital - San Rafael

    San Rafael, California 94903
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Santa Clara Kiely Campus

    Santa Clara, California 95051
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Santa Rosa

    Santa Rosa, California 95403
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - South San Francisco

    South San Francisco, California 94080
    United States

    Site Not Available

  • Kaiser Permanente Medical Facility - Stockton

    Stockton, California 95210
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Vallejo

    Vallejo, California 94589
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Walnut Creek

    Walnut Creek, California 94596
    United States

    Site Not Available

  • Aurora Presbyterian Hospital

    Aurora, Colorado 80012
    United States

    Site Not Available

  • Boulder Community Hospital

    Boulder, Colorado 80301-9019
    United States

    Site Not Available

  • Memorial Hospital Cancer Center - Colorado Springs

    Colorado Springs, Colorado 80909
    United States

    Site Not Available

  • Penrose Cancer Center at Penrose Hospital

    Colorado Springs, Colorado 80933
    United States

    Site Not Available

  • CCOP - Colorado Cancer Research Program

    Denver, Colorado 80224-2522
    United States

    Site Not Available

  • Kaiser Permanente - Denver

    Denver, Colorado 80205
    United States

    Site Not Available

  • Porter Adventist Hospital

    Denver, Colorado 80210
    United States

    Site Not Available

  • Presbyterian - St. Luke's Medical Center

    Denver, Colorado 80218
    United States

    Site Not Available

  • Rose Medical Center

    Denver, Colorado 80220
    United States

    Site Not Available

  • St. Anthony Central Hospital

    Denver, Colorado 80204
    United States

    Site Not Available

  • St. Joseph Hospital

    Denver, Colorado 80218
    United States

    Site Not Available

  • Swedish Medical Center

    Englewood, Colorado 80110
    United States

    Site Not Available

  • St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center

    Grand Junction, Colorado 81502
    United States

    Site Not Available

  • North Colorado Medical Center

    Greeley, Colorado 80631
    United States

    Site Not Available

  • Kaiser Permanente - Lafayette

    Lafayette, Colorado 80026
    United States

    Site Not Available

  • Sky Ridge Medical Center

    Lone Tree, Colorado 80124
    United States

    Site Not Available

  • Hope Cancer Care Center at Longmont United Hospital

    Longmont, Colorado 80501
    United States

    Site Not Available

  • McKee Medical Center

    Loveland, Colorado 80539
    United States

    Site Not Available

  • St. Mary - Corwin Regional Medical Center

    Pueblo, Colorado 81004
    United States

    Site Not Available

  • North Suburban Medical Center

    Thornton, Colorado 80229
    United States

    Site Not Available

  • Exempla Lutheran Medical Center

    Wheat Ridge, Colorado 80033
    United States

    Site Not Available

  • Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center

    Farmington, Connecticut 06360-2875
    United States

    Site Not Available

  • Helen and Harry Gray Cancer Center at Hartford Hospital

    Hartford, Connecticut 06102-5037
    United States

    Site Not Available

  • Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

    Hartford, Connecticut 06105
    United States

    Site Not Available

  • Eastern Connecticut Hematology and Oncology Associates

    Norwich, Connecticut 06360
    United States

    Site Not Available

  • Tunnell Cancer Center at Beebe Medical Center

    Lewes, Delaware 19958
    United States

    Site Not Available

  • CCOP - Christiana Care Health Services

    Newark, Delaware 19713
    United States

    Site Not Available

  • Sibley Memorial Hospital

    Washington, D.C., District of Columbia 20016
    United States

    Site Not Available

  • Herbert D. Kerman Regional Oncology Center - Daytona Beach

    Daytona Beach, Florida 32114
    United States

    Site Not Available

  • Broward General Medical Center Cancer Center

    Fort Lauderdale, Florida 33316
    United States

    Site Not Available

  • Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital

    Fort Lauderdale, Florida 33308
    United States

    Site Not Available

  • Baptist Cancer Institute - Jacksonville

    Jacksonville, Florida 32207
    United States

    Site Not Available

  • Ella Milbank Foshay Cancer Center at Jupiter Medical Center

    Jupiter, Florida 33458
    United States

    Site Not Available

  • CCOP - Mount Sinai Medical Center

    Miami Beach, Florida 33140
    United States

    Site Not Available

  • Florida Hospital Cancer Institute at Florida Hospital Orlando

    Orlando, Florida 32803-1273
    United States

    Site Not Available

  • M.D. Anderson Cancer Center at Orlando

    Orlando, Florida 32806
    United States

    Site Not Available

  • Phoebe Cancer Center at Phoebe Putney Memorial Hospital

    Albany, Georgia 31701
    United States

    Site Not Available

  • Northeast Georgia Medical Center

    Gainesville, Georgia 30501
    United States

    Site Not Available

  • Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

    Savannah, Georgia 31403-3089
    United States

    Site Not Available

  • Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

    Savannah, Georgia 31405
    United States

    Site Not Available

  • Kapiolani Medical Center at Pali Momi

    'Aiea, Hawaii 96701
    United States

    Site Not Available

  • Kapiolani Medical Center at Pali Momi

    Aiea, Hawaii 96701
    United States

    Site Not Available

  • Cancer Research Center of Hawaii

    Honolulu, Hawaii 96813
    United States

    Site Not Available

  • Hawaii Medical Center - East

    Honolulu, Hawaii 96817
    United States

    Site Not Available

  • Kaiser Permanente - Moanalua Medical Center and Clinic

    Honolulu, Hawaii 96819
    United States

    Site Not Available

  • Kapiolani Medical Center for Women and Children

    Honolulu, Hawaii 96826
    United States

    Site Not Available

  • OnCare Hawaii, Incorporated - Kuakini

    Honolulu, Hawaii 96817
    United States

    Site Not Available

  • OnCare Hawaii, Incorporated - Lusitana

    Honolulu, Hawaii 96813
    United States

    Site Not Available

  • Queen's Cancer Institute at Queen's Medical Center

    Honolulu, Hawaii 96813
    United States

    Site Not Available

  • Straub Clinic and Hospital, Incorporated

    Honolulu, Hawaii 96813
    United States

    Site Not Available

  • Maui Memorial Medical Center

    Wailuku, Hawaii 96793
    United States

    Site Not Available

  • Pacific Cancer Institute - Maui

    Wailuku, Hawaii 96793
    United States

    Site Not Available

  • Kootenai Cancer Center - Coeur d'Alene

    Coeur d'Alene, Idaho 83814
    United States

    Site Not Available

  • Saint Anthony's Hospital at Saint Anthony's Health Center

    Alton, Illinois 62002
    United States

    Site Not Available

  • Illinois CancerCare - Bloomington

    Bloomington, Illinois 61701
    United States

    Site Not Available

  • St. Joseph Medical Center

    Bloomington, Illinois 61701
    United States

    Site Not Available

  • Illinois CancerCare - Bloomington

    Bloomington%, Illinois 61701
    United States

    Site Not Available

  • Graham Hospital

    Canton, Illinois 61520
    United States

    Site Not Available

  • Illinois CancerCare - Canton

    Canton, Illinois 61520
    United States

    Site Not Available

  • Illinois CancerCare - Carthage

    Carthage, Illinois 62321
    United States

    Site Not Available

  • Memorial Hospital

    Carthage, Illinois 62321
    United States

    Site Not Available

  • John H. Stroger, Jr. Hospital of Cook County

    Chicago, Illinois 60612-3785
    United States

    Site Not Available

  • Mount Sinai Hospital Medical Center

    Chicago, Illinois 60608
    United States

    Site Not Available

  • Rush University Medical Center

    Chicago, Illinois 60612
    United States

    Site Not Available

  • Decatur Memorial Hospital Cancer Care Institute

    Decatur, Illinois 62526
    United States

    Site Not Available

  • Alexian Brothers Radiation Oncology

    Elk Grove Village, Illinois 60007
    United States

    Site Not Available

  • Eureka Community Hospital

    Eureka, Illinois 61530
    United States

    Site Not Available

  • Illinois CancerCare - Eureka

    Eureka, Illinois 61530
    United States

    Site Not Available

  • St. Francis Hospital

    Evanston, Illinois 60202
    United States

    Site Not Available

  • Galesburg Clinic, PC

    Galesburg, Illinois 61401
    United States

    Site Not Available

  • Galesburg Cottage Hospital

    Galesburg, Illinois 61401
    United States

    Site Not Available

  • Illinois CancerCare - Cottage

    Galesburg, Illinois 61401
    United States

    Site Not Available

  • Illinois CancerCare - Galesburg

    Galesburg, Illinois 61401
    United States

    Site Not Available

  • Illinois CancerCare - Havana

    Havana, Illinois 62644
    United States

    Site Not Available

  • Mason District Hospital

    Havana, Illinois 62644
    United States

    Site Not Available

  • Illinois CancerCare - Kewanee Clinic

    Kewanee, Illinois 61443
    United States

    Site Not Available

  • Illinois CancerCare - Macomb

    Macomb, Illinois 61455
    United States

    Site Not Available

  • McDonough District Hospital

    Macomb, Illinois 61455
    United States

    Site Not Available

  • Cardinal Bernardin Cancer Center at Loyola University Medical Center

    Maywood, Illinois 60153
    United States

    Site Not Available

  • Illinois CancerCare - Monmouth

    Monmouth, Illinois 61462
    United States

    Site Not Available

  • OSF Holy Family Medical Center

    Monmouth, Illinois 61462
    United States

    Site Not Available

  • Good Samaritan Regional Health Center

    Mount Vernon, Illinois 62864
    United States

    Site Not Available

  • Good Samaritan Regional Health Center

    Mt. Vernon, Illinois 62864
    United States

    Site Not Available

  • Edward Hospital Cancer Center

    Naperville, Illinois 60540
    United States

    Site Not Available

  • BroMenn Regional Medical Center

    Normal, Illinois 61761
    United States

    Site Not Available

  • Community Cancer Center

    Normal, Illinois 61761
    United States

    Site Not Available

  • Illinois CancerCare - Community Cancer Center

    Normal, Illinois 61761
    United States

    Site Not Available

  • Community Hospital of Ottawa

    Ottawa, Illinois 61350
    United States

    Site Not Available

  • Oncology Hematology Associates of Central Illinois, PC - Ottawa

    Ottawa, Illinois 61350
    United States

    Site Not Available

  • Illinois CancerCare - Pekin

    Pekin, Illinois 61603
    United States

    Site Not Available

  • CCOP - Illinois Oncology Research Association

    Peoria, Illinois 61615
    United States

    Site Not Available

  • Methodist Medical Center of Illinois

    Peoria, Illinois 61636
    United States

    Site Not Available

  • OSF St. Francis Medical Center

    Peoria, Illinois 61637
    United States

    Site Not Available

  • Oncology Hematology Associates of Central Illinois, PC - Peoria

    Peoria, Illinois 61615
    United States

    Site Not Available

  • Proctor Hospital

    Peoria, Illinois 61614
    United States

    Site Not Available

  • Illinois CancerCare - Peru

    Peru, Illinois 61354
    United States

    Site Not Available

  • Illinois Valley Community Hospital

    Peru, Illinois 61354
    United States

    Site Not Available

  • Illinois CancerCare - Princeton

    Princeton, Illinois 61356
    United States

    Site Not Available

  • Perry Memorial Hospital

    Princeton, Illinois 61356
    United States

    Site Not Available

  • Swedish-American Regional Cancer Center

    Rockford, Illinois 61104-2315
    United States

    Site Not Available

  • Illinois CancerCare - Spring Valley

    Spring Valley, Illinois 61362
    United States

    Site Not Available

  • Regional Cancer Center at Memorial Medical Center

    Springfield, Illinois 62781-0001
    United States

    Site Not Available

  • St. Francis Hospital and Health Centers - Beech Grove Campus

    Beech Grove, Indiana 46107
    United States

    Site Not Available

  • Elkhart Clinic, LLC

    Elkhart, Indiana 46514-2098
    United States

    Site Not Available

  • Elkhart General Hospital

    Elkhart, Indiana 46515
    United States

    Site Not Available

  • Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indiana 46845
    United States

    Site Not Available

  • Center for Cancer Care at Goshen General Hospital

    Goshen, Indiana 46526
    United States

    Site Not Available

  • St. Vincent Indianapolis Hospital

    Indianapolis, Indiana 46260
    United States

    Site Not Available

  • Howard Community Hospital

    Kokomo, Indiana 46904
    United States

    Site Not Available

  • Center for Cancer Therapy at LaPorte Hospital and Health Services

    La Porte, Indiana 46350
    United States

    Site Not Available

  • Community Hospital

    Munster, Indiana 46321
    United States

    Site Not Available

  • Reid Hospital & Health Care Services

    Richmond, Indiana 47374
    United States

    Site Not Available

  • CCOP - Northern Indiana CR Consortium

    South Bend, Indiana 46601
    United States

    Site Not Available

  • Memorial Hospital of South Bend

    South Bend, Indiana 46601
    United States

    Site Not Available

  • Michiana Hematology-Oncology, PC - South Bend

    South Bend, Indiana 46601
    United States

    Site Not Available

  • Saint Joseph Regional Medical Center

    South Bend, Indiana 46617
    United States

    Site Not Available

  • South Bend Clinic

    South Bend, Indiana 46617
    United States

    Site Not Available

  • McFarland Clinic, PC

    Ames, Iowa 50010
    United States

    Site Not Available

  • Holden Comprehensive Cancer Center at University of Iowa

    Iowa City, Iowa 52242-1002
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Chanute

    Chanute, Kansas 66720
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Dodge City

    Dodge City, Kansas 67801
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - El Dorado

    El Dorado, Kansas 67042
    United States

    Site Not Available

  • Cancer Center of Kansas - Fort Scott

    Fort Scott, Kansas 66701
    United States

    Site Not Available

  • Cancer Center of Kansas-Independence

    Independence, Kansas 67301
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Kingman

    Kingman, Kansas 67068
    United States

    Site Not Available

  • Lawrence Memorial Hospital

    Lawrence, Kansas 66044
    United States

    Site Not Available

  • Southwest Medical Center

    Liberal, Kansas 67901
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Newton

    Newton, Kansas 67114
    United States

    Site Not Available

  • Menorah Medical Center

    Overland Park, Kansas 66209
    United States

    Site Not Available

  • Saint Luke's Hospital - South

    Overland Park, Kansas 66213
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Parsons

    Parsons, Kansas 67357
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Pratt

    Pratt, Kansas 67124
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Salina

    Salina, Kansas 67401
    United States

    Site Not Available

  • Shawnee Mission Medical Center

    Shawnee, Kansas 66204
    United States

    Site Not Available

  • Shawnee Mission Medical Center

    Shawnee Mission, Kansas 66204
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Wellington

    Wellington, Kansas 67152
    United States

    Site Not Available

  • Associates in Womens Health, PA - North Review

    Wichita, Kansas 67208
    United States

    Site Not Available

  • CCOP - Wichita

    Wichita, Kansas 67214
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Medical Arts Tower

    Wichita, Kansas 67208
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Wichita

    Wichita, Kansas 67214
    United States

    Site Not Available

  • Via Christi Cancer Center at Via Christi Regional Medical Center

    Wichita, Kansas 67214
    United States

    Site Not Available

  • Wesley Medical Center

    Wichita, Kansas 67214
    United States

    Site Not Available

  • Cancer Center of Kansas, PA - Winfield

    Winfield, Kansas 67156
    United States

    Site Not Available

  • Cancer Resource Center at King's Daughters Medical Center

    Ashland, Kentucky 41101-0151
    United States

    Site Not Available

  • Lucille P. Markey Cancer Center at University of Kentucky

    Lexington, Kentucky 40536-0093
    United States

    Site Not Available

  • James Graham Brown Cancer Center at University of Louisville

    Louisville, Kentucky 40292
    United States

    Site Not Available

  • Louisville Oncology at Norton Cancer Institute - Louisville

    Louisville, Kentucky 40202
    United States

    Site Not Available

  • Mary Bird Perkins Cancer Center - Baton Rouge

    Baton Rouge, Louisiana 70809
    United States

    Site Not Available

  • Ochsner Health Center - Bluebonnet

    Baton Rouge, Louisiana 70809
    United States

    Site Not Available

  • CCOP - Ochsner

    New Orleans, Louisiana 70121
    United States

    Site Not Available

  • MBCCOP - LSU Health Sciences Center

    New Orleans, Louisiana 70112
    United States

    Site Not Available

  • Medical Center of Louisiana - New Orleans

    New Orleans, Louisiana 70112
    United States

    Site Not Available

  • Ochsner Cancer Institute at Ochsner Clinic Foundation

    New Orleans, Louisiana 70121
    United States

    Site Not Available

  • York Hospital's Oncology Treatment Center

    York, Maine 03909
    United States

    Site Not Available

  • Greater Baltimore Medical Center Cancer Center

    Baltimore, Maryland 21204
    United States

    Site Not Available

  • Greenebaum Cancer Center at University of Maryland Medical Center

    Baltimore, Maryland 21201
    United States

    Site Not Available

  • Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center

    Baltimore, Maryland 21237
    United States

    Site Not Available

  • St. Agnes Hospital Cancer Center

    Baltimore, Maryland 21229
    United States

    Site Not Available

  • Frederick Memorial Hospital Regional Cancer Therapy Center

    Frederick, Maryland 21701
    United States

    Site Not Available

  • Associates in Oncology and Hematology - Medical Center Drive

    Rockville, Maryland 20878
    United States

    Site Not Available

  • Peninsula Regional Medical Center

    Salisbury, Maryland 21801
    United States

    Site Not Available

  • MetroWest Medical Center - Framingham Union Hospital

    Framingham, Massachusetts 01702
    United States

    Site Not Available

  • Hickman Cancer Center at Bixby Medical Center

    Adrian, Michigan 49221
    United States

    Site Not Available

  • CCOP - Michigan Cancer Research Consortium

    Ann Arbor, Michigan 48106
    United States

    Site Not Available

  • Saint Joseph Mercy Cancer Center

    Ann Arbor, Michigan 48106-0995
    United States

    Site Not Available

  • Oakwood Cancer Center at Oakwood Hospital and Medical Center

    Dearborn, Michigan 48123-2500
    United States

    Site Not Available

  • Josephine Ford Cancer Center at Henry Ford Hospital

    Detroit, Michigan 48202
    United States

    Site Not Available

  • Genesys Hurley Cancer Institute

    Flint, Michigan 48503
    United States

    Site Not Available

  • Great Lakes Cancer Institute at McLaren Regional Medical Center

    Flint, Michigan 48532
    United States

    Site Not Available

  • Hurley Medical Center

    Flint, Michigan 48503
    United States

    Site Not Available

  • Van Elslander Cancer Center at St. John Hospital and Medical Center

    Grosse Pointe Woods, Michigan 48236
    United States

    Site Not Available

  • Foote Memorial Hospital

    Jackson, Michigan 49201
    United States

    Site Not Available

  • Borgess Medical Center

    Kalamazoo, Michigan 49001
    United States

    Site Not Available

  • Bronson Methodist Hospital

    Kalamazoo, Michigan 49007
    United States

    Site Not Available

  • West Michigan Cancer Center

    Kalamazoo, Michigan 49007-3731
    United States

    Site Not Available

  • Haematology-Oncology Associates of Ohio and Michigan, PC

    Lambertville, Michigan 48144
    United States

    Site Not Available

  • Breslin Cancer Center at Ingham Regional Medical Center

    Lansing, Michigan 48910
    United States

    Site Not Available

  • Sparrow Regional Cancer Center

    Lansing, Michigan 48912-1811
    United States

    Site Not Available

  • Lapeer Regional Hospital

    Lapeer, Michigan 48446
    United States

    Site Not Available

  • St. Mary Mercy Hospital

    Livonia, Michigan 48154
    United States

    Site Not Available

  • Community Cancer Center of Monroe

    Monroe, Michigan 48162
    United States

    Site Not Available

  • Mercy Memorial Hospital - Monroe

    Monroe, Michigan 48162
    United States

    Site Not Available

  • St. Joseph Mercy Oakland

    Pontiac, Michigan 48341-2985
    United States

    Site Not Available

  • Mercy Regional Cancer Center at Mercy Hospital

    Port Huron, Michigan 48060
    United States

    Site Not Available

  • Seton Cancer Institute at Saint Mary's - Saginaw

    Saginaw, Michigan 48601
    United States

    Site Not Available

  • Lakeland Regional Cancer Care Center - St. Joseph

    Saint Joseph, Michigan 49085
    United States

    Site Not Available

  • Lakeside Cancer Specialists, PLLC

    Saint Joseph, Michigan 49085
    United States

    Site Not Available

  • Providence Cancer Institute at Providence Hospital - Southfield Campus

    Southfield, Michigan 48075
    United States

    Site Not Available

  • Lakeland Regional Cancer Care Center - St. Joseph

    St. Joseph, Michigan 49085
    United States

    Site Not Available

  • St. John Macomb Hospital

    Warren, Michigan 48093
    United States

    Site Not Available

  • Fairview Ridges Hospital

    Burnsville, Minnesota 55337
    United States

    Site Not Available

  • Mercy and Unity Cancer Center at Mercy Hospital

    Coon Rapids, Minnesota 55433
    United States

    Site Not Available

  • CCOP - Duluth

    Duluth, Minnesota 55805
    United States

    Site Not Available

  • Duluth Clinic Cancer Center - Duluth

    Duluth, Minnesota 55805-1983
    United States

    Site Not Available

  • Miller - Dwan Medical Center

    Duluth, Minnesota 55805
    United States

    Site Not Available

  • Fairview Southdale Hospital

    Edina, Minnesota 55435
    United States

    Site Not Available

  • Mercy and Unity Cancer Center at Unity Hospital

    Fridley, Minnesota 55432
    United States

    Site Not Available

  • Hutchinson Area Health Care

    Hutchinson, Minnesota 55350
    United States

    Site Not Available

  • HealthEast Cancer Care at St. John's Hospital

    Maplewood, Minnesota 55109
    United States

    Site Not Available

  • Minnesota Oncology Hematology, PA - Maplewood

    Maplewood, Minnesota 55109
    United States

    Site Not Available

  • Hennepin County Medical Center - Minneapolis

    Minneapolis, Minnesota 55415
    United States

    Site Not Available

  • Virginia Piper Cancer Institute at Abbott - Northwestern Hospital

    Minneapolis, Minnesota 55407
    United States

    Site Not Available

  • Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center

    Robbinsdale, Minnesota 55422-2900
    United States

    Site Not Available

  • CCOP - Metro-Minnesota

    Saint Louis Park, Minnesota 55416
    United States

    Site Not Available

  • Park Nicollet Cancer Center

    Saint Louis Park, Minnesota 55416
    United States

    Site Not Available

  • Regions Hospital Cancer Care Center

    Saint Paul, Minnesota 55101
    United States

    Site Not Available

  • United Hospital

    Saint Paul, Minnesota 55102
    United States

    Site Not Available

  • St. Francis Cancer Center at St. Francis Medical Center

    Shakopee, Minnesota 55379
    United States

    Site Not Available

  • Regions Hospital Cancer Care Center

    St. Paul, Minnesota 55101
    United States

    Site Not Available

  • Ridgeview Medical Center

    Waconia, Minnesota 55387
    United States

    Site Not Available

  • Minnesota Oncology Hematology, PA - Woodbury

    Woodbury, Minnesota 55125
    United States

    Site Not Available

  • Hattiesburg Clinic, PA at Forrest General

    Hattiesburg, Mississippi 39401
    United States

    Site Not Available

  • Saint Francis Medical Center

    Cape Girardeau, Missouri 63703
    United States

    Site Not Available

  • Ellis Fischel Cancer Center at University of Missouri - Columbia

    Columbia, Missouri 65203
    United States

    Site Not Available

  • St. John's Regional Medical Center

    Joplin, Missouri 64804
    United States

    Site Not Available

  • CCOP - Kansas City

    Kansas City, Missouri 64131
    United States

    Site Not Available

  • Heartland Hematology Oncology Associates, Incorporated

    Kansas City, Missouri 64118
    United States

    Site Not Available

  • North Kansas City Hospital

    Kansas City, Missouri 64116
    United States

    Site Not Available

  • Parvin Radiation Oncology

    Kansas City, Missouri 64116
    United States

    Site Not Available

  • Research Medical Center

    Kansas City, Missouri 64132
    United States

    Site Not Available

  • Saint Luke's Cancer Institute at Saint Luke's Hospital

    Kansas City, Missouri 64111
    United States

    Site Not Available

  • St. Joseph Medical Center

    Kansas City, Missouri 64114
    United States

    Site Not Available

  • Truman Medical Center - Hospital Hill

    Kansas City, Missouri 64108
    United States

    Site Not Available

  • Saint Luke's East - Lee's Summit

    Lee's Summit, Missouri 64086
    United States

    Site Not Available

  • Liberty Hospital

    Liberty, Missouri 64068
    United States

    Site Not Available

  • Heartland Regional Medical Center

    Saint Joseph, Missouri 64506
    United States

    Site Not Available

  • CCOP - St. Louis-Cape Girardeau

    Saint Louis, Missouri 63141
    United States

    Site Not Available

  • David C. Pratt Cancer Center at St. John's Mercy

    Saint Louis, Missouri 63141
    United States

    Site Not Available

  • Midwest Hematology Oncology Group, Incorporated

    Saint Louis, Missouri 63109
    United States

    Site Not Available

  • Saint Louis University Cancer Center

    Saint Louis, Missouri 63110
    United States

    Site Not Available

  • CCOP - Cancer Research for the Ozarks

    Springfield, Missouri 65802
    United States

    Site Not Available

  • Hulston Cancer Center at Cox Medical Center South

    Springfield, Missouri 65807
    United States

    Site Not Available

  • St. John's Regional Health Center

    Springfield, Missouri 65804
    United States

    Site Not Available

  • Billings Clinic - Downtown

    Billings, Montana 59107-7000
    United States

    Site Not Available

  • CCOP - Montana Cancer Consortium

    Billings, Montana 59101
    United States

    Site Not Available

  • Hematology-Oncology Centers of the Northern Rockies - Billings

    Billings, Montana 59101
    United States

    Site Not Available

  • Northern Rockies Radiation Oncology Center

    Billings, Montana 59101
    United States

    Site Not Available

  • St. Vincent Healthcare Cancer Care Services

    Billings, Montana 59101
    United States

    Site Not Available

  • Bozeman Deaconess Cancer Center

    Bozeman, Montana 59715
    United States

    Site Not Available

  • St. James Healthcare Cancer Care

    Butte, Montana 59701
    United States

    Site Not Available

  • Big Sky Oncology

    Great Falls, Montana 59405-5309
    United States

    Site Not Available

  • Great Falls Clinic - Main Facility

    Great Falls, Montana 59405
    United States

    Site Not Available

  • Sletten Cancer Institute at Benefis Healthcare

    Great Falls, Montana 59405
    United States

    Site Not Available

  • Great Falls, Montana 59405
    United States

    Site Not Available

  • St. Peter's Hospital

    Helena, Montana 59601
    United States

    Site Not Available

  • Glacier Oncology, PLLC

    Kalispell, Montana 59901
    United States

    Site Not Available

  • Kalispell Medical Oncology at KRMC

    Kalispell, Montana 59901
    United States

    Site Not Available

  • Kalispell Regional Medical Center

    Kalispell, Montana 59901
    United States

    Site Not Available

  • Community Medical Center

    Missoula, Montana 59801
    United States

    Site Not Available

  • Guardian Oncology and Center for Wellness

    Missoula, Montana 59804
    United States

    Site Not Available

  • Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

    Missoula, Montana 59807
    United States

    Site Not Available

  • Montana Cancer Specialists at Montana Cancer Center

    Missoula, Montana 59807-7877
    United States

    Site Not Available

  • Good Samaritan Cancer Center at Good Samaritan Hospital

    Kearney, Nebraska 68848-1990
    United States

    Site Not Available

  • Cancer Resource Center - Lincoln

    Lincoln, Nebraska 68510
    United States

    Site Not Available

  • Alegant Health Cancer Center at Bergan Mercy Medical Center

    Omaha, Nebraska 68124
    United States

    Site Not Available

  • CCOP - Missouri Valley Cancer Consortium

    Omaha, Nebraska 68106
    United States

    Site Not Available

  • Creighton University Medical Center

    Omaha, Nebraska 68131-2197
    United States

    Site Not Available

  • Immanuel Medical Center

    Omaha, Nebraska 68122
    United States

    Site Not Available

  • Cancer Institute of New Jersey at Hamilton

    Hamilton, New Jersey 08690
    United States

    Site Not Available

  • Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School

    New Brunswick, New Jersey 08903
    United States

    Site Not Available

  • Newark Beth Israel Medical Center

    Newark, New Jersey 07112
    United States

    Site Not Available

  • Cancer Institute of New Jersey at Cooper - Voorhees

    Voorhees, New Jersey 08043
    United States

    Site Not Available

  • Our Lady of Mercy Medical Center Comprehensive Cancer Center

    Bronx, New York 10466
    United States

    Site Not Available

  • Charles R. Wood Cancer Center at Glens Falls Hospital

    Glens Falls, New York 12801
    United States

    Site Not Available

  • Tucker Center for Cancer Care at Orange Regional Medical Center

    Middletown, New York 10940-4199
    United States

    Site Not Available

  • Saint Francis Hospital Cancer Center

    Poughkeepsie, New York 12601
    United States

    Site Not Available

  • Our Lady of Mercy Medical Center Comprehensive Cancer Center

    The Bronx, New York 10466
    United States

    Site Not Available

  • Randolph Hospital

    Asheboro, North Carolina 27203-5400
    United States

    Site Not Available

  • Hope A Women's Cancer Center

    Asheville, North Carolina 28816
    United States

    Site Not Available

  • Alamance Cancer Center at Alamance Regional Medical Center

    Burlington, North Carolina 27216
    United States

    Site Not Available

  • Blumenthal Cancer Center at Carolinas Medical Center

    Charlotte, North Carolina 28232-2861
    United States

    Site Not Available

  • Presbyterian Cancer Center at Presbyterian Hospital

    Charlotte, North Carolina 28233-3549
    United States

    Site Not Available

  • Batte Cancer Center at Northeast Medical Center

    Concord, North Carolina 28025
    United States

    Site Not Available

  • Wayne Memorial Hospital, Incorporated

    Goldsboro, North Carolina 27534
    United States

    Site Not Available

  • Moses Cone Regional Cancer Center at Wesley Long Community Hospital

    Greensboro, North Carolina 27403-1198
    United States

    Site Not Available

  • Annie Penn Cancer Center

    Reidsville, North Carolina 27320
    United States

    Site Not Available

  • Rutherford Hospital

    Rutherfordton, North Carolina 28139
    United States

    Site Not Available

  • Iredell Memorial Hospital

    Statesville, North Carolina 28677
    United States

    Site Not Available

  • Marion L. Shepard Cancer Center at Beaufort County Hospital

    Washington, North Carolina 27889
    United States

    Site Not Available

  • Forsyth Regional Cancer Center at Forsyth Medical Center

    Winston-Salem, North Carolina 27103
    United States

    Site Not Available

  • Wake Forest University Comprehensive Cancer Center

    Winston-Salem, North Carolina 27157-1096
    United States

    Site Not Available

  • Altru Cancer Center at Altru Hospital

    Grand Forks, North Dakota 58201
    United States

    Site Not Available

  • McDowell Cancer Center at Akron General Medical Center

    Akron, Ohio 44307
    United States

    Site Not Available

  • Summa Center for Cancer Care at Akron City Hospital

    Akron, Ohio 44309-2090
    United States

    Site Not Available

  • Barberton Citizens Hospital

    Barberton, Ohio 44203
    United States

    Site Not Available

  • Wood County Oncology Center

    Bowling Green, Ohio 43402
    United States

    Site Not Available

  • Aultman Cancer Center at Aultman Hospital

    Canton, Ohio 44710-1799
    United States

    Site Not Available

  • Case Comprehensive Cancer Center

    Cleveland, Ohio 44106-5065
    United States

    Site Not Available

  • North Coast Cancer Care - Clyde

    Clyde, Ohio 43410
    United States

    Site Not Available

  • Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

    Columbus, Ohio 43210-1240
    United States

    Site Not Available

  • CCOP - Dayton

    Dayton, Ohio 45420
    United States

    Site Not Available

  • David L. Rike Cancer Center at Miami Valley Hospital

    Dayton, Ohio 45409
    United States

    Site Not Available

  • Good Samaritan Hospital

    Dayton, Ohio 45406
    United States

    Site Not Available

  • Grandview Hospital

    Dayton, Ohio 45405
    United States

    Site Not Available

  • Samaritan North Cancer Care Center

    Dayton, Ohio 45415
    United States

    Site Not Available

  • Community Cancer Center

    Elyria, Ohio 44035
    United States

    Site Not Available

  • Hematology Oncology Center

    Elyria, Ohio 44035
    United States

    Site Not Available

  • Blanchard Valley Medical Associates

    Findlay, Ohio 45840
    United States

    Site Not Available

  • Middletown Regional Hospital

    Franklin, Ohio 45005-1066
    United States

    Site Not Available

  • Wayne Hospital

    Greenville, Ohio 45331
    United States

    Site Not Available

  • Charles F. Kettering Memorial Hospital

    Kettering, Ohio 45429
    United States

    Site Not Available

  • Lima Memorial Hospital

    Lima, Ohio 45804
    United States

    Site Not Available

  • Northwest Ohio Oncology Center

    Maumee, Ohio 43537-1839
    United States

    Site Not Available

  • St. Luke's Hospital

    Maumee, Ohio 43537
    United States

    Site Not Available

  • Fisher-Titus Medical Center

    Norwalk, Ohio 44857
    United States

    Site Not Available

  • St. Charles Mercy Hospital

    Oregon, Ohio 43616
    United States

    Site Not Available

  • Toledo Clinic - Oregon

    Oregon, Ohio 43616
    United States

    Site Not Available

  • Cancer Care Center, Incorporated

    Salem, Ohio 44460
    United States

    Site Not Available

  • North Coast Cancer Care, Incorporated

    Sandusky, Ohio 44870
    United States

    Site Not Available

  • Flower Hospital Cancer Center

    Sylvania, Ohio 43560
    United States

    Site Not Available

  • Mercy Hospital of Tiffin

    Tiffin, Ohio 44883
    United States

    Site Not Available

  • CCOP - Toledo Community Hospital

    Toledo, Ohio 43617
    United States

    Site Not Available

  • Medical University of Ohio Cancer Center

    Toledo, Ohio 43614
    United States

    Site Not Available

  • St. Anne Mercy Hospital

    Toledo, Ohio 43623
    United States

    Site Not Available

  • St. Vincent Mercy Medical Center

    Toledo, Ohio 43608
    United States

    Site Not Available

  • Toledo Clinic, Incorporated - Main Clinic

    Toledo, Ohio 43623
    United States

    Site Not Available

  • Toledo Hospital

    Toledo, Ohio 43606
    United States

    Site Not Available

  • UVMC Cancer Care Center at Upper Valley Medical Center

    Troy, Ohio 45373-1300
    United States

    Site Not Available

  • Fulton County Health Center

    Wauseon, Ohio 43567
    United States

    Site Not Available

  • Clinton Memorial Hospital

    Wilmington, Ohio 45177
    United States

    Site Not Available

  • Cancer Treatment Center

    Wooster, Ohio 44691
    United States

    Site Not Available

  • Ruth G. McMillan Cancer Center at Greene Memorial Hospital

    Xenia, Ohio 45385
    United States

    Site Not Available

  • Cleo Craig Cancer Research Clinic

    Lawton, Oklahoma 73505
    United States

    Site Not Available

  • Kaiser Permanente Health Care - Portland

    Portland, Oregon 97232
    United States

    Site Not Available

  • Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest

    Allentown, Pennsylvania 18105
    United States

    Site Not Available

  • St. Luke's Cancer Network at St. Luke's Hospital

    Bethlehem, Pennsylvania 18015
    United States

    Site Not Available

  • Bryn Mawr Hospital

    Bryn Mawr, Pennsylvania 19010
    United States

    Site Not Available

  • Geisinger Cancer Institute at Geisinger Health

    Danville, Pennsylvania 17822-0001
    United States

    Site Not Available

  • Cherry Tree Cancer Center

    Hanover, Pennsylvania 17331
    United States

    Site Not Available

  • Penn State Cancer Institute at Milton S. Hershey Medical Center

    Hershey, Pennsylvania 17033-0850
    United States

    Site Not Available

  • Cancer Center of Paoli Memorial Hospital

    Paoli, Pennsylvania 19301-1792
    United States

    Site Not Available

  • Allegheny Cancer Center at Allegheny General Hospital

    Pittsburgh, Pennsylvania 15212
    United States

    Site Not Available

  • UPMC Cancer Centers

    Pittsburgh, Pennsylvania 15232
    United States

    Site Not Available

  • Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital

    Pittsburgh, Pennsylvania 15224-1791
    United States

    Site Not Available

  • McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

    Reading, Pennsylvania 19612-6052
    United States

    Site Not Available

  • Geisinger Medical Group - Scenery Park

    State College, Pennsylvania 16801
    United States

    Site Not Available

  • Mount Nittany Medical Center

    State College, Pennsylvania 16803
    United States

    Site Not Available

  • Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center

    Wilkes-Barre, Pennsylvania 18711
    United States

    Site Not Available

  • CCOP - Main Line Health

    Wynnewood, Pennsylvania 19096
    United States

    Site Not Available

  • Lankenau Cancer Center at Lankenau Hospital

    Wynnewood, Pennsylvania 19096
    United States

    Site Not Available

  • York Cancer Center at Apple Hill Medical Center

    York, Pennsylvania 17405
    United States

    Site Not Available

  • AnMed Cancer Center

    Anderson, South Carolina 29621
    United States

    Site Not Available

  • Hollings Cancer Center at Medical University of South Carolina

    Charleston, South Carolina 29425
    United States

    Site Not Available

  • Roper St. Francis Cancer Center at Roper Hospital

    Charleston, South Carolina 29401
    United States

    Site Not Available

  • CCOP - Greenville

    Greenville, South Carolina 29615
    United States

    Site Not Available

  • CCOP - Upstate Carolina

    Spartanburg, South Carolina 29303
    United States

    Site Not Available

  • Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

    Spartanburg, South Carolina 29303
    United States

    Site Not Available

  • Medical X-Ray Center, PC

    Sioux Falls, South Dakota 57105
    United States

    Site Not Available

  • Sanford Cancer Center at Sanford USD Medical Center

    Sioux Falls, South Dakota 57117-5039
    United States

    Site Not Available

  • Thompson Cancer Survival Center

    Knoxville, Tennessee 37916
    United States

    Site Not Available

  • University of Tennessee Cancer Institute - Memphis

    Memphis, Tennessee 38104
    United States

    Site Not Available

  • MBCCOP - Meharry Medical College - Nashville

    Nashville, Tennessee 37208-3599
    United States

    Site Not Available

  • Nashville Oncology Associates, PC

    Nashville, Tennessee 37203
    United States

    Site Not Available

  • Doctor's Hospital of Laredo

    Laredo, Texas 78041
    United States

    Site Not Available

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas 78229-3900
    United States

    Site Not Available

  • American Fork Hospital

    American Fork, Utah 84003
    United States

    Site Not Available

  • Sandra L. Maxwell Cancer Center

    Cedar City, Utah 84720
    United States

    Site Not Available

  • Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

    Murray, Utah 84157
    United States

    Site Not Available

  • Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

    Ogden, Utah 84403
    United States

    Site Not Available

  • Utah Valley Regional Medical Center - Provo

    Provo, Utah 84604
    United States

    Site Not Available

  • Dixie Regional Medical Center - East Campus

    Saint George, Utah 84770
    United States

    Site Not Available

  • Huntsman Cancer Institute at University of Utah

    Salt Lake City, Utah 84112
    United States

    Site Not Available

  • LDS Hospital

    Salt Lake City, Utah 84103
    United States

    Site Not Available

  • Utah Cancer Specialists at UCS Cancer Center

    Salt Lake City, Utah 84106
    United States

    Site Not Available

  • Mountainview Medical

    Berlin, Vermont 05602
    United States

    Site Not Available

  • Mountainview Medical

    Berlin Corners, Vermont 05602
    United States

    Site Not Available

  • Fletcher Allen Health Care - University Health Center Campus

    Burlington, Vermont 05401
    United States

    Site Not Available

  • Fredericksburg Oncology, Incorporated

    Fredericksburg, Virginia 22401
    United States

    Site Not Available

  • Virginia Commonwealth University Massey Cancer Center

    Richmond, Virginia 23298-0037
    United States

    Site Not Available

  • Auburn Regional Center for Cancer Care

    Auburn, Washington 98002
    United States

    Site Not Available

  • Providence Centralia Hospital

    Centralia, Washington 98531-9027
    United States

    Site Not Available

  • St. Francis Hospital

    Federal Way, Washington 98003
    United States

    Site Not Available

  • Providence St. Peter Hospital Regional Cancer Center

    Olympia, Washington 98506-5166
    United States

    Site Not Available

  • Good Samaritan Cancer Center

    Puyallup, Washington 98372
    United States

    Site Not Available

  • Allenmore Hospital

    Tacoma, Washington 98405
    United States

    Site Not Available

  • CCOP - Northwest

    Tacoma, Washington 98405
    United States

    Site Not Available

  • Franciscan Cancer Center at St. Joseph Medical Center

    Tacoma, Washington 98405-3004
    United States

    Site Not Available

  • MultiCare Regional Cancer Center at Tacoma General Hospital

    Tacoma, Washington 98405
    United States

    Site Not Available

  • St. Clare Hospital

    Tacoma, Washington 98499
    United States

    Site Not Available

  • West Virginia University Health Sciences Center - Charleston

    Charleston, West Virginia 25304
    United States

    Site Not Available

  • Mary Babb Randolph Cancer Center at West Virginia University Hospitals

    Morgantown, West Virginia 26506
    United States

    Site Not Available

  • Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital

    Parkersburg, West Virginia 26102
    United States

    Site Not Available

  • Marshfield Clinic - Chippewa Center

    Chippewa Falls, Wisconsin 54729
    United States

    Site Not Available

  • Marshfield Clinic Cancer Care at Regional Cancer Center

    Eau Claire, Wisconsin 54701
    United States

    Site Not Available

  • Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

    Green Bay, Wisconsin 54311
    United States

    Site Not Available

  • Gundersen Lutheran Center for Cancer and Blood

    La Crosse, Wisconsin 54601
    United States

    Site Not Available

  • Marshfield Clinic - Marshfield Center

    Marshfield, Wisconsin 54449
    United States

    Site Not Available

  • Saint Joseph's Hospital

    Marshfield, Wisconsin 54449
    United States

    Site Not Available

  • Aurora Sinai Medical Center

    Milwaukee, Wisconsin 53201-0342
    United States

    Site Not Available

  • Medical College of Wisconsin Cancer Center

    Milwaukee, Wisconsin 53226
    United States

    Site Not Available

  • Marshfield Clinic - Lakeland Center

    Minocqua, Wisconsin 54548
    United States

    Site Not Available

  • Vince Lombardi Cancer Clinic - Oshkosh

    Oshkosh, Wisconsin 54904
    United States

    Site Not Available

  • Ministry Medical Group at Saint Mary's Hospital

    Rhinelander, Wisconsin 54501
    United States

    Site Not Available

  • Marshfield Clinic - Indianhead Center

    Rice Lake, Wisconsin 54868
    United States

    Site Not Available

  • Marshfield Clinic at Saint Michael's Hospital

    Stevens Point, Wisconsin 54481
    United States

    Site Not Available

  • Marshfield Clinic - Wausau Center

    Wausau, Wisconsin 54401
    United States

    Site Not Available

  • Aurora Women's Pavilion of West Allis Memorial Hospital

    West Allis, Wisconsin 53227
    United States

    Site Not Available

  • Marshfield Clinic - Weston Center

    Weston, Wisconsin 54476
    United States

    Site Not Available

  • Marshfield Clinic - Wisconsin Rapids Center

    Wisconsin Rapids, Wisconsin 54494
    United States

    Site Not Available

  • Welch Cancer Center at Sheridan Memorial Hospital

    Sheridan, Wyoming 82801
    United States

    Site Not Available

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