Evaluation of the Efficacy of Endermologie in Treatment of Cellulite and Body Contouring

Inclusion Criteria:

1. Written Informed Consent;

2. Subjects agreeing to take part of all procedures of the study (including mechanicalmassage, photographs), after being fully informed on the objectives and nature of theinvestigations;

3. Female subjects between 25-45 years;

4. Subjects presenting with cellulite grades I-III on buttocks and thighs;

5. Medical history and physical examination which, based on the investigator’s opinion,do not prevent the patient from taking part in the study and use the device underinvestigation;

6. Female subjects of childbearing age should present a negative urine pregnancy test andshould be using an effective contraceptive method (3 months before the enrollementuntill the end of the study);

7. Body Mass Index (BMI = weight/height2) beetwen 20,0-25,0 and 25,0-29,9;

8. Availability of the subject throughout the duration of the study (90 days);

9. Availability of the subject in maintaining a stable weight during the study (variationless than 2 kg)

10. Subjects with sufficient schooling and awareness to enable them to cooperate to thedegree required by this protocol.

Exclusion Criteria:

1. Pregnant women or women intending to become pregnant during the study (next 3 months);

2. BMI superior 30,0;

3. Subjects with diabetes mellitus, cardiac insufficiency, asthma, or bronchitis;

4. Subjects participating in other clinical trials;

5. Subjects with neoplastic disorders, uncontrolled thyroid disorders or uncontrolledhypertension;

6. Subjects with coagulation disorders, using anticoagulants or tendency of bruises;

7. Subjects with vascular disorders (phlebitis or varicose veins) in the area to betreated;

8. Any prior aesthetic surgery affecting the area to be treated (liposuction,Subcision®), 3 months before the study, that may interfere with results;

9. Any other prior anti-cellulite treatment or body measures treatment, 30 days prior tothe study;

10. Subjects with inflammation or active infection in the area to be treated.

11. Subjects with a history of adverse effects, which in the investigator’s opinion shouldprevent the patient from participating in the study;

12. Patients with cutaneous or vascular alterations, that difficult visualization anddocumentation of cellulite;

13. Subjects with a history of medical treatment non-adherence or showing unwillingness toadhere to the study protocol;

14. Subjects who can not come to the visits (one missing visit/ month is allowed);

15. Subjects intending to initiate any intensive sport;

16. Subjects using analgesics, non-hormonal antiinflammatories, antihistaminics,corticosteroids, or diuretics;

17. Subjects tanned, or intending to expose the area of study to sun, artificial UV, orself-tanning during the study;

18. Any condition that, in the opinion of the investigator, can compromise the evaluationof the study.