A Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Last updated: December 5, 2007
Sponsor: Vertex Pharmaceuticals Incorporated
Overall Status: Completed

Phase

2

Condition

Arthritis And Arthritic Pain

Rheumatoid Arthritis

Musculoskeletal Diseases

Treatment

N/A

Clinical Study ID

NCT00395577
VX06-702-304
  • Ages 18-75
  • All Genders

Study Summary

The purpose of this study is to assess the safety and effects of VX-702 in subjects with moderate to severe rheumatoid arthritis and who are taking the drug methotrexate.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult patients 18 to 75 years of age with active RA

  • Must have been taking MTX for at least 6 months

  • No concurrent DMARD treatment (other than a stable dose of MTX)

Exclusion

Exclusion Criteria:

  • Planned major surgery (e.g., joint replacement) within the duration of the treatmentperiod of the study

  • Treated with intra-articular injections of corticosteroids within 28 days prior to Day 1

Study Design

Total Participants: 120
Study Start date:
November 01, 2006
Estimated Completion Date:
July 31, 2007

Connect with a study center

  • Call For Information

    Dimitrovgrad,
    Bulgaria

    Site Not Available

  • Call For Information

    Pleven,
    Bulgaria

    Site Not Available

  • Call For Information

    Sofia,
    Bulgaria

    Site Not Available

  • Call For Information

    Veliko Tarnovo,
    Bulgaria

    Site Not Available

  • Call For Information

    Osijek,
    Croatia

    Site Not Available

  • Call For Information

    Zagreb,
    Croatia

    Site Not Available

  • Call For Information

    Belgrade,
    Former Serbia and Montenegro

    Site Not Available

  • Call For Information

    Niska Banja,
    Former Serbia and Montenegro

    Site Not Available

  • Call For Information

    Zemun,
    Former Serbia and Montenegro

    Site Not Available

  • Call For Information

    Bytom,
    Poland

    Site Not Available

  • Call For Information

    Krakow,
    Poland

    Site Not Available

  • Call for Information

    Torun,
    Poland

    Site Not Available

  • Call For Information

    Zyrardow,
    Poland

    Site Not Available

  • Call For Information

    Novosibirsk,
    Russian Federation

    Site Not Available

  • Call For Information

    Saratov,
    Russian Federation

    Site Not Available

  • Call For Information

    St. Petersburg,
    Russian Federation

    Site Not Available

  • Call For Information

    Ljubljana,
    Slovenia

    Site Not Available

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