Nevirapine or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir in Human Immunodeficiency Virus (HIV)-1-infected Treatment Naive Adults

Inclusion criteria: Inclusion Criteria:

1. Signed informed consent in accordance with Good Clinical Practice (GCP) and localregulatory requirements prior to trial participation

2. HIV-1-infected males or females >= 18 years of age with positive serology confirmed byWestern blot

3. No previous antiretroviral treatment (of more than 7 days)

4. Males with CD4+ counts of < 400 cells/mm3 and females with CD4+ counts of < 250cells/mm3

5. NVP- and ATZ/r susceptibility based on HIV-1 genotypic resistance report

6. Adequate renal function defined as a calculated creatinine clearance (CLCr) >= 50ml/min according to the Cockcroft-Gault formula

7. Karnofsky score >= 70

8. Acceptable medical history, as assessed by the investigator

Exclusion criteria: Exclusion Criteria:

1. Active drug abuse or chronic alcoholism at the investigator's discretion

2. Hepatic cirrhosis stage Child-Pugh B or C

3. Female patients of child-bearing potential who:

• have a positive serum pregnancy test at screening or during the study,

• are breast feeding,

• are planning to become pregnant,

• are not willing to use a barrier method of contraception, or are not willing touse methods of contraception other than ethinyl estradiol containing oralcontraceptives

4. Laboratory parameters Division of Acquired Immunodeficiency Syndrome (DAIDS) > grade 2 (triglycerides > DAIDS grade 3; total cholesterol no restrictions)

5. Active hepatitis B or C disease, defined as HBsAg-positive or Hepatitis C-Virus-RiboNucleic Acid (HCV-RNA)- positive with Aspartate Transaminase/Alanine Transaminase (AST/ALT) > 2.5x Upper Limit of Normal (ULN) (DAIDS grade 1)

6. Hypersensitivity to any ingredients of the test products

7. Have therapy with nephrotoxic drugs (e.g., aminoglycosides, amphotericin B,vancomycin, cidofovir, foscarnet, cisplatin, pentamidine, tacrolimus, cyclosporine) orpotential competitors of renal excretion (e.g., cidofovir, acyclovir, valacyclovir,ganciclovir, valganciclovir, probenecid, high-dose non-steroidal anti-inflammatorydrugs (i.e., ibuprofen)) within 3 months prior to study screening or are expected toreceive these during the study

8. Patients who are receiving other concomitant treatments which are not permitted

9. Use of other investigational medications within 30 days before study entry or duringthe trial

10. Use of immunomodulatory drugs within 30 days before study entry or during the trial (e.g., interferon, cyclosporin, hydroxyurea, interleukin 2, chronic treatment withprednisone)

11. Patients with Progressive Multifocal Leukoencephalopathy (PML), Visceral Kaposi'sSarcoma (KS), and/or any lymphoma

12. Any AIDS defining illness that is unresolved, symptomatic or not stable on treatmentfor at least 12 weeks at screening visit

13. Patients who are receiving systemic treatment for malignant disease