Topical Vitamin B12 in Chronic Plaque Psoriasis

Last updated: July 6, 2006
Sponsor: Ruhr University of Bochum
Overall Status: Completed

Phase

3

Condition

Psoriasis And Psoriatic Disorders

Rosacea

Warts

Treatment

N/A

Clinical Study ID

NCT00350116
1-Stucker
  • Ages > 18
  • All Genders

Study Summary

Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of chronic plaque psoriasis.

Design: Multicenter, double-blind, randomized, placebo-controlled trial.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18years

  • chronic plaque psoriasis

Exclusion

Exclusion Criteria:

  • incapability of Vitamin B12

  • necessity of systemic therapy

  • use of other potentially psoriasis modifying drugs

Study Design

Total Participants: 48
Study Start date:
January 01, 2001
Estimated Completion Date:
December 31, 2004

Study Description

Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of chronic plaque psoriasis.

Design: Multicenter, double-blind, randomized, placebo-controlled trial. Setting: ambulatory patients in research or referral centers. Patients: Volunteer sample of 51 patients with chronic plaque psoriasis. Interventions: All Patients applied vitamin B12 cream twice daily for 8 weeks to one side of the body and placebo to the other.

Main outcome measures: Modified Psoriasis Area and Severity Index (PASI) at weeks 0, 2, 4, 6 and 8. Thickness and density of 3 references plaques determined by 20 MHz sonography. Assessment of efficiency and tolerability by patients and investigators.

Connect with a study center

  • Dep. Dermatology and Allergology, Ruhr-University Bochum

    Bochum, 44791
    Germany

    Site Not Available

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