Study of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido

Inclusion Criteria: Eligible women must:

1. Be 40-70 years old and in generally good health

2. Be post-menopausal with no spontaneous periods for 1 year

3. Be receiving a stable dose of hormone replacement therapy for at least 3 months priorto screening with the intention of maintaining that regimen.

4. Be, in her own judgment, in a stable, monogamous sexual relationship that is perceivedto be secure and communicative, for at least one year prior to study entry

5. Meet the criteria for having hypoactive sexual desire disorder

Exclusion Criteria: Eligible women must not:

1. Have received androgen therapy at any time during the past 3 months (during the past 7months if therapy was an investigational implantable product)

2. Be experiencing any chronic or acute life stress relating to any major life change

3. Be experiencing depression and/or receiving medication for such illness or disorder

4. Have current severe skin problems (such as severe or cystic acne) or allergy toadhesives (like the ones in bandages)

5. Have had a major illness, active gall bladder disease, or gynecological or breastsurgery within the last 6 months

6. Have a history of breast, endometrial, or other gynecological cancer at any timebefore study participation or other cancer within the last 5 years

7. Have diabetes, a history of cerebrovascular disease, thromboembolic disorders, heartattack, or angina at any time before study participation or thrombophlebitis withinthe last 5 years

8. Have abnormal laboratory test results upon initial screening for this study

9. Have previously participated in a clinical trial within 30 days or received aninvestigational medication within 30 days