Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery

Last updated: August 6, 2009
Sponsor: Bronovo Hospital
Overall Status: Completed

Phase

3

Condition

Osteoporosis

Dementia

Treatment

N/A

Clinical Study ID

NCT00250237
05-56
  • Ages > 75
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Hip fracture

  • 75 years and older

Exclusion

Exclusion Criteria:

  • Contra-indications for the use of haloperidol

  • Pre-operative delirium

  • Pre-operative use of haloperidol

Study Design

Total Participants: 220
Study Start date:
November 01, 2005
Estimated Completion Date:
February 28, 2009

Study Description

A post-operative delirium is a serious and frequent (35-65%) complication with high morbidity and mortality in high risk patients. In this study we investigate whether we can prevent a delirium from occuring after surgery in patients with a hip fracture of 75 years of age and older. It's a randomised double-blind single centre placebo-controlled study of haloperidol versus placebo.

Connect with a study center

  • Bronovo Hospital

    The Hague, Zuid Holland 2597 AX
    Netherlands

    Site Not Available

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