Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions

Inclusion Criteria:

1. Male or non-pregnant female patients minimum 18 years of age

2. Diagnosis of angina pectoris as defined by Canadian Cardiovascular SocietyClassification (CCS I, II, III, IV) OR unstable angina pectoris (BraunwaldClassification B&C, I-II) OR patients with documented silent ischemia;

3. Target lesions treatable with 4mm stent (visual estimate);

4. Target lesion is 30mm in length (visual estimate);

5. Target lesion stenosis is >50% and <100% (visual estimate);

Exclusion Criteria:

1. Patient has experienced a Q-wave or non-Q-wave myocardial infarction with documentedtotal CK >2 times normal within the preceding 24 hours and the CK and CK-MB enzymesremains above normal at the time of treatment;

2. Has unstable angina classified as Braunwald III B or C, or is having a periinfarction;

3. Documented Left ventricular ejection fraction 25%;

4. Impaired renal function (creatinine > 3.0 mg/dl) at the time of treatment;