STN-Stimulation Versus Best Medical Treatment in Advanced PD

Last updated: November 29, 2006
Sponsor: German Parkinson Study Group (GPS)
Overall Status: Completed

Phase

3

Condition

Parkinson's Disease

Dyskinesias

Treatment

N/A

Clinical Study ID

NCT00196911
A 125/00
Grant 01 GI 0201/01 GI 0401
  • Ages 20-75
  • All Genders

Study Summary

Assessment of the therapeutic effect of deep brain stimulation of the subthalamic nucleus compared with drug treatment alone in patients with advanced Parkinson's disease.

Eligibility Criteria

Inclusion

Inclusion Criteria: advanced Parkinson's disease with UPDRS III score >29/104 or Dyskinesia score > 2 or tremor >2

Exclusion

Exclusion Criteria: age>75 years depression psychosis surgical contraindications

Study Design

Total Participants: 156
Study Start date:
January 01, 2001
Estimated Completion Date:
January 31, 2005

Study Description

Patients are randomized either to medical treatment or subthalamic stimulation. The observation period was 6 months. The primary outcome criterium: PDQ-39 and UPDRS III.

Connect with a study center

  • Neurologische Klinik der Charité, Augustenburgerplatz 1

    Berlin, 13353
    Germany

    Site Not Available

  • Neurologische Klinik der Universität, Moorenstr. 5

    Düsseldorf, 40225
    Germany

    Site Not Available

  • Neurologische Klinik der Universität, Moorenstr. 5

    Düsseldorf, 40225
    Germany

    Site Not Available

  • Neurologische Klinik der Universität, Neuenheimerfeld 400

    Heidelberg, 69120
    Germany

    Site Not Available

  • Department of Neurology, Schittenhelmstr. 10

    Kiel, 24105
    Germany

    Site Not Available

  • Neurologische Klinik der Universität, Gleuelerstr. 50

    Köln, 50931
    Germany

    Site Not Available

  • Neurologische Klinik der Universität, Gleuelerstr. 50

    Köln, 50931
    Germany

    Site Not Available

  • Neurologische Klinik der Universität

    München, 81337
    Germany

    Site Not Available

  • Neurologische Klinik der Universität

    München, 81337
    Germany

    Site Not Available

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