Olmesartan Medoxomil in Hypertension and Renal Impairment

Inclusion Criteria:

• Mean sitting BP prior to randomization of 140-180/90-109 mmHg;

• Renal impairment prior to randomization of mild (50 ≤ CLcr ≥ 80 mL/min) to moderate (30 ≤ CLcr ≥50 mL/min) severity

Exclusion Criteria:

• Malignant hypertension or sitting BP greater than 180/109 mmHg;

• Severe heart failure, severe renal disease;

• Recent history of myocardial infarction, stroke or transient ischemic attack;

• History, clinical or current evidence of any significant gastrointestinal,respiratory, hematological, metabolic, immunological or any other underlying diseasewhich in the opinion of the investigator would interfere with the patient'sparticipation in the trial;

• Hypersensitivity or contraindications to ARBs or ACE inhibitors or any cross allergy;

• Treatment with dis-allowed medication;

• Pregnant or breastfeeding females or females of childbearing potential withoutadequate contraception;

• History of drug and/or alcohol abuse