Phase
Condition
Gynecological Infections
Urinary Incontinence
Urinary Tract Infections
Treatment
N/AClinical Study ID
Ages > 18 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Participant must report bladder pain/discomfort score of 3 or greater on a 0-10 Likertscale over the previous 4 weeks.
Participant must report a symptom score of abnormal urinary frequency of 3 or greateron a 0-10 Likert scale over the previous 4 weeks.
Symptoms of abnormal urinary frequency and bladder pain/discomfort must have beenpresent for at least six weeks prior to screening visit.
Exclusion
Exclusion Criteria:
Known allergy or intolerance to amitriptyline or any of its components.
Currently receives treatment with amitriptyline or other tricyclic antidepressant,selective serotonin reuptake inhibitor (SSRI) or serotonin and norepinephrine reuptakeinhibitor (SNRI), or monoamine oxidase (MAO) inhibitor antidepressants.
Previous treatment with amitriptyline or other tricyclics, hydroxyzine or otherantihistamines for bladder symptoms; pentosanpolysulfate; DMSO or any otherintravesical therapy, biofeedback or pelvic floor physical therapy for PBS symptoms
Study Design
Study Description
Connect with a study center
Queen's University
Kingston, Ontario K7L 2Y7
CanadaSite Not Available
Stanford University Medical Center
Stanford, California 94305
United StatesSite Not Available
Loyola University Medical Center
Maywood, Illinois 60153
United StatesSite Not Available
University of Iowa Hospitals and Clinic
Iowa City, Iowa 52242
United StatesSite Not Available
University of Maryland
Baltimore, Maryland 21201
United StatesSite Not Available
Henry Ford Hospital
Detroit, Michigan 48202
United StatesSite Not Available
William Beaumont Hospital
Royal Oak, Michigan 48073
United StatesSite Not Available
University of Rochester Medical Center
Rochester, New York 14642
United StatesSite Not Available
University of Pennsylvania
Philadelphia, Pennsylvania 19104
United StatesSite Not Available
University of Washington
Seattle, Washington 98195
United StatesSite Not Available
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