Seroquel in Bipolar Depression Versus SSRI

Inclusion Criteria:

• Male and female out-patients aged 18 to 65 years inclusive

• Diagnosis of Bipolar Disorder (Bipolar I or Bipolar II), most recent episode depressed

Exclusion Criteria:

• Current period of depression lasting less than 4 weeks or more than 12 months

• Use of prohibited medication

• Substance or alcohol dependence or abuse

• Current suicide risk or suicide attempt within 6 months

• Breast feeding or pregnancy

• Clinically relevant disease or clinical finding