SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD)

Last updated: December 10, 2009
Sponsor: Saegis Pharmaceuticals
Overall Status: Completed

Phase

2

Condition

Dementia

Memory Loss

Alzheimer's Disease

Treatment

N/A

Clinical Study ID

NCT00093951
IA0061
  • Ages 55-90
  • All Genders

Study Summary

The purpose of this trial is to determine the effect of a new drug, SGS742, on memory and cognition in patients with mild to moderate Alzheimer's disease.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 55 to 90 years of age

  • Diagnosed with mild to moderate Alzheimer's disease

  • Willing caregiver

  • In general good health

Exclusion

Exclusion Criteria:

  • Call 1-877-MY-MEMORY and ask to be referred to a study center located near you forentry criteria information. Prohibited Meds:

  • Alzheimer's medications (Aricept, Exelon, Remydl, Nemenda)

Study Design

Total Participants: 280
Study Start date:
April 01, 2004
Estimated Completion Date:
September 30, 2007

Study Description

SGS742 is a GABA(B) receptor antagonist. It is an orally active drug and possesses neurochemical and psychopharmacologic features that suggest it could improve memory and cognition in humans. The primary objective of the SGS742 clinical trial will be to determine the effect of SGS742 on memory and cognition in individuals diagnosed with mild to moderate Alzheimer's disease. The duration of the study is 3 months with 5 clinic visits.

Connect with a study center

  • Phoenix, Arizona 85013
    United States

    Site Not Available

  • Dedicated Clinical Research

    Sun City, Arizona 85351
    United States

    Site Not Available

  • Northwest NeuroSpecialists, PLLC

    Tucson, Arizona 85741
    United States

    Site Not Available

  • Clinical Trials Incorporated

    Little Rock, Arkansas 72205
    United States

    Site Not Available

  • Margolin Brain Institute

    Fresno, California 93720
    United States

    Site Not Available

  • NervePro Research

    Irvine, California 92618
    United States

    Site Not Available

  • Center for Neurologic Studies

    La Jolla, California 92037
    United States

    Site Not Available

  • Neuro Therapeutics, Inc.

    Pasadena, California 91105
    United States

    Site Not Available

  • Affiliated Research Institute

    San Diego, California 92108
    United States

    Site Not Available

  • Pacific Research Network, Inc.

    San Diego, California 92103
    United States

    Site Not Available

  • San Francisco Clinical Research Center

    San Francisco, California 94109
    United States

    Site Not Available

  • Southern California Clinical Research, Inc.

    San Marino, California 91108
    United States

    Site Not Available

  • The Mile High Research Center

    Denver, Colorado 80218
    United States

    Site Not Available

  • Research Center for Clinical Studies, Inc.

    Darien, Connecticut 06820
    United States

    Site Not Available

  • Stamford, Connecticut 06902
    United States

    Site Not Available

  • Baumel-Eisner Neuromedical Institute, Inc.

    Boca Raton, Florida 33486
    United States

    Site Not Available

  • Bradenton Neurology, Inc.

    Bradenton, Florida 34205
    United States

    Site Not Available

  • Brain Matters, Inc.

    Delray Beach, Florida 33445
    United States

    Site Not Available

  • Baumel-Eisner Neuromedical Institute

    Ft. Lauderdale, Florida 33321
    United States

    Site Not Available

  • Berma Research Group

    Hialeah, Florida 33016
    United States

    Site Not Available

  • Allied Clinical Trials, The Neurology Group

    Miami, Florida 33125
    United States

    Site Not Available

  • Tukoi Institute for Clinical Research

    Miami, Florida 33161
    United States

    Site Not Available

  • Baumel-Eisner Neuromedical Institute

    Miami Beach, Florida 33154
    United States

    Site Not Available

  • Ocala Neurodiagnostic Center

    Ocala, Florida 34471
    United States

    Site Not Available

  • Orange City, Florida 32763
    United States

    Site Not Available

  • Palm Springs, Florida 33461
    United States

    Site Not Available

  • Pompano Beach, Florida 33064
    United States

    Site Not Available

  • Tampa, Florida 33647
    United States

    Site Not Available

  • CSI Research

    Decatur, Georgia 30030
    United States

    Site Not Available

  • DeKalb Neurology Associates, LLC

    Decatur, Georgia 30033
    United States

    Site Not Available

  • MidAmerica Neuroscience Institute

    Lenexa, Kansas 66214
    United States

    Site Not Available

  • Neurology Department, LSU Health Sciences Center

    Shreveport, Louisiana 71103
    United States

    Site Not Available

  • Baystate Medical Center

    Springfield, Massachusetts 01199
    United States

    Site Not Available

  • SW Medical Associates

    Las Vegas, Nevada 89102
    United States

    Site Not Available

  • Manchester, New Jersey 08759
    United States

    Site Not Available

  • Psychopharmacology Research Association of Princeton, P.C.

    Princeton, New Jersey 08540
    United States

    Site Not Available

  • United Health Services Office of Clinical Trials

    Johnson City, New York 13790
    United States

    Site Not Available

  • New York, New York 10021
    United States

    Site Not Available

  • Raleigh Neurology

    Raleigh, North Carolina 27607
    United States

    Site Not Available

  • Raleigh, North Carolina 27609
    United States

    Site Not Available

  • Winston-Salem, North Carolina 27103
    United States

    Site Not Available

  • MetroHealth Medical Center

    Cleveland, Ohio 44109
    United States

    Site Not Available

  • University Memory and Aging Center

    Cleveland, Ohio 44120
    United States

    Site Not Available

  • Toledo, Ohio 43623
    United States

    Site Not Available

  • Lynn Health Science Institute

    Oklahoma City, Oklahoma 73112
    United States

    Site Not Available

  • Oregon Center for Clinical Investigations, Inc.

    Eugene, Oregon 97401
    United States

    Site Not Available

  • Medford, Oregon 97504
    United States

    Site Not Available

  • Bala Cynwyd, Pennsylvania 19004
    United States

    Site Not Available

  • The Clinical Trial Center, LLC

    Jenkintown, Pennsylvania 19046
    United States

    Site Not Available

  • RI Mood & Memory Research Institute

    E Providence, Rhode Island 02914
    United States

    Site Not Available

  • Madison, Tennessee 37115
    United States

    Site Not Available

  • Senior Adults Specialty Research, Inc.

    Austin, Texas 78757
    United States

    Site Not Available

  • Claghorn-Lesem Research Clinic, Ltd.

    Bellaire, Texas 77401
    United States

    Site Not Available

  • Radiant Research San Antonio

    San Antonio, Texas 78229
    United States

    Site Not Available

  • Texas Medical Research Associates, LLC

    San Antonio, Texas 78238
    United States

    Site Not Available

  • Grayline Clinical Drug Trials

    Wichita Falls, Texas 76309
    United States

    Site Not Available

  • Bennington, Vermont 05201
    United States

    Site Not Available

  • National Clinical Research, Inc.

    Richmond, Virginia 23294
    United States

    Site Not Available

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