Phase
Condition
Anxiety Disorders
Panic Disorders
Mood Disorders
Treatment
N/AClinical Study ID
Ages 18-65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM-IV)criteria for generalized social phobia
Willing and able to give written informed consent
English-speaking
Exclusion
Exclusion Criteria:
Prior or current diagnosis of schizophrenia, schizoaffective disorder, organic mentaldisorder, bipolar disorder, or antisocial, schizotypal, and schizoid personalitydisorders
Suicidal thoughts
History of failed paroxetine treatment of at least 6 weeks' duration at adequate dosesor a history of failed outcome of a previous adequate trial of CBT
Clinically significant and/or unstable medical disease
Pregnancy or breast-feeding. Women of childbearing potential will be required to signa statement indicating their intention to avoid pregnancy during the study through theuse of an effective method of contraception.
Alcohol or substance abuse or dependence within the past 3 months. Patients with apositive drug screen but no substance abuse disorder will be eligible for the study,provided they have not met criteria for abuse/dependence within the last 6 months andprovide two clean urine samples 2 weeks apart.
Current or past history of seizure disorder (except febrile seizure in childhood)
Conditions that contraindicate the use of paroxetine
Inability to tolerate or unwillingness to accept a drug-free period of 4 weeks formonoamine oxidase inhibitors (MAOIs) or fluoxetine and 2 weeks for other selectiveserotonin reuptake inhibitors (SSRIs), neuroleptics, antidepressants, benzodiazepines,mood stabilizers, buspirone, beta-adrenergic blockers, or other psychotropic drugsprior to beginning the study
Currently receiving psychotherapy
Study Design
Study Description
Connect with a study center
New York State Psychiatric Institute Anxiety Disorders Clinic
New York, New York 10032
United StatesSite Not Available
Adult Anxiety Clinic of Temple University
Philadelphia, Pennsylvania 19122-6085
United StatesSite Not Available
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