Phase
Condition
Genitourinary Cancer
Vulvar Dysplasia And Carcinoma
Vaginal Cancer
Treatment
N/AClinical Study ID
Female
Study Summary
Eligibility Criteria
Inclusion
DISEASE CHARACTERISTICS:
Histologically confirmed stage I, II, III, or IVA squamous cell carcinoma of the vulva amenable to curative treatment with surgery, radiotherapy, or both
At least 1 positive inguinal and/or femoral lymph node
No inoperable (fixed or ulcerating) groin nodes
Must not require resection of urethra or anal sphincter to achieve negative margins
Must have undergone vulvar biopsy and bilateral inguinal/femoral lymph node dissection within 8 weeks of randomization
No metastatic disease
PATIENT CHARACTERISTICS:
Age:
- Any age
Performance status:
- GOG 0-2
Life expectancy:
- Not specified
Hematopoietic:
WBC at least 3,000/mm^3
Platelet count at least 100,000/mm^3
Granulocyte count at least 1,500/mm^3
Hepatic:
Bilirubin no greater than 1.5 times normal
SGOT no greater than 3 times normal
Alkaline phosphatase no greater than 3 times normal
Renal:
- Creatinine no greater than 2.0 mg/dL
Other:
Not pregnant or nursing
Fertile patients must use effective contraception
No other prior invasive malignancy within the past 5 years except nonmelanoma skin cancer
PRIOR CONCURRENT THERAPY:
Biologic therapy:
- Not specified
Chemotherapy:
- No prior chemotherapy
Endocrine therapy:
- Not specified
Radiotherapy:
See Disease Characteristics
No prior radiotherapy
Surgery:
See Disease Characteristics
No more than 8 weeks since prior surgery
Other:
- No prior therapy for another malignancy that would preclude study
Study Design
Study Description
Connect with a study center
Tom Baker Cancer Center - Calgary
Calgary, Alberta T2N 4N2
CanadaSite Not Available
Toronto Sunnybrook Regional Cancer Centre
Toronto, Ontario M4N 3M5
CanadaSite Not Available
Community Hospital of Los Gatos
Los Gatos, California 95032
United StatesSite Not Available
Chao Family Comprehensive Cancer Center
Orange, California 92868
United StatesSite Not Available
University of Colorado Cancer Center
Denver, Colorado 80010
United StatesSite Not Available
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida 33612-9497
United StatesSite Not Available
Indiana University Cancer Center
Indianapolis, Indiana 46202-5289
United StatesSite Not Available
Holden Comprehensive Cancer Center at The University of Iowa
Iowa City, Iowa 52242-1009
United StatesSite Not Available
Tufts University School of Medicine
Boston, Massachusetts 02111
United StatesSite Not Available
Mayo Clinic Cancer Center
Rochester, Minnesota 55905
United StatesSite Not Available
University of Mississippi Medical Center
Jackson, Mississippi 39216-4505
United StatesSite Not Available
Ellis Fischel Cancer Center - Columbia
Columbia, Missouri 65203
United StatesSite Not Available
Mallinckrodt Institute of Radiology
Saint Louis, Missouri 63108
United StatesSite Not Available
Cancer Center of Albany Medical Center
Albany, New York 12208
United StatesSite Not Available
Schneider Children's Hospital at North Shore
Manhasset, New York 11030
United StatesSite Not Available
Lineberger Comprehensive Cancer Center, UNC
Chapel Hill, North Carolina 27599-7295
United StatesSite Not Available
Duke Comprehensive Cancer Center
Durham, North Carolina 27710
United StatesSite Not Available
Comprehensive Cancer Center at Wake Forest University
Winston-Salem, North Carolina 27157-1082
United StatesSite Not Available
Barrett Cancer Center, The University Hospital
Cincinnati, Ohio 45267-0502
United StatesSite Not Available
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United StatesSite Not Available
Ireland Cancer Center
Cleveland, Ohio 44106-5065
United StatesSite Not Available
Arthur G. James Cancer Hospital - Ohio State University
Columbus, Ohio 43210-1240
United StatesSite Not Available
University of Oklahoma College of Medicine
Oklahoma City, Oklahoma 73190
United StatesSite Not Available
Abington Memorial Hospital
Abington, Pennsylvania 19001
United StatesSite Not Available
Milton S. Hershey Medical Center
Hershey, Pennsylvania 17033-0850
United StatesSite Not Available
Brookview Research, Inc.
Nashville, Tennessee 37203
United StatesSite Not Available
Simmons Cancer Center - Dallas
Dallas, Texas 75235-9154
United StatesSite Not Available
M.D. Anderson CCOP Research Base
Houston, Texas 77030-4009
United StatesSite Not Available
Fletcher Allen Health Care - Medical Center Campus
Burlington, Vermont 05401
United StatesSite Not Available
Tacoma General Hospital
Tacoma, Washington 98405
United StatesSite Not Available

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