Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy

Last updated: October 15, 2020
Sponsor: Radiation Therapy Oncology Group
Overall Status: Completed

Phase

3

Condition

Inflammatory Bowel Disease

Stomach Discomfort

Infectious Colitis

Treatment

N/A

Clinical Study ID

NCT00003825
RTOG-9809
CDR0000066979
  • Ages < 120
  • All Genders

Study Summary

RATIONALE: Pentosan polysulfate may be effective in treating side effects of radiation therapy to the abdomen or pelvis. It is not yet known whether pentosan polysulfate is more effective than no further therapy for treating gastrointestinal disturbance caused by previous radiation therapy.

PURPOSE: Randomized phase III trial to determine the effectiveness of pentosan polysulfate in treating patients who have inflammation of the rectum, diarrhea, or blood in stools caused by previous radiation therapy to the abdomen and pelvis.

Eligibility Criteria

Inclusion

DISEASE CHARACTERISTICS: Must have received prior radiotherapy to the abdomen and pelvis and now have radiation related gastrointestinal symptoms (which were not present before the radiotherapy and/or attributed to other causes) Proctitis Diarrhea Melena (blood in stools) Severity of symptoms classified as grade 1, 2, or 3

PATIENT CHARACTERISTICS: Age: Any age Performance status: Not specified Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: No bleeding ulcers No bleeding diathesis

PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: At least 1 month since prior chemotherapy No concurrent chemotherapy Endocrine therapy: Concurrent hormonal therapy for prostate cancer allowed Radiotherapy: See Disease Characteristics At least 4 weeks since prior radiotherapy Surgery: No prior bowel resection At least 3 weeks since prior surgery Other: No concurrent anticoagulation therapy (except aspirin)

Study Design

Total Participants: 174
Study Start date:
June 01, 1999
Estimated Completion Date:

Study Description

OBJECTIVES: I. Evaluate the efficacy of pentosan polysulfate in patients with gastrointestinal tract sequelae after radiotherapy to the abdomen and pelvis. II. Determine the toxic effects of this drug in these patients. III. Determine the effect of this drug on symptoms and quality of life of these patients.

OUTLINE: This is a randomized study. Patients are randomized to 1 of 2 treatment arms. Arm I: Patients receive oral pentosan polysulfate three times a day for 2-6 months. Arm II: Patients receive oral placebo three times a day for 2-6 months. Both arms: Patients may receive retreatment for two months if symptoms return and last for at least 2 weeks. Quality of life is assessed before treatment, and at each follow up visit. Patients are followed every 2 months for 6 months, then every 3 months for 18 months, then annually for 3 years.

PROJECTED ACCRUAL: A total of 174 patients will be accrued for this study within 3 years.

Connect with a study center

  • Tom Baker Cancer Center - Calgary

    Calgary, Alberta T2N 4N2
    Canada

    Site Not Available

  • Cross Cancer Institute

    Edmonton, Alberta T6G 1Z2
    Canada

    Site Not Available

  • BC Cancer Agency

    Vancouver, British Columbia V5Z 4E6
    Canada

    Site Not Available

  • Doctor Leon Richard Oncology Centre

    Moncton, New Brunswick E1C 8X3
    Canada

    Site Not Available

  • Saint John Regional Hospital

    Saint John, New Brunswick E2L 4L2
    Canada

    Site Not Available

  • Dr. H. Bliss Murphy Cancer Centre

    St. Johns, Newfoundland and Labrador A1B 3V6
    Canada

    Site Not Available

  • Nova Scotia Cancer Centre

    Halifax, Nova Scotia B3H 1V7
    Canada

    Site Not Available

  • Cancer Care Ontario-Hamilton Regional Cancer Centre

    Hamilton, Ontario L8V 5C2
    Canada

    Site Not Available

  • Kingston Regional Cancer Centre

    Kingston, Ontario K7L 5P9
    Canada

    Site Not Available

  • Cancer Care Ontario-London Regional Cancer Centre

    London, Ontario N6A 4L6
    Canada

    Site Not Available

  • Ottawa Regional Cancer Centre - General Campus

    Ottawa, Ontario K1H 1C4
    Canada

    Site Not Available

  • Northeastern Ontario Regional Cancer Centre, Sudbury

    Sudbury, Ontario P3E 5J1
    Canada

    Site Not Available

  • Northwestern Ontario Regional Cancer Centre, Thunder Bay

    Thunder Bay, Ontario P7A 7T1
    Canada

    Site Not Available

  • Princess Margaret Hospital

    Toronto, Ontario M5G 2M9
    Canada

    Site Not Available

  • Toronto Sunnybrook Regional Cancer Centre

    Toronto, Ontario M4N 3M5
    Canada

    Site Not Available

  • Centre Universitaire de Sante de l'Estrie - Site Fleurimont

    Fleurimont, Quebec J1H 5N4
    Canada

    Site Not Available

  • Centre Hospitalier de l'Universite de Montreal

    Montreal, Quebec H2L-4M1
    Canada

    Site Not Available

  • McGill University Department of Oncology

    Montreal, Quebec H2W 1S6
    Canada

    Site Not Available

  • Saskatoon Cancer Centre

    Saskatoon, Saskatchewan S7N 4H4
    Canada

    Site Not Available

  • University of Alabama Comprehensive Cancer Center

    Birmingham, Alabama 35294
    United States

    Site Not Available

  • Comprehensive Cancer Institute of Huntsville

    Huntsville, Alabama 35801
    United States

    Site Not Available

  • Huntsville Hospital System

    Huntsville, Alabama 35801
    United States

    Site Not Available

  • MBCCOP - University of South Alabama

    Mobile, Alabama 36688
    United States

    Site Not Available

  • Mobile Infirmary Medical Center

    Mobile, Alabama 36640-0460
    United States

    Site Not Available

  • Urology Associates - Mobile AL

    Mobile, Alabama 36640
    United States

    Site Not Available

  • Alabama Oncology, LLC

    Montgomery, Alabama 36106-2801
    United States

    Site Not Available

  • Radiation Oncology Associates of West Alabama

    Tuscallosa, Alabama 35401
    United States

    Site Not Available

  • Radiation Oncology Associates of West Alabama

    Tuscaloosa, Alabama 35401
    United States

    Site Not Available

  • Providence Cancer Therapy Center

    Anchorage, Alaska 99508
    United States

    Site Not Available

  • Arizona Cancer Center

    Tucson, Arizona 85724
    United States

    Site Not Available

  • Mount Diablo Medical Center

    Concord, California 94524-4110
    United States

    Site Not Available

  • California Cancer Center

    Fresno, California 93720
    United States

    Site Not Available

  • Saint Agnes Cancer Center

    Fresno, California 93720
    United States

    Site Not Available

  • Glendale Memorial Hospital and Health Center

    Glendale, California 91204
    United States

    Site Not Available

  • Sutter Health Western Division Cancer Research Group

    Greenbrae, California 94904
    United States

    Site Not Available

  • University of California San Diego Cancer Center

    La Jolla, California 92093-0658
    United States

    Site Not Available

  • Loma Linda University Medical Center

    Loma Linda, California 92354
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Long Beach

    Long Beach, California 90822
    United States

    Site Not Available

  • Beckman Research Institute, City of Hope

    Los Angeles, California 91010
    United States

    Site Not Available

  • Jonsson Comprehensive Cancer Center, UCLA

    Los Angeles, California 90095-1781
    United States

    Site Not Available

  • Kaiser Permanente Medical Center - Los Angeles

    Los Angeles, California 90027
    United States

    Site Not Available

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California 90033-0800
    United States

    Site Not Available

  • CCOP - Bay Area Tumor Institute

    Oakland, California 94609-3305
    United States

    Site Not Available

  • Cancer Care Center

    Pomona, California 91767
    United States

    Site Not Available

  • Radiation Oncology Center - Sacramento

    Sacramento, California 95816
    United States

    Site Not Available

  • Radiation Medical Group, Inc.

    San Diego, California 92101-1492
    United States

    Site Not Available

  • UCSF Cancer Center and Cancer Research Institute

    San Francisco, California 94115-0128
    United States

    Site Not Available

  • O'Connor Hospital

    San Jose, California 95128
    United States

    Site Not Available

  • CCOP - Santa Rosa Memorial Hospital

    Santa Rosa, California 95403
    United States

    Site Not Available

  • Stanford University

    Stanford, California 94305
    United States

    Site Not Available

  • Memorial Hospital Cancer Center

    Colorado Springs, Colorado 80909
    United States

    Site Not Available

  • University of Colorado Cancer Center

    Denver, Colorado 80262
    United States

    Site Not Available

  • Bridgeport Hospital

    Bridgeport, Connecticut 06610
    United States

    Site Not Available

  • Whittingham Cancer Center

    Norwalk, Connecticut 06856
    United States

    Site Not Available

  • CCOP - Christiana Care Health Services

    Wilmington, Delaware 19899
    United States

    Site Not Available

  • Walter Reed Army Medical Center

    Washington, District of Columbia 20307-5000
    United States

    Site Not Available

  • Lykes Center for Radiation Therapy

    Clearwater, Florida 33757-0210
    United States

    Site Not Available

  • Halifax Medical Center

    Daytona Beach, Florida 32114
    United States

    Site Not Available

  • Radiation Therapy Associates - Fort Myers

    Fort Myers, Florida 33901
    United States

    Site Not Available

  • University of Florida Health Science Center

    Gainesville, Florida 32610-0296
    United States

    Site Not Available

  • Health First Holmes Regional Medical Center

    Melbourne, Florida 32901
    United States

    Site Not Available

  • Baptist Hospital of Miami

    Miami, Florida 33176-2197
    United States

    Site Not Available

  • Sylvester Cancer Center, University of Miami

    Miami, Florida 33136
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Miami

    Miami, Florida 33125
    United States

    Site Not Available

  • CCOP - Mount Sinai Medical Center

    Miami Beach, Florida 33140
    United States

    Site Not Available

  • Florida Radiation Oncology Group

    Orange Park, Florida 32073
    United States

    Site Not Available

  • MD Anderson Cancer Center Orlando

    Orlando, Florida 32806
    United States

    Site Not Available

  • Bay Medical Center

    Panama City, Florida 32401
    United States

    Site Not Available

  • Gulf Coast Cancer Treatment Center

    Panama City, Florida 32405-4587
    United States

    Site Not Available

  • West Florida Cancer Institute - Pensacola

    Pensacola, Florida 32514
    United States

    Site Not Available

  • Bayfront Medical Center

    Saint Petersburg, Florida 33701
    United States

    Site Not Available

  • Sarasota Radiation and Medical Oncology Center

    Sarasota, Florida 34233
    United States

    Site Not Available

  • Tallahassee Memorial Healthcare

    Tallahassee, Florida 32308
    United States

    Site Not Available

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida 33612
    United States

    Site Not Available

  • CCOP - Atlanta Regional

    Atlanta, Georgia 30342-1701
    United States

    Site Not Available

  • Emory University Hospital - Atlanta

    Atlanta, Georgia 30322
    United States

    Site Not Available

  • Medical Center/John B. Amos Community Cancer Center

    Columbus, Georgia 31902
    United States

    Site Not Available

  • InterCommunity Cancer Center at Rome

    Rome, Georgia 30161
    United States

    Site Not Available

  • Northwest Community Hospital

    Arlington Heights, Illinois 60005
    United States

    Site Not Available

  • Northwestern Memorial Hospital

    Chicago, Illinois 60611
    United States

    Site Not Available

  • University of Chicago Cancer Research Center

    Chicago, Illinois 60637
    United States

    Site Not Available

  • CCOP - Central Illinois

    Decatur, Illinois 62526
    United States

    Site Not Available

  • Provena St. Joseph Hospital- Regional Cancer Care Center

    Elgin, Illinois 60123
    United States

    Site Not Available

  • Ingalls Memorial Hospital

    Harvey, Illinois 60426
    United States

    Site Not Available

  • Loyola University Medical Center

    Maywood, Illinois 60153
    United States

    Site Not Available

  • Lutheran General Cancer Care Center

    Park Ridge, Illinois 60068
    United States

    Site Not Available

  • Methodist Medical Center of Illinois

    Peoria, Illinois 61636
    United States

    Site Not Available

  • St. John's Medical Center

    Anderson, Indiana 46016
    United States

    Site Not Available

  • Clarion Health Partners Inc.

    Indianapolis, Indiana 46206-1367
    United States

    Site Not Available

  • Community Hospitals of Indianapolis - Regional Cancer Center

    Indianapolis, Indiana 46219
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Indianapolis (Roudebush)

    Indianapolis, Indiana 46202
    United States

    Site Not Available

  • Ball Memorial Hospital

    Muncie, Indiana 47303-3499
    United States

    Site Not Available

  • Memorial Hospital of South Bend

    South Bend, Indiana 46601
    United States

    Site Not Available

  • St. Joseph's Radiation Oncology Center

    South Bend, Indiana 46617
    United States

    Site Not Available

  • Wendt Regional Cancer Center of Finley Hospital

    Dubuque, Iowa 52001
    United States

    Site Not Available

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa 52242
    United States

    Site Not Available

  • Albert B. Chandler Medical Center, University of Kentucky

    Lexington, Kentucky 40536-0084
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Lexington

    Lexington, Kentucky 40511-1093
    United States

    Site Not Available

  • James Graham Brown Cancer Center

    Louisville, Kentucky 40202
    United States

    Site Not Available

  • Louisville Radiation Oncology

    Louisville, Kentucky 40215
    United States

    Site Not Available

  • Merle M. Mahr Cancer Center

    Madisonville, Kentucky 42431
    United States

    Site Not Available

  • Western Baptist Hospital

    Paducah, Kentucky 42001
    United States

    Site Not Available

  • Mary Bird Perkins Cancer Center

    Baton Rouge, Louisiana 70809
    United States

    Site Not Available

  • Romagosa Radiation Oncology Center

    Lafayette, Louisiana 70501
    United States

    Site Not Available

  • CCOP - Ochsner

    New Orleans, Louisiana 70121
    United States

    Site Not Available

  • MBCCOP - LSU Medical Center

    New Orleans, Louisiana 70112
    United States

    Site Not Available

  • Tulane University School of Medicine

    New Orleans, Louisiana 70112
    United States

    Site Not Available

  • Maine Medical Center

    Portland, Maine 04102
    United States

    Site Not Available

  • Anne Arundel Oncology Center

    Annapolis, Maryland 21401
    United States

    Site Not Available

  • Greater Baltimore Medical Center and Cancer Center

    Baltimore, Maryland 21204
    United States

    Site Not Available

  • Harbor Hospital Center

    Baltimore, Maryland 21225
    United States

    Site Not Available

  • Johns Hopkins Oncology Center

    Baltimore, Maryland 21231
    United States

    Site Not Available

  • Radiation Oncology Affiliates of Maryland, P.A.

    Baltimore, Maryland 21237
    United States

    Site Not Available

  • Sinai Hospital of Baltimore

    Baltimore, Maryland 21225
    United States

    Site Not Available

  • Peninsula Regional Medical Center

    Salisbury, Maryland 21801
    United States

    Site Not Available

  • Cape Cod Hospital

    Hyannis, Massachusetts 02601
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Boston (Jamaica Plain)

    Jamaica Plain, Massachusetts 02130
    United States

    Site Not Available

  • CCOP - Ann Arbor Regional

    Ann Arbor, Michigan 48106
    United States

    Site Not Available

  • Saint Josephs Mercy Hospital

    Ann Arbor, Michigan 48106
    United States

    Site Not Available

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan 48109-0752
    United States

    Site Not Available

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan 48201
    United States

    Site Not Available

  • Henry Ford Hospital

    Detroit, Michigan 48202
    United States

    Site Not Available

  • Hurley Medical Center

    Flint, Michigan 48503
    United States

    Site Not Available

  • McLaren Regional Cancer Center

    Flint, Michigan 48432
    United States

    Site Not Available

  • CCOP - Kalamazoo

    Kalamazoo, Michigan 49007-3731
    United States

    Site Not Available

  • Sparrow Regional Cancer Center

    Lansing, Michigan 48909
    United States

    Site Not Available

  • Marquette General Hospital

    Marquette, Michigan 49855
    United States

    Site Not Available

  • MidMichigan Regional Medical Center

    Midland, Michigan 48670
    United States

    Site Not Available

  • William Beaumont Hospital

    Royal Oak, Michigan 48073
    United States

    Site Not Available

  • St. Mary's Medical Center

    Saginaw, Michigan 48601
    United States

    Site Not Available

  • Mayo Clinic Cancer Center

    Rochester, Minnesota 55905
    United States

    Site Not Available

  • CCOP - Metro-Minnesota

    Saint Louis Park, Minnesota 55416
    United States

    Site Not Available

  • North Mississippi Medical Center/Cancer Center

    Tupelo, Mississippi 38801
    United States

    Site Not Available

  • Ellis Fischel Cancer Center - Columbia

    Columbia, Missouri 65203
    United States

    Site Not Available

  • CCOP - Kansas City

    Kansas City, Missouri 64131
    United States

    Site Not Available

  • Mallinckrodt Institute of Radiology

    Saint Louis, Missouri 63110
    United States

    Site Not Available

  • St. Louis University Health Sciences Center

    Saint Louis, Missouri 63110-0250
    United States

    Site Not Available

  • CCOP - Cancer Research for the Ozarks

    Springfield, Missouri 65807
    United States

    Site Not Available

  • Cancer Research for the Ozarks

    Springfield, Missouri 65807
    United States

    Site Not Available

  • CCOP - Montana Cancer Consortium

    Billings, Montana 59101
    United States

    Site Not Available

  • Methodist Cancer Center - Omaha

    Omaha, Nebraska 68114
    United States

    Site Not Available

  • Nebraska Health System

    Omaha, Nebraska 68198-7400
    United States

    Site Not Available

  • CCOP - Southern Nevada Cancer Research Foundation

    Las Vegas, Nevada 89106
    United States

    Site Not Available

  • Norris Cotton Cancer Center

    Lebanon, New Hampshire 03756
    United States

    Site Not Available

  • Elliot Regional Cancer Center

    Manchester, New Hampshire 03103
    United States

    Site Not Available

  • Veterans Affairs Medical Center - East Orange

    East Orange, New Jersey 07018-1095
    United States

    Site Not Available

  • John F. Kennedy Medical Center

    Edison, New Jersey 08818
    United States

    Site Not Available

  • Trinitas Hospital - Jersey Street Campus

    Elizabeth, New Jersey 07201
    United States

    Site Not Available

  • Monmouth Medical Center

    Long Branch, New Jersey 07740
    United States

    Site Not Available

  • South Jersey Hospital - Millville

    Millville, New Jersey 08332
    United States

    Site Not Available

  • Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County

    Mount Holly, New Jersey 08060
    United States

    Site Not Available

  • Cancer Institute of New Jersey

    New Brunswick, New Jersey 08901
    United States

    Site Not Available

  • Newark Beth Israel Medical Center

    Newark, New Jersey 07112
    United States

    Site Not Available

  • Atlantic City Medical Center

    Pomona, New Jersey 08240
    United States

    Site Not Available

  • Community Medical Center

    Toms River, New Jersey 08755
    United States

    Site Not Available

  • St. Francis Medical Center

    Trenton, New Jersey 08629
    United States

    Site Not Available

  • Associated Radiologists, P.A.

    Warren, New Jersey 07059
    United States

    Site Not Available

  • Saint Joseph Medical Center

    Albuquerque, New Mexico 87102
    United States

    Site Not Available

  • Cancer Center of Albany Medical Center

    Albany, New York 12208
    United States

    Site Not Available

  • Albert Einstein Comprehensive Cancer Center

    Bronx, New York 10461
    United States

    Site Not Available

  • New York Methodist Hospital

    Brooklyn, New York 11215-3609
    United States

    Site Not Available

  • State University of New York Health Science Center at Brooklyn

    Brooklyn, New York 11203
    United States

    Site Not Available

  • Roswell Park Cancer Institute

    Buffalo, New York 14263-0001
    United States

    Site Not Available

  • Finger Lakes Radiation Oncology, P.C.

    Clifton Springs, New York 14432
    United States

    Site Not Available

  • CCOP - North Shore University Hospital

    Manhasset, New York 11030
    United States

    Site Not Available

  • Beth Israel Medical Center

    New York, New York 10003
    United States

    Site Not Available

  • Herbert Irving Comprehensive Cancer Center

    New York, New York 10032
    United States

    Site Not Available

  • Memorial Sloan-Kettering Cancer Center

    New York, New York 10021
    United States

    Site Not Available

  • NYU School of Medicine's Kaplan Comprehensive Cancer Center

    New York, New York 10016
    United States

    Site Not Available

  • Champlain Valley Physicians Hospital Medical Center

    Plattsburgh, New York 12901
    United States

    Site Not Available

  • Vassar Brothers Hospital

    Poughkeepsie, New York 12601
    United States

    Site Not Available

  • University of Rochester Cancer Center

    Rochester, New York 14642
    United States

    Site Not Available

  • New York Medical College

    Valhalla, New York 10595
    United States

    Site Not Available

  • Lineberger Comprehensive Cancer Center, UNC

    Chapel Hill, North Carolina 27599-7295
    United States

    Site Not Available

  • Northeast Medical Center

    Concord, North Carolina 28025
    United States

    Site Not Available

  • East Carolina University School of Medicine

    Greenville, North Carolina 27858-4354
    United States

    Site Not Available

  • Catawba Memorial Hospital

    Hickory, North Carolina 28601
    United States

    Site Not Available

  • CCOP - Southeast Cancer Control Consortium

    Winston-Salem, North Carolina 27104-4241
    United States

    Site Not Available

  • Comprehensive Cancer Center of Wake Forest University Baptist Medical Center

    Winston-Salem, North Carolina 27157-1082
    United States

    Site Not Available

  • Meritcare Roger Maris Cancer Center

    Fargo, North Dakota 58122
    United States

    Site Not Available

  • UNIMED Medical Center

    Minot, North Dakota 58701
    United States

    Site Not Available

  • Akron City Hospital

    Akron, Ohio 44309
    United States

    Site Not Available

  • Akron General Medical Center

    Akron, Ohio 44302
    United States

    Site Not Available

  • Christ Hospital

    Cincinnati, Ohio 45219
    United States

    Site Not Available

  • Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio 44195
    United States

    Site Not Available

  • Ireland Cancer Center

    Cleveland, Ohio 44106-5065
    United States

    Site Not Available

  • University Hospitals of Cleveland

    Cleveland, Ohio 44106
    United States

    Site Not Available

  • Arthur G. James Cancer Hospital - Ohio State University

    Columbus, Ohio 43210
    United States

    Site Not Available

  • CCOP - Columbus

    Columbus, Ohio 43206
    United States

    Site Not Available

  • CCOP - Dayton

    Kettering, Ohio 45429
    United States

    Site Not Available

  • CCOP - Toledo Community Hospital Oncology Program

    Toledo, Ohio 43623-3456
    United States

    Site Not Available

  • St. Anthony Hospital

    Oklahoma City, Oklahoma 73101
    United States

    Site Not Available

  • St. John Medical Center

    Tulsa, Oklahoma 74104
    United States

    Site Not Available

  • CCOP - Columbia River Program

    Portland, Oregon 97213
    United States

    Site Not Available

  • Lehigh Valley Hospital

    Allentown, Pennsylvania 18103
    United States

    Site Not Available

  • St. Luke's Hospital Regional Cancer Center

    Bethlehem, Pennsylvania 18015
    United States

    Site Not Available

  • Geisinger Medical Center

    Danville, Pennsylvania 17822-2001
    United States

    Site Not Available

  • Mercy Catholic Medical Center, Mercy Fitzgerald Divison

    Darby, Pennsylvania 19023
    United States

    Site Not Available

  • Delaware County Memorial Hospital

    Drexel Hill, Pennsylvania 19026
    United States

    Site Not Available

  • Penn State Geisinger Cancer Center

    Hershey, Pennsylvania 17033
    United States

    Site Not Available

  • Albert Einstein Cancer Center

    Philadelphia, Pennsylvania 19141
    United States

    Site Not Available

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania 19111
    United States

    Site Not Available

  • Hahnemann University Hospital

    Philadelphia, Pennsylvania 19102-1192
    United States

    Site Not Available

  • Kimmel Cancer Center of Thomas Jefferson University - Philadelphia

    Philadelphia, Pennsylvania 19107
    United States

    Site Not Available

  • University of Pennsylvania Cancer Center

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Philadelphia

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • Mercy Hospital of Pittsburgh

    Pittsburgh, Pennsylvania 15219
    United States

    Site Not Available

  • University of Pittsburgh Cancer Institute

    Pittsburgh, Pennsylvania 15213
    United States

    Site Not Available

  • Western Pennsylvania Hospital

    Pittsburgh, Pennsylvania 15224
    United States

    Site Not Available

  • Reading Hospital and Medical Center

    Reading, Pennsylvania 19612-6052
    United States

    Site Not Available

  • Mercy Hospital Cancer Center - Scranton

    Scranton, Pennsylvania 18501
    United States

    Site Not Available

  • Wilkes Barre General Hospital

    Wilkes-Barre, Pennsylvania 18764
    United States

    Site Not Available

  • CCOP - MainLine Health

    Wynnewood, Pennsylvania 19096
    United States

    Site Not Available

  • York Hospital

    York, Pennsylvania 17315
    United States

    Site Not Available

  • Roger Williams Medical Center/BUSM

    Providence, Rhode Island 02908-4735
    United States

    Site Not Available

  • Medical University of South Carolina

    Charleston, South Carolina 29425-0721
    United States

    Site Not Available

  • CCOP - Greenville

    Greenville, South Carolina 29615
    United States

    Site Not Available

  • CCOP - Upstate Carolina

    Spartanburg, South Carolina 29303
    United States

    Site Not Available

  • Rapid City Regional Hospital

    Rapid City, South Dakota 57709
    United States

    Site Not Available

  • Jackson-Madison County General Hospital

    Jackson, Tennessee 38301
    United States

    Site Not Available

  • Baptist Regional Cancer Center - Knoxville

    Knoxville, Tennessee 37901
    United States

    Site Not Available

  • CCOP - Baptist Cancer Institute

    Memphis, Tennessee 38117
    United States

    Site Not Available

  • University of Tennessee, Memphis Cancer Center

    Memphis, Tennessee 38103
    United States

    Site Not Available

  • Vanderbilt Cancer Center

    Nashville, Tennessee 37232-6838
    United States

    Site Not Available

  • Harrington Cancer Center

    Amarillo, Texas 79106
    United States

    Site Not Available

  • Julie and Ben Rogers Cancer Institute

    Beaumont, Texas 77701
    United States

    Site Not Available

  • University of Texas Medical Branch

    Galveston, Texas 77555-1329
    United States

    Site Not Available

  • University of Texas - MD Anderson Cancer Center

    Houston, Texas 77030-4009
    United States

    Site Not Available

  • Wilford Hall - 59th Medical Wing

    Lackland Air Force Base, Texas 78236-5300
    United States

    Site Not Available

  • Joe Arrington Cancer Research and Treatment Center

    Lubbock, Texas 79410-1894
    United States

    Site Not Available

  • Bayshore Medical Center

    Pasadena, Texas 77504
    United States

    Site Not Available

  • East Texas Medical Center - Cancer Institute

    Tyler, Texas 75701
    United States

    Site Not Available

  • Dixie Regional Medical Center

    Saint George, Utah 84770
    United States

    Site Not Available

  • LDS Hospital

    Salt Lake City, Utah 84143
    United States

    Site Not Available

  • University of Utah Health Sciences Center

    Salt Lake City, Utah 84132
    United States

    Site Not Available

  • CCOP - Southwestern Vermont Regional Cancer Center

    Bennington, Vermont 05201
    United States

    Site Not Available

  • Vermont Cancer Center

    Burlington, Vermont 05401-3498
    United States

    Site Not Available

  • Green Mountain Oncology Group

    Rutland, Vermont 05701
    United States

    Site Not Available

  • Cancer Center, University of Virginia HSC

    Charlottesville, Virginia 22908
    United States

    Site Not Available

  • Martha Jefferson Hospital

    Charlottesville, Virginia 22901
    United States

    Site Not Available

  • RMH Regional Canter Center

    Harrisonburg, Virginia 22801
    United States

    Site Not Available

  • Virginia Baptist Hospital

    Lynchburg, Virginia 24503
    United States

    Site Not Available

  • Naval Medical Center, Portsmouth

    Portsmouth, Virginia 23708-2197
    United States

    Site Not Available

  • Swedish Cancer Institute

    Seattle, Washington 98104
    United States

    Site Not Available

  • Virginia Mason Medical Center

    Seattle, Washington 98111
    United States

    Site Not Available

  • Deaconess Medical Center

    Spokane, Washington 99210-0248
    United States

    Site Not Available

  • Yakima Valley Memorial Hospital

    Yakima, Washington 98902
    United States

    Site Not Available

  • Schiffler Cancer Center

    Wheeling, West Virginia 26003
    United States

    Site Not Available

  • St. Vincent Hospital

    Green Bay, Wisconsin 54307-3508
    United States

    Site Not Available

  • Gundersen Lutheran Medical Foundation

    La Crosse, Wisconsin 54601
    United States

    Site Not Available

  • Southern Wisconsin Radiotherapy Center

    Madison, Wisconsin 53713
    United States

    Site Not Available

  • University of Wisconsin Comprehensive Cancer Center

    Madison, Wisconsin 53792
    United States

    Site Not Available

  • Marshfield Clinic

    Marshfield, Wisconsin 54449
    United States

    Site Not Available

  • Community Memorial Hospital

    Menomonee Falls, Wisconsin 53051
    United States

    Site Not Available

  • Columbia Hospital

    Milwaukee, Wisconsin 53211
    United States

    Site Not Available

  • Medical College of Wisconsin

    Milwaukee, Wisconsin 53226
    United States

    Site Not Available

  • St. Joseph's Hospital

    Milwaukee, Wisconsin 53210
    United States

    Site Not Available

  • St. Luke's Medical Center

    Milwaukee, Wisconsin 53215
    United States

    Site Not Available

  • Veterans Affairs Medical Center - Milwaukee (Zablocki)

    Milwaukee, Wisconsin 53295
    United States

    Site Not Available

  • Southeastern Wisconsin Regional Cancer Center

    Racine, Wisconsin 53405
    United States

    Site Not Available

  • Waukesha Memorial Hospital

    Waukesha, Wisconsin 53188
    United States

    Site Not Available

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