Phase
Condition
Hearing Loss
Deafness
Hearing Impairment
Treatment
N/AClinical Study ID
Ages 18-70 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Have sensorineural (nerve/inner ear) hearing loss of at least 30 dB in each ear, whichhas rapidly progressed.
Are in good general health.
Are sterile or use contraception (if a woman of child-bearing age).
Are able to speak and understand English or Spanish.
Exclusion
Exclusion Criteria:
Have had any previous reaction to prednisone, or history of psychiatric reaction tocorticosteroids.
Have used corticosteroids for more than 30 days within the past 90 days. Patients whohave been off corticosteroids for at least 30 days may be eligible.
Have any significant heart, lung, digestive, blood, or neurologic disorders.
Have tuberculosis (TB), brittle or unstable insulin-dependent diabetes mellitus,active malignancy or prior chemotherapy, pancreatitis, active peptic ulcer disease,kidney failure, history of shingles, or known (other) autoimmune disease.
Have had a positive test for HIV, hepatitis C or B.
Have any type of middle ear disorder.
Are breast-feeding or pregnant.
Study Design
Connect with a study center
House Ear Institute
Los Angeles, California 90057
United StatesSite Not Available
UCSD Medical Center
San Diego, California 92103-8895
United StatesSite Not Available
Univ of Iowa Hosp and Clinic
Iowa City, Iowa 52242-1078
United StatesSite Not Available
Johns Hopkins Univ
Baltimore, Maryland 21287-0008
United StatesSite Not Available
Massachusetts Eye and Ear Infirmary
Boston, Massachusetts 02114
United StatesSite Not Available
Univ of Michigan
Ann Arbor, Michigan 48109-0005
United StatesSite Not Available
New York University
New York, New York
United StatesSite Not Available
Cleveland Clinic Foundation
Cleveland, Ohio 44195-5245
United StatesSite Not Available
University of Texas, Southwestern Medical Center at Dallas
Dallas, Texas
United StatesSite Not Available
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