University of Kentucky Chandler Medical Center

Center Information

Philip Kern, MD
Professor of Medicine, Division of Endocrinology
University of Kentucky Chandler Medical Center
Director, Center for Clinical and Translational Sciences
800 Rose Street, C-347
Lexington, Kentucky 40536-0293
859-257-3687 (fax)

Site Marketing Contact for Information on Investigators and Research Studies:
Roxane L. Poskin
Manager, Participant Recruitment & Marketing
Lexington, KY 40536-0284

Currently Enrolling Trials

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Therapeutic Areas

Cardiology/Vascular Diseases
Dental and Oral Health
Genetic Disease
Healthy Volunteers
Hepatology (Liver, Pancreatic, Gall Bladder)
Infections and Infectious Diseases
Internal Medicine
Nutrition and Weight Loss
Obstetrics/Gynecology (Women’s Health)
Orthopedics/Orthopedic Surgery
Otolaryngology (Ear, Nose, Throat)
Plastic Surgery
Pulmonary/Respiratory Diseases
Trauma (Emergency, Injury, Surgery)


The University of Kentucky Chandler Medical Center (UKCMC) is one the nation’s finest academic health care centers. Its vision is to be a Top-20 academic health center recognized nationally and internationally for excellence in teaching, research and patient care - Top 10 Business Plan.

The University of Kentucky is achieving outstanding success in the competitive arena of research grants & contracts (see Research statistics and national rankings). Major research areas include Aging, Behavioral Health, Cancer, Drug Evaluation, Infection and Immunity, Endocrinology, Gastroenterology, Surgery, Neurosciences, Spinal Cord Injuries, and Women's Health.

Center for Clinical and Translational Science (CCTS): Established by the Board of Trustees as a University-wide center in September 2007, the Center for Clinical and Translational Science (CCTS) at the University of Kentucky (UK) is leading the alignment of UK’s ongoing transformation of its entire clinical and translational research enterprise with the goals of the NIH Roadmap Clinical and Translational Science Award (CTSA). The overall goal of the CCTS is to accelerate the translation of basic science advances to tangible improvements in the public’s health, addressed in four specific aims:
Specific Aim 1: Enhance and develop new outreach pathways to confront chronic health issues in rural Appalachia, ensuring that our research addresses community concerns and that the community benefits from our findings.
Specific Aim 2: Develop the clinical and translational research programs of the future using innovative methods to champion collaborative team science.
Specific Aim 3: Enhance existing educational pathways and develop novel methods to educate and excite the next generation of collaborative clinical and translational scientists.
Specific Aim 4Strengthen the development of biomedical informatics and novel methodologies through improved cross-disciplinary collaboration.

The CCTS now encompasses the Clinical Services Cores (CSC), which resulted from the integration of the former UK Clinical Research Organization (UKCRO) and UK’s General Clinical Research Center (GCRC). Along with eight other key functions, CSC provides a centralized infrastructure consisting of key core facilities and services to help investigators, clinicians, and scholars from across the University and the Commonwealth of Kentucky to access much needed resources to become educated on the conduct of clinical research, and to afford them mechanisms to access a gamut of support services needed for the conduct of high quality clinical and translational research. These services do not end at the boundaries of the University of Kentucky campus, but reach across the Commonwealth engaging greater partnership between the communities, industry, and the University. Information on the CCTS Web site details the core facilities housed within the CCTS, with links to other services


UKMC encompasses the following:

UKCMC also includes world-renowned centers

CCTS Clinical Services Core (CSC) was established to promote and expand the UKMC clinical research. The CSC is conveniently located on the floor of UKMC, this 3,985 square foot facility provides ample space to conduct outpatient trials and short-term pharmacokinetic studies. CSC also occupies 5,954 square foot of space in the newly remodeled Research Inpatient Clinic on the 3rd floor of the hospital. The CSC will build on the past success to become all encompassing service center -The Clinical Services Core (CSC) through the Center for Clinical Translational Science (CCTS). These facilities' resources are available to all clinical investigators throughout the University.


  • To promote and facilitate clinical trials
  • To provide regulatory and administrative services
  • To provide inpatient an outpatient coordination of all phase clinical trials
  • Assist faculty and provide expertise in investigator initiated projects
  • Improve and monitor clinical research compliance
  • Provide clinical research training

Outpatient amenities include:

  • Located on 3rd floor of UKMC
  • Reception Area, six exam rooms, and a procedure/phlebotomy room
  • Lab processing and shipping area
  • Designated monitoring areas with remote computer connections
  • Charting areas
  • Refrigerator available for patient food or medications

Inpatient amenities include:

  • Located on the 5th floor of the UKMC
  • Fully staffed nursing unit
  • 15- inpatient beds unit (8 rooms)
  • Lab processing and shipping area
  • Metabolic Kitchen

Biochemical Analysis Laboratory:

  • Methodology consultation and novel assay development
  • Performs assays not routinely available through the Hospital Clinical Laboratory, e.g. cytokines, growth factors, hormones
  • Capabilities to run assays on the Luminex, Affymetrix gene array, Immulite, chemiluminescence plate reader, and endotoxin analysis
  • Networked with other laboratories greatly enhancing assay capability

Functional Assessment and Body Composition Core:

  • Methodology and Anaylsis consultation
  • Exercise Physiolology lab (DEXA, BodPod, PFT, metabolic cart, GXT, treadmill and bicycle ergometry, BIA)

Delta Dental of Kentucky Clinical Research Center:

  • DXA
  • Anthropometry
  • BIS
  • Resting and exercise blood pressure
  • 12 lead ECG
  • Treadmill and bicycle ergometry
  • Breadth by breath oxygen consumption
  • Basal metabolic rates
  • PFT


Research/therapeutic areas:

To learn more about ongoing clinical research at the UK Academic Medical Center, please refer to the following


The University of Kentucky is centrally located in the scenic rolling hills of the Bluegrass.

(For descriptions, including photos, of some of UKCMC's facilities, see Facilities

The Lexington, Kentucky campus includes:

Programs and Services

Travel and Lodging Information


Lexington Convention and Visitors Bureau
301 East Vine Street
Lexington, Kentucky 40507
(859) 233-7299


Bluegrass Airport
4000 Versailles Road


Yellow Cab Taxicabs

Campus Guide

Campus Map


The UK Medical Center is supported by more than 500 faculty physicians and dentists, 517 resident physicians and a staff of 3,200 health professionals committed to high-quality patient care. It has created an appealing environment to attract, reward and retain outstanding, multi-disciplinary clinical research personnel. Coordinator certification serves as a means of advancement. More than 75% of the currently employed Clinical Research Coordinators and Clinical Research Associates are certified, with many others in the process of obtaining certification. Proactive educational and training series are offered to ensure staff knowledge, skills and compliance with good clinical practice guidelines.


Kentucky has a population of 4,380,415. The UK Chandler Medical Center provides health care to residents of all (120) Kentucky counties and surrounding states, (Kentucky and Regional Demographics). Much of the regional area is rural and consists of stable, non-transient people, with a high incidence of major chronic diseases. Patient contacts for 1998 included more than 20,000 admissions, 35,000 emergency department visits, and 368,000 outpatient visits. Disease demographics may be readily obtained for determination of potential subject pools.

Lexington, KY Community Profile.

Kentucky is in the middle of the "Coronary Valley" - a name given to areas with the highest rates of coronary heart disease.

Kentucky’s ranking in disease areas in comparison to other states in the nation:

  • 27% of adult Kentuckians smoke (KY is ranked #1 in nation)
  • 27% report no physical activities (#2)
  • 33% report not using seat beats (#3)
  • 38% are overweight; 24% are obese (#6)
  • 9% of adults are diabetic (#7)
  • 68% of individuals over the age of 65 are immunized (#11)
  • Kentucky ranks 13th nationally in premature deaths
  • 65% have a high school education (#14)
  • Kentucky ranks 32nd nationally in the adequacy of prenatal care
  • 27% of women who are pregnant continue to smoke while pregnant
  • 43% of the 411 counties in the U.S. classified as high persistent poverty counties are located in Kentucky, all among the 51 counties in Kentucky that are located in Appalachian Eastern Kentucky.
  • Cardiovascular disease in the leading cause of death in Kentucky
  • 20 counties have Chronic Heart Disease mortality rates 25% higher than the national average
  • Kentucky is ranked 3rd highest in cancer mortality rates
  • Cancer rates for Incidence and Mortality by county (source 2007 Kentucky Cancer Registry)
  • Kentucky is ranked 5th in the nation in deaths from coronary heart disease and overall cardiovascular disease
  • Kentucky is ranked 6th as one of the nation’s worst location of allergies
  • In most cases, serious health problems in Kentucky can be explained by its heavy smoking rate (one of the highest in the nation)
  • Map of Adult Kentucky Illicit Drug Use Population
  • Incidence of Mental stress, depression and emotional problems in the Adult Kentucky Population


Other sites of interest at UK include:

For Clinical Research Participants:
See our research study registries at:
Clinical Research Opportunities Wildcat Database (CROWD)

For other studies across the Nation see:

If you are interested in contacting this academic medical research center to discuss participating in a clinical research study or if you are a Pharmaceutical Company or CRO looking for a research investigator to conduct a potential research study, please complete and submit the e-mail form below. A representative from the research center will then follow up with you.

Contact Center

If you are interested in contacting this center to discuss clinical trials, please complete and send the email form below. A representative from the research center will then follow up with you.