Clinical Eye Research Center of Connecticut

Center Information

Angela Smit, CCRP
Clinical Research Coordinator
Clinical Eye Research Center of Connecticut
69 Sand Pit Road, Suite 101
Danbury, CT 06810
203-791-2020 ext. 256

Currently Enrolling Trials

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Therapeutic Areas

Plastic Surgery


Danbury Eye Physicians and Surgeons, P.C. is a physician owned, multi-specialty, ophthalmology group practice. We are dedicated to the organization, ethical performance and timely completion of quality clinical investigational drug trials. Our highly trained professional staff has a common goal to promote the development of effective and safe medical products through Good Clinical Practices. This mission is accomplished through devoted patient-physician interaction and education. We provide patients with the opportunity to have access to new medications, which could dramatically improve their quality of life. Danbury Eye Physicians and Surgeons has the capability to participate in phase I, II, III and IV research trials on an outpatient basis.


We have been participating in clinical trials for over 15 years. We have conducted trials in phases I, II, III and IV. Our clinical research trials have included the following sponsors and CROs:

Alcon, Allergan, Astra Zeneca, Bausch & Lomb, CIBA Vision Corporation, Covance, CroMedica, Human Resource Management Inc., InSite Vision, ISTA Pharmaceuticals Inc., Lexitas, MedTap International, Merck, Ophthalmic Research Associates, Parke-Davis, Daiichi, Pharmacia Corporation, Inspire Pharmaceuticals, Genentech, Genaera, Redox Pharmaceuticals, Pfizer, Sirion Therapeutics, Novartis, OLT Inc., Oculos, Shire, Chiltern, Ohr, and WCCT Global.


Danbury Eye Physicians and Surgeons is located in Southwestern Connecticut in Fairfield County. Our Danbury office is situated less than one-mile from Danbury Hospital and offers convenient parking. Along with all our ophthalmic specialties (General Ophthalmology, Cataract, Retina, Cornea, Glaucoma, Oculoplastics) our Danbury office is equipped with a full service optical shop and contact lens department. Our state of the art 15,300-square-foot facility houses a dedicated research area, 17 examination rooms, 9 pretest/history rooms, locked record room, study supply storage, PC systems for database development, wireless internet, and office management and administration space.

Danbury Eye also has a satellite retinal practice in Prospect CT and two satellite general ophthalmology practices in New Milford, CT and Westport, CT. In addition, we have ownership interest in Precision Laser in Cheshire, CT, an excimer and LASIK center, as well as a partnership interest in Danbury Surgical Center located within our medical complex. Danbury Surgical Center is fully equipped for comprehensive anterior and posterior surgical eye procedures.

A minimum of 1,000 patients are examined weekly, with at least 200 new patients added to our practice a week, Danbury Eye currently has over 150,000 patient charts.

Danbury Eye currently has the following testing procedures and equipment available on site:
  • Haag-Streit Slit Lamps
  • Zeiss Slit Lamps
  • 2 Humphrey Perimeters with the “SITA” Program
  • Goldman Applanation Tonometers, Handheld Perkins Tonometer and Tonopen
  • Reichert 7 Auto Tonometer
  • Zeiss FF450 Fundus and Anterior Segment Photography (Digital)
  • Oculus Z Pentacam HR
  • Ultrasound - A and B Scan
  • Specular Microscopy
  • Portable Operating Room Microscope
  • CompuScan UPC-1000 Pachymetry Unit
  • Heidelberg Spectralis Fluorescein and OCT
  • Zeiss HK 7000 Laser
  • YAG Laser
  • 4 Marco Epic Refraction Systems
  • Contrast Sensitivity
  • Brightness Acuity Testing
  • Color Vision Testing
  • Zeiss Cirrus 4 OCT


    Our highly qualified physician investigators have an extensive variety of background specialties with exemplary community reputations and significant patient databases. Additionally, two of our investigators are Certified Principal Investigators with a proven track record of regulatory compliance.

    The following physicians are associated with Danbury Eye Physicians and Surgeons. Curriculum Vitaes for our Investigators are available upon request.

    Bruce Altman, MD
    Glaucoma Specialist

    Eitan Burstein, MD
    Glaucoma Specialist

    Armand Daccache, MD
    Retina Specialist

    Ralph J. Falkenstein, MD
    General Ophthalmology and Cataract Specialist

    Anisha Jangi, MD
    General Ophthalmology, Cornea, Refractive Surgery and External Disease Specialist

    Archna Johar, MD
    General Ophthalmology, Corneal and External Disease Specialist, and Refractive Surger

    Stephen A. Mathias, MD,
    Pediatric and Strabismus Specialist

    Matthew D. Paul, MD, F.A.C.S., FAAO, CPI, FAPRC
    General Ophthalmology, Cataract Specialist

    Paul J. Ruggiero, MD
    General Ophthalmology and Cataract Specialist

    Richard Scartozzi, MD, FACS, FICS, FAAO, CPI, FAPRC
    Retina Specialist

    Katherine J. Zamecki, M.D.
    General Ophthalmology and Plastic Surgery

    Stephen Zuckerman, MD
    General Ophthalmology, Corneal and External Disease Specialist, and Refractive Surgery

    Margaret Marcone, OD
    Pediatric Optometry and Contact Lens Specialist

    Yuan Tran, OD
    General Optometrist and Contact Lens Specialist

    Angela Smit, BS, CCRP
    Research Coordinator


    Danbury Eye Physicians and Surgeons has a dedicated Clinical Research Coordinator as well as Assistant Research Coordinators and technical Staff. Our Research team members are experienced in research, efficient and , caring professionals who are well trained to treat study participants with respect and dignity. Their constant interaction with the Investigators assists in keeping the study enrollment on target, and documentation and correspondence timely to provide the Sponsor with clean, accurate data.


    Our research population includes rural, urban and suburban patients ranging from infants to the elderly. The greater Danbury area also offers a diverse ethnic population. Danbury Eye Physicians and Surgeons recognizes the success of every clinical trial hinges on the success of the recruiting strategies for identifying qualified and compliant patients. Our research center uses a variety of tailored recruitment methods including ICD-10 database searches, chart review, physician and community education, and traditional advertising that provides a broad knowledge base about our enrolling studies. This assures enrollment goals are met and clinical trials are successfully completed.

    Contact Center

    If you are interested in contacting this center to discuss clinical trials, please complete and send the email form below. A representative from the research center will then follow up with you.