Nisus Research, McLaren Northern Michigan

Center Information

Lisa Rogers
Department Coordinator
Nisus Research, McLaren Northern Michigan
416 Connable Ave
Petoskey, MI 49770

Currently Enrolling Trials

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Therapeutic Areas

Cardiology/Vascular Diseases
Hepatology (Liver, Pancreatic, Gall Bladder)

Performance Metrics

Number of Studies Conducted: 275+
Number of Studies Actually Completed: 275+
Number of Active Patients in the Database: 125+
Regulatory Submission Turn-Around Time: 4 Week(s)
Average Number of Total Patients Enrolled: 20
Average Percent of Total Patients Randomized: 99%
Average Percent of ‘Completed’ Studies that met Enrollment Goals: 95%
EDC Capabilities: Yes


Nisus Research, a department of McLaren Northern Michigan, is located in Petoskey, Michigan. Since 1984, Nisus Research has been conducting clinical trials for Phase II, Phase III and Phase IIIb/IV drug and device trials. The dedicated and experienced research staff works in collaboration with more than 200 multi-specialty physicians, affiliated with McLaren Northern Michigan.

Nisus Research allows access to new therapies and diagnostics as a unique compliment to the high level of care, offered to patients utilizing this regional referral center.

Nisus Research provides administrative and study coordinator support to physicians in the conduct of clinical trials. These trials interface well with the inpatient and outpatient medical care provided by our experienced physicians.

The name, “Nisus” means to “endeavor or strive”. It was chosen based on the department’s mission to support the good health of area residents, by providing them with a quality research program. To date, Nisus has conducted over 270 clinical trials with more than 2050 volunteer participants.


We have conducted trials in the following areas:

  • Acute Coronary Syndrome
  • Atrial Fibrillation
  • Breast Cancer
  • Carotid Stenting
  • Cellulitis
  • Congestive Heart Failure
  • Coronary Artery Bypass Surgery
  • Coronary Artery Disease
  • Deep Vein Thrombosis
  • Deep Vein Thrombosis Prevention
  • Diabetes
  • Dialysis
  • Hepatitis C
  • Hip Fracture
  • Hyperlipidemia
  • Hypertension
  • Lung Cancer
  • Myocardial Infarction
  • Pacemaker
  • Pulmonary Embolism
  • Osteoarthritis
  • Osteoporosis
  • Pancreatic Cancer
  • Renal Failure
  • Rheumatoid Arthritis
  • Peripherial Vascular Disease
  • Pneumonia
  • Shingles
  • Total Knee Replacement
  • Total Hip Replacement
  • Wrist Fracture

We have worked with the following sponsors and CROs:

  • Abbott
  • Akzo Nobel
  • Alexion
  • Anthera
  • Amgen
  • Aphton
  • Arginox
  • A.R. Kamm
  • Astra Zeneca
  • Aventis
  • Basilea
  • Bayer
  • Boehringer-Ingelheim
  • Boots
  • Brigham/Women’s Hospital
  • Bristol-Myers Squibb
  • BurroughsWellcome
  • Cancer Trials Support Group
  • Cardiac Pacemaker
  • Cardiome
  • Chrysalis
  • Ciba-Geigy
  • Cordis
  • Corgentec
  • Cor Therapeutics
  • Covance
  • CVT Therapeutics
  • DuPont
  • Duke Clinical Research
  • Eli Lilly
  • Episphere
  • Fauulding
  • G.D. Searle
  • G.H. Besselaar
  • Genentec
  • Glaxo
  • Hoechst-Roussel
  • Hesperion
  • Hoffman-LaRoche
  • ICON
  • J and J
  • Kendle
  • Knoll
  • Lundbeck
  • Luitpold
  • Medtronic
  • Millenium
  • Merck
  • Novartis
  • Orthologic
  • Otsuka
  • Pfizer
  • Pharmanet
  • Proctor & Gamble
  • Quintiles
  • Sanofi-aventis
  • Schering-Plough
  • Smith –Kline Beecham
  • Southwest Oncology Group
  • The National Surgical Adjuvant Breast and Bowel Project
  • The Gynecological Oncology Group
  • Takeda
  • TIMI Study Group
  • Upjohn
  • Vasogen
  • Yamanouchi


McLaren Northern Michigan, and nearby multi-specialty physician offices are located on Lake Michigan’s Little Traverse Bay. We offer experienced clinical trial capabilities in both inpatient and outpatient studies, in numerous therapeutic areas.

  • 202 licensed bed regional referral center
  • ICU, CVU, Emergency Department
  • Over 200 multi-specialty physicians, with staff privileges
  • Open heart surgery, state-of-the-art Cardiac Catheterization and Electrophysiology Laboratory
  • EKG, Holter monitoring, Treadmill, Transesophageal Echocardiography, Nuclear Imaging
  • Dedicated clinical research coordinators and an administrative assistant
  • CLIA / CAP certified laboratory
  • Comfortable patient waiting areas and exam rooms
  • Daily Express courier pick-up
  • Remote data entry capabilities
  • High speed fax on dedicated line
  • Comprehensive telephone system with voicemail and physician direct service
  • High speed internet, with E-mail
  • On-site patient record accessibility

Nisus Research occupies a locked, limited access area with secured cabinets for storage of study drug. We are located 4 ½ hours northwest of Detroit, and are easily accessible by both the Pellston and Traverse City Airports.


Nisus Research provides well versed physicians whose specialty areas of expertise and interest are extensive:

Harry T. Colfer, M.D. : 29 years Clinical Research Experience

Mark C. Antonishen, M.D. : 21 years Clinical Research Experience

H. Gunner Deery, II, M.D. : 17 years Clinical Research Experience

Irene Kazmers, M.D. : 10 years Clinical Research Experience

Andrew Teklinski, M.D. : 9 years Clinical Research Experience

Andris Kazmers, M.D. : 10 years Clinical Research Experience

Dalton Miranda, M.D. : 7 years Clinical Research Experience

  • Cardiovascular
  • Dermatology
  • Emergency
  • Endocrinology
  • General Vascular Surgery
  • Infectious Disease
  • Internal Medicine
  • Nephrology
  • Neurology
  • Obstetrics / Gynecology
  • Oncology/ Hematology
  • Ophthalmology
  • Othopaedics
  • Radiation Therapy
  • Plastic Surgery
  • Pulmonary Medicine
  • Rheumatology
  • Urology


The Nisus Research staff is experienced in a variety of areas offering more than 25 years of nursing experience. The research study coordinators are Certified Clinical Research Coordinators (CCRC) through the Association of Clinical Research Professionals.

The Nisus Research staff includes:

Denise Antonishen, RN, BSN, CCRC
Research Study Coordinator

Colleen M. Shaw, RN, BSN, CCRC
Research Study Coordinator

Barbara E. Stone, RN, MSN, CCRC
Research Study Coordinator

Peggy Ward, RN, CCRC
Research Study Coordinator

Suzanne VanAlstyne
Department Coordinator

Lisa Rogers
Department Coordinator


Nisus Research recruits study participants from a population of more than 350,000 residents, from Northern Michigan and the Upper Peninsula, encompassing 24 counties.

Contact Center

If you are interested in contacting this center to discuss clinical trials, please complete and send the email form below. A representative from the research center will then follow up with you.