Internal Medicine Research

Center Information

Mark Stephens, CMR, PAHM
Consultant - Research Business Development
Internal Medicine Research
2300 Randolph Road Suite A
Charlotte, NC 28207

Currently Enrolling Trials

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Therapeutic Areas

Cardiology/Vascular Diseases
Internal Medicine
Otolaryngology (Ear, Nose, Throat)
Pulmonary/Respiratory Diseases

Performance Metrics

Number of Studies Conducted: 44
Number of Studies Actually Completed: 36
Number of Active Patients in the Database: 15000
Regulatory Submission Turn-Around Time: 2 Week(s)
Average Number of Total Patients Enrolled: 25
Average Percent of Total Patients Randomized: 95%
Average Percent of ‘Completed’ Studies that met Enrollment Goals: 97%
EDC Capabilities: Yes


Our research program is a culturally diverse private practice center with a specialty in Internal Medicine. We provide both office-based and hospital-based care in a moderate sized Southern city. We are privately owned and operated but have staff associations with two large hospital systems.

Metrolina Internal Medicine, P.A. was established in 1999 as a two physician group and has since grown to include multiple physicians in two locations. Our practice emphasis is on primary care with special emphasis on hypertension, diabetes, asthma and other chronic adult illnesses.

Internal Medicine Research grew out of this practice and has become an important and vital part of the organization. We strive to actively conduct clinical trials for contribution to the body of medical knowledge and for the eradication of health disparities.


Our center has 17 years of experience and specializes in trials related to all common chronic adult disease processes including:

  • Hypertension
  • Type II Diabetes
  • Asthma/COPD
  • Hypercholesterolemia
  • Degenerative Joint Disease
  • Obesity
  • Type II Diabetes/DKD
  • Anemia
  • Type II Diabetes/DKD
  • Ulcerative Cholitis
  • Chronic Pain
  • HIV

Past Sponsors/CROs

  • Novartis
  • Pfizer
  • Wyeth
  • GlaxoSmithKline
  • Astra Zeneca
  • Bristol-Myers Squibb
  • Amgen
  • Abbott
  • Gilead
  • Sanofi-Aventis
  • PPD
  • Kendle
  • Premier Research
  • NovoNordisk
  • Careers In Research
  • Takeda
  • Boehringer Ingerlheim
  • ICON
  • Esai
  • BayerHealthcare
  • Armetheon
  • Ardelyx
  • DCRI
  • Actelion


We offer outpatient facilities and have access to an inpatient outpatient popultion.

Our center offers on-site electrocardiography, echocardiography, spirometry and vascular testing.

Our offices are adjacent to hospital facilities and are readily accessible to public transportation.

On site Lab

-20 Freezer



Located .1 mile from Major Hospital


Clarence O. Ellis, MD
Board Certified Internal Medicine

Karlton S. Pettis, MD
Board Certified Internal Medicine

Both physicians have served as Principal Investigators and Sub-Investigators in various clinical trials and have 14 or greater years of clinical research experience.

Karlton Pettis, MD

Dr. Pettis is board certified by the American Board of Internal Medicine. He has practiced medicine for 18 years. Dr Pettis is a graduate of the University of North Carolina School of Medicine. His post graduate medical training was completed at the Baylor College of Medicine. He is a former Clinical Research Associate at Duke Clinical Research Institute and has published clinical trials.

Clarence Ellis, MD

Dr. Ellis is board certified by the American Board of Internal Medicine. He has been practicing medicine in Charlotte since 1984, and is graduate of the University of North Carolina at Chapel Hill, School of Medicine. He received his residency training at the Medical College of Virginia Hospitals.


Mark Stephens
Consultant - Research Business Development

Felecia Brown
Certified Clinical Research Coordinator
> 9 years of clinical research experience

Samantha Jamison
Certified Clinical Research Coordinator
> 5 years of clinical research experience


This practice serves both urban and suburban populations in two office locations. The mean patient age is approximately 50 years, and the practice has substantial numbers of elderly patients with a variety of chronic illnesses. The practice is ethnically diverse and serves a large African-american cohort.

Contact Center

If you are interested in contacting this center to discuss clinical trials, please complete and send the email form below. A representative from the research center will then follow up with you.