The Clinical Research Center, LLC

Center Information

The Clinical Research Center, LLC
1040 N. Mason Road, Suite 112
St. Louis, MO 63141

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Currently Enrolling Trials

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Therapeutic Areas

Internal Medicine
Pulmonary/Respiratory Diseases


The Clinical Research Center is located on the campus of  Barnes-Jewish West County Hospital and is a privately owned, dedicated clinical research site specializing in pharmaceutical research involving a wide range of illnesses. Our Principal Investigator, Dr. Jeffrey Tillinghast, MD, CPI, is board certified in Internal medicine and Immunology. Our 30+ years of experience conducting clinical trials in St. Louis has led us to be a premier research site in St. Louis. Our team of research professionals provide the highest quality of patient care along with the very best, accurate timely data that our network of sponsors and CRO’s are accustomed to. We have highly trained, GCP certified, research professionals in each area of the research process. This includes a seasoned professional for contracts/budgets, regulatory affairs, recruitment, advertising, and multiple Study coordinators, Our Study Coordinators are Registered Nurses and bring the highest level of critical thinking skills to the protocols, which provides the type of clinical data we can be proud. This structure allows us to move through conducting a clinical trial, from start to finish, in the fastest, most efficient way.

For more information, please visit The ClinicalResearch Center homepage.


Areas of Expertise:

  • Asthma
  • Allergies
  • Atopic Dermatitis
  • Dermatological Conditions
  • Chronic Bronchitis
  • Common Cold
  • COPD / Emphysema
  • GERD
  • Hives - Urticaria
  • Influenza
  • Inhaler Devices
  • Migraines
  • Psoriasis
  • Vaccines

The Clinical Research Center has been conducting clinical trials in St. Louis since 1991. Over 450 clinical trials have been performed and the knowledge we have gained from those trials only accentuate our current experience in providing timely, quality data in all areas of the research process. Regulations have changed over the years and being in front of all that is new is important to our team. We train regularly on clinical trials processes. Confidentiality, expert documentation, team work, and integrity allow us to exceed our goals. The Clinical Research Center takes on studies independently and through its membership with CRN/Allergy

We have experience with the following sponsors:

  • 3M Pharma
  • Abbott Labs
  • Actelion
  • Aerocrine
  • American Lung Association - ACRC
  • Alcon
  • ALK-Abello
  • Alkermes
  • Allergy Therapeutics
  • Altana
  • Amgen
  • Amphastar
  • Antigen
  • Apieron
  • Apotex
  • Astellas
  • AstraZeneca
  • Aventis
  • Bayer Pharmaceuticals
  • Biota
  • Boehringer Ingelheim
  • Bristol Meyers Squibb
  • Capnia
  • Centocor
  • Cephalon
  • Chiesi
  • Circassia
  • Clay-Park Labs
  • Critical Therapeutics
  • Curalogic A/S
  • Cytos
  • DEY
  • Dura
  • Dynavax
  • Epigenesis
  • F. Hoffmann-La Roche
  • Forest
  • Genentech
  • Glenmark
  • GSK
  • Hoechst Roussel Pharmaceuticals, Inc.
  • Hoffmann - La Roche
  • Icagen
  • ICI Pharma
  • IDEC
  • Immunex
  • IVAX
  • Janssen
  • Johnson & Johnson
  • Lupin
  • MannKind
  • Medicinova
  • MedImmune
  • MedPointe
  • Muro Astra Medica
  • Mylan (Dey)
  • Neurogen
  • Novartis
  • Oriel Therapeutics
  • PDL
  • Pearl Therapeutics
  • Perrigo
  • Pfizer
  • Pharmaxis
  • Regeneron
  • Renovo
  • Rhone-Poulenc Rorer (RPR)
  • Rigel
  • Romark
  • Roxane Laboratories
  • Salix
  • Sandoz
  • Sanofi-Aventis
  • Schering Plough
  • Sepracor
  • Shionogi
  • SkyePharma
  • Stallergenes
  • Sun Pharmaceutical
  • Sunovion (formerly Sepracor)
  • TAP
  • Teva
  • Theravance
  • UCB Pharma
  • Watson
  • WestWard
  • Whitehall-Robins
  • Wyeth
  • Zeneca
  • Zosano


The Clinical Research Center occupies 2,000 sq. feet of space, in Medical Building 1, on the campus of Barnes Jewish West County Hospital. Ample parking and two elevators in the building for easy access to our suite. We have a large, comfortable waiting room and wifi access for patients convenience. We have a separate laboratory for processing specimens, a 24 temperature-controlled room for the ambient drug. Ample locked, temperature-controlled, private space for study medication, binders, and records. Each Study Coordinator has its own office to do study visits. A larger comfortable, private, secondary waiting room area is designed for extended patient study visits with a large screen television including cable. This area includes snacks, refreshments, magazines and recliners for comfortable extended stays. Success and ease of overnight study visits by partnering with another facility.

Site equipment includes annually calibrated  pulmonary function equipment, site ECG, Body Box pulmonary equipment, Treadmill testing, Feno testing, nasal scans, chest x rays, negative 70 freezer,

The location at Barnes-Jewish West County Hospital campus provides access to everything the hospital has to offer. The center is easily accessible from St. Louis Lambert Airport and from St. Louis City and County. It is located less than one mile from inter-belt highway 270, which also provides access from St. Charles County and Illinois.


Dr. Jeffrey Tillinghast, MD
Certified Physician Investigator
Areas of Expertise: Allergy, Immunology and Internal Medicine(Board Certified)



Nancy Umbeck, RN, MSN
Executive Director

Sara Menees, RN, BSN
Study Coordinator
The professionals at The Clinical Research Center include a staff of ten. Our staff consists of a diverse group of highly educated and dedicated clinical research professionals. Our five Clinical Research Coordinators, who are all Registered Nurses, have several years of clinical trial experience and together have conducted over 300 clinical trials in all phases of drug development. The Clinical Research Center is dedicated to quality patient care and data collection.

Our staff includes an Executive Director who is an RN, MSN, responsible for contract and budgets, a Clinical Director, RN, BSN, who manages the day to day operations, a Regulatory Coordinator who handles IRB submissions and expedites the flow of paperwork in each of our studies; and a Recruiter, who manage our database of clinical research patients, handle advertising and recruit for enrolling studies.


The Clinical Research Center is located in the St. Louis Metropolitan area. We have a population in the St. Louis Metropolitan area of 2.5 million, this includes counties in southern Illinois and eastern Missouri on both sides of the Mississippi River. The Clinical Research Center has both pediatric and adult patients in our database. Our center is proud of its over 10,000 subjects who are interested in participating in our studies.Our retention rate is very high, as our patients are happy with their experience and are excellent research patients who are diligent and responsible.


If someone is interested in participating in a clinical trial our center will provide a pre-screening exam, at no cost, to determine eligibility. Along with the study trials the staff and coordinators educate the patient with regard to their particular illness. We also offer a “ refer a friend” program that gifts people with a gift card, who refer qualified patients int the center.

Contact Center

If you are interested in contacting this center to discuss clinical trials, please complete and send the email form below. A representative from the research center will then follow up with you.