Center InformationBetsy Moclair, RN, CCRC
Director, Clinical Research Programs
Northwell Health -North Shore University Hospital- Neurosurgery
300 Community Drive
Manhasset, NY 11030
Currently Enrolling Trials
North Shore University Hospital is one of the top hospitals in Long Island and The Department of Neurosurgery is one of the metro area's largest neurosurgical programs. We have an experienced research team and operate clinical trials that are both federal and industry sponsored. As a large academic medical center we are capable of participating in inpatient trials as well as outpatient at our local physician practices.
Our site has an interest in federal and industry sponsored trials for: Brain tumors • Neurotrauma • Trigeminal nerve stimulation for balance disorders • Acute subdural hematomas • Subarachnoid hemorrhage • Concussion • Neurovascular (carotids, endovascular coiling) • Epilepsy • Surgery for epilepsy • Intracerebral hemorrhage (ICH) • Stroke • Degenerative spine • Spasticity • Surgery for pain • Traumatic brain injury . We have worked with the NIH, Strokenet and sponsors that include Penumbra, Biogen, Helius, Pfizer, Fziomed, Medtronic, Idorsia, Novartis, Vesalio, Siemens, Electrocore, Microvention, Orbus, Synaptive and Hyperfine
On-site resources include refrigerated centrifuge, -70 and -20 freezer (continuous temperature monitoring with alarms), MRI, CT, Dexa. Our sites have access to locked medication cabinets with thermometers, and locked storage for research binders. There is an ability to utilize research pharmacists for more complex trials. There is also experience with the utilization of both local and central core labs. All of our laboratories are both CLIA and CAP certified. All of our equipment is biomed inspected. We have a 16 bed neurosurgical ICU staffed 24/7, stroke unit, dedicated epilepsy monitoring unit, 4 neurosurgical operating rooms, 1 hybrid operating room and 2 neurointerventional rooms.
Raj Narayan, MD
Dr. Raj Narayan is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery
Specialty/ Research Interest - Traumatic brain injury, brain neoplasms - hydrocephalus, normal pressure - hyperhidrosis disorder - spinal cord diseases - traumatic brain injury - neurotrauma - spinal disorders - brain tumors - normal pressure hydrocephalus - hyperhidrosis
Henry Woo, MD
Dr. Henry Woo is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery.
Specialty/ Research Interest - Ischemic and hemorrhagic stroke, endovascular (interventional) treatment of cerebral aneurysms - interventional radiology - stenting of carotid artery stenosis - cerebrovascular accident - subarachnoid hemorrhage - neuroradiology - cerebrovascular - cerebrovascular operation - cerebrovascular surgery - stroke
Jamie Ullman, MD
Dr. Jamie Ullman is a Neurosurgeon with North Shore University Hospital. She is board certified in Neurological surgery as well as Critical Care Medicine.
Specialty/ Research Interest - cerebral hemorrhage - neurocritical care - hematoma, subdural - hydrocephalus, normal pressure - low back pain - traumatic brain injury - trigeminal neuralgia - adult hydrocephalus - brain concussion - trigeminal neuralgia pain - brain and spine surgery - neurotrauma - sciatica - traumatic spinal cord hemorrhage - intracerebral hemorrhage - normal pressure hydrocephalus - concussion - traumatic spinal injury
Richard Temes, MD
Dr. Richard Temes is a Neurologist with North Shore University Hospital. He is board certified in Neurology
Specialty/ Research Interest - Neurosurgery, Neurology/ Ischemic stroke, subarachnoid hemorrhage, traumatic brain injury, intra cerebral hemorrhage, neurocritical care
David LeDoux, MD
Dr. David LeDoux is a Neuro intensivist with North Shore University Hospital. He is board certified in Internal Medicine and Critical Care Medicine.
Specialty/ Research Interest – Neurocritical care and internal medicine/ sepsis and septic shock, ARDS, intracerebral hemorrhage, SAH, epilepsy.
Tania Rebeiz, MD
Dr. Tania Rebeiz is a Neurologist with North Shore University Hospital. She is board certified in Neurology.
Specialty/ Research Interest – Neurocritical care, neurology, subarachnoid hemorrhage
Michael Schulder, MD
Dr. Michael Schulder is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery
Specialty/ Research Interest - Image guided surgery, intraoperative MRI, brain tumor, outcomes after gamma knife treatments- acoustic neuroma - brain neoplasms - trigeminal neuralgia - brain tumor evaluation - movement disorders and functional neurosurgery - radiosurgery - sterotactic radiosurgery - trigeminal neuralgia pain - functional neurosurgery - image - guided neurosurgery - neurosurgery with intraoperative mri - base of skull structure - brain tumors - skull base
Peter Hollis, MD
Dr. Peter Hollis is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery
Specialty/ Research Interest - brain neoplasms - low back pain - microsurgery - spinal cord diseases - traumatic brain injury - brain tumor evaluation - complex and minimally invasive spine surgery - neurotrauma - skull base disorders in surgery - sciatica - base of skull structure - traumatic spinal cord hemorrhage - spinal disorders - brain tumors - skull base - traumatic spinal injury
Ashesh Mehta, MD
Dr. Ashesh Mehta is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery
Specialty/ Research Interest – Epilepsy surgery, functional brain mapping, functional neurosurgery and neuromodulation -brain neoplasms – epilepsy - hydrocephalus, normal pressure - seizures - traumatic brain injury - brain and spine tumors - brain tumor evaluation - degenerative spine disease - radiosurgery - surgical treatments for epilepsy - functional neurosurgery - neurotrauma - traumatic spinal cord hemorrhage - brain tumors - normal pressure hydrocephalus - traumatic spinal injury
Dr. Mark Eisenberg, MD
Dr. Mark Eisenberg is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurological surgery.
Specialty/ Research Interest – acoustic neuroma - brain neoplasms - hematoma, subdural - hydrocephalus, normal pressure - low back pain - meningioma - pituitary neoplasms - spinal cord diseases - spinal cord neoplasms - chordoma - complex and minimally invasive spine surgery - procedure on spinal cord (procedure) - minimally invasive endoscopic skull base surgery (pituitary and skull base tumors) - endoscopic intracranial and skull base neurosurgery - skull base disorders in surgery - sciatica - base of skull structure - skull base surgery for tumor - skull-base surgery - spinal disorders - brain tumors - meningiomas - normal pressure hydrocephalus - pituitary tumor - skull base - spinal tumors - spine surgery
Athos Patsalides, MD, MPH
Dr. Athos Patsalides is a Neurosurgeon with North Shore University Hospital. He is board certified in Diagnostic Radiology.
Specialty/Research Interest- Minimally Invasive Treatment for Pulsatile Tinnitus- Idiopathic Intracranial Hypertension-Dural Arteriovenous Fistula- Spinal Tumors- Head and Neck Tumors- Ophthalmological Diseases
Thomas Link, MD, MS
Dr. Thomas Link is a Neurosurgeon with North Shore University Hospital. He is board eligible in neurosurgery.
Specialty/Research Interests– subarachnoid hemorrhage – endovascular (interventional) treatment of cerebrovascular disorders – ischemic and hemorrhagic stroke – surgical and endovascular management of subdural hematoma – cerebral aneurysms – cerebral arteriovenous malformations and fistulas – cavernous malformations - neuroprotection in ischemic stroke – carotid and intracranial atherosclerotic disease – traumatic brain injury – brain tumors - endovascular management of head/neck disorders – spinal vascular malformations – trigeminal neuralgia and hemifacial spasm
Amir Dehdashti, MD
Dr. Amir Dehdashti is a Neurosurgeon with North Shore University Hospital. He is board certified in Neurosurgery. Dr. Dehdashti is further trained in cerebrovascular neurosurgery and skull base surgery.
Specialty/Research Interests – intracranial arteriovenous malformation - cerebrovascular disorders - brain aneurysm - Moyamoya disease - acoustic neuroma - Arnold Chiari malformation – subdural hematoma - meningioma - pituitary neoplasms - trigeminal neuralgia - chordoma - skull base neoplasms - carotid endarterectomy - glossopharyngeal neuralgia - hemifacial spasm - Cerebral Cavernous Malformations - Endoscopic endonasal skull base surgery
All investigators and research staff are required to be trained in Good Clinical Practice. This is completed through CITI (www.citiprogram.org ). Our research staff is IATA certified and our research director is a certified research coordinator through the Association of Clinical Research Professionals.
A vast amount of experience in many EDC systems: Medidata Rave, IBM clinical development, eCaseLink, InForm, iMedNet, Axiom Fusion, etc. Research staff is also experienced with using IWRS/IVRS, electronic diaries, and central readers
All new research hires go through internal research training via a fundamentals research class and are able to learn through e-learning modules. They shadow experienced coordinators and are assigned a mentor
Annually, the Department of Neurosurgery sees: 2,000 neurosurgical cases, 14,000 patient visits, 1,100 neuro-interventional cases, 1,100 cranial cases and 900 spinal cases
We have the ability to use central IRBs for our industry-sponsored trials. Our institution has central research support services that we are able to utilize: Office of Clinical Research, Office of Research Compliance, Human Research Protection Program, Clinical Trials Office, and Center for Research Informatics. The CTO manages all clinical trial contracts, budgets and billing. Our office will review, negotiate and complete Confidential Disclosure Agreements (CDAs), sometimes called a Non-Disclosure Agreements (NDAs), Master Clinical Trial Agreements (MCTAs), Clinical Trial Agreements (CTAs), sometimes called Clinical Study Agreements, and Data Use Agreements (DUAs)
Number of studies conducted:
Our site has a low number of lost to follow up and early withdrawal of less than 5%. We follow protocol specific guidelines for data entry and query resolution. We aim to complete data entry 7-10 days after study visit has occurred
––Center for Cerebrovascular and Neuroendovascular Surgery, which offers aneurysm coiling, stent placement, arteriovenous malformation embolization, microneurosurgical aneurysm clipping and cerebral bypass
––Advanced services for the treatment of brain tumors, including stereotactic radiosurgery, intraoperative MRI and minimally invasive surgery
––Comprehensive Epilepsy Program—the first on Long Island to offer laser interstitial thermal therapy and implant the AspireSR device, which delivers vagus nerve stimulation to the brain to predict oncoming seizures
––Neurotrauma services, including minimally invasive treatment for intracerebral hemorrhages, concussions and traumatic brain injuries
–– Surgical and nonsurgical treatments for all spinal conditions
–– Parkinson’s and Movement Disorders Center, which offers the full slate of medical, social and surgical treatments, including deep brain stimulation