Overview

The Rogosin Institute was established in 1983 as an independent, not-for-profit institution for research and health care specializing in kidney disease including chronic kidney failure, diabetic kidney disease, polycystic kidney disease, end stage renal disease and transplantation, and cardiovascular disease due to cholesterol and other lipid disorders, hypertension, diabetes, cancer and sepsis.

The Rogosin Institute is affiliated with New York-Presbyterian Hospital/Weill Cornell Medicine and is a corporate member of New York-Presbyterian Regional Hospital Network. Rogosin Institute members are on the staff of New York-Presbyterian Hospital and have appointments at Weill Cornell Medical College. Several are also on the adjunct faculty at The Rockefeller University.

Research Experience

The Rogosin Institute has been involved in clinical research since its inception in 1983. Phase 1 to 4 studies and investigator-initiated studies are conducted. Our therapeutic interests and clinical trial experience with more than 50 pharmaceutical companies and contract research organizations include:

• End-stage renal disease (ESRD) involving subjects who are on hemodialysis, peritoneal dialysis or home nocturnal hemodialysis
• Polycystic kidney disease 
• Chronic kidney disease (CKD) involving subjects who are predialysis 
• Diabetic kidney disease 
• Hypertension; primary and secondary to kidney disease 
• Kidney and kidney/pancreas transplantations
• Behavioral health
• Cardiovascular disease
• Dyslipidemia disorders
• Hypercholesterolemia
• Familial hypercholesterolemia, including adult and pediatric homozygous and heterozygous familial hypercholesterolemia (HoFH and HeFH)
• Diabetes
• Cancer
• Sepsis

Facility Description

The Rogosin Institute has clinical facilities in Manhattan at New York Presbyterian Hospital/Weill Cornell Medical College as well as in Queens and Brooklyn. The Rogosin Institute offers both outpatient facilities and inpatient facilities. Research facilities are also located in Xenia, Ohio. 

Rogosin Institute outpatient facilities include: 

• Jack J. Dreyfus Clinic, an outpatient facility for the prevention and treatment of kidney disease;
• Susan R. Knafel Polycystic Disease Center, located within the Jack J. Dreyfus Clinic, to diagnose, prevent and treat complications related to polycystic kidney disease;
• Hemodialysis centers located in Manhattan, Queens and Brooklyn;
• David D. Thompson Transplantation Center for kidney transplants and simultaneous pancreas-kidney transplants; and 
• Maurice R. Greenberg Comprehensive Lipid Control Center for prevention and treatment of atherosclerosis and its risk factors for adults and children. 

Rogosin Institute inpatient facilities in New York-Presbyterian Hospital/Weill Cornell Medical College include: 

• The Rogosin Institute Wing for patients requiring hospitalization for kidney disease- related problems and kidney transplantation; and 
• The Rogosin Institute Ralph J. Bunch Dialysis and Apheresis Center for patients undergoing intensive care hemodialysis or LDL-apheresis, which is a specialized treatment for severe genetic hypercholesterolemia. 

Investigator Experience

The investigators at The Rogosin Institute include 23 physicians and four PhDs. The clinical research program offers a clinical research manager, research nurse practitioners and full-time clinical research coordinators.

Bruce R. Gordon, MD
Cholesterol and lipid disorders, plasmapheresis

Dr. Gordon is the director of the clinical research program, executive vice president, and co-director of The Rogosin Institute’s Maurice R. Greenberg Comprehensive Lipid Control Center. He is a professor of clinical medicine and surgery at Weill Cornell Medical College and an attending physician at New York-Presbyterian Hospital. Dr. Gordon has overall responsibility of the clinical research program and has been conducting clinical research for more than 40 years. His research focuses primarily on lipids and cardiovascular research at the Comprehensive Lipid Control Center. 

Betty-Jane Sloan, BS, MA
Certified Clinical Research Coordinator

Ms. Sloan has more than 30 years of experience in clinical research at The Rogosin Institute and is the manager for the clinical research program. Ms. Sloan is a staff associate in the Department of Medicine at Weill Cornell Medical College. 

Irina Barash, MD
Polycystic kidney disease
Nephrology

Nathaniel Berman, MD
Nephrology

Jon Blumenfeld, MD
Polycystic kidney disease
Nephrology
Hypertension

Andrew Bohmart, MD
Nephrology

James Chevalier, MD
Nephrology

Daniel Cukor, PhD
Behavioral health

David Epstein, MD
Nephrology

Dalia Frumkin, MD
Nephrology

Gail Frumkin, MD
Nephrology

Choli Hartono, MD
Nephrology/transplantation

Lisa Hudgins, MD
Lipids/pediatric lipids

Chun Lam, MD
Nephrology

Jun Lee, MD
Nephrology/transplantation

Daniel Levine, PhD
Lipids/biochemistry

Minji Li, MD
Nephrology

Jonathan Lin, MD
Nephrology

Frank Liu, MD
Nephrology
Home hemodialysis

Kotresha Neelakantappa, MD
Nephrology

Leif Oxburgh, PhD
Kidney regenerative medicine

Thomas Parker, PhD
Lipids/biochemistry

Alan Perlman, MD
Nephrology
Diabetic nephropathy

Stuart Saal, MD
Nephrology
Transplantation
Lipids

Jeffrey Silberzweig, MD
Nephrology

Vesh Srivatana, MD
Nephrology
Peritoneal dialysis

Laurence Stam, MD
Nephrology

John Wang, MD, PhD
Nephrology

Staff Expertise

The Rogosin Institute employs a highly trained staff of more than 575 professionals, including physicians, nurse practitioners, registered nurses, social workers, dialysis technicians, phlebotomy technicians, basic and clinical research staff, and registered dietitians. 

Patient Demographics

The Rogosin Institute’s patient facilities are located in New York City, Brooklyn and Queens and include eight dialysis centers. Patients mainly come from the greater New York and tri-state area, which is populated with approximately 20,000,000 people. The Rogosin Institute has access to many diverse nationalities and ages.

Other Information

Institutional Review Boards: The Rogosin Institute can conduct clinical research studies using either central (commercial) IRBs or the local IRBs of Weill Cornell Medical College or The Rockefeller University.

Clinical and Translational Science Centers: The Rogosin Institute has access to Clinical and Translational Science Centers (CTSC) at both New York-Presbyterian Hospital/Weill Cornell Medical College and The Rockefeller University.

Information Technology: The Rogosin Institute employs a full-time database systems manager to provide our investigators with data management for investigator-initiated studies.

Electronic Medical Records: The Rogosin Institute utilizes Allscripts and Darwin electronic medical record systems. These provide immediate access to information on a patient’s history, treatment and laboratory data at all Rogosin Institute facilities and NewYork-Presbyterian Hospital/Weill Cornell Medical College.

Federal-wide Assurance: The Rogosin Institute holds a Federalwide Assurance (FWA 00005225) registered with the Office for Human Research Protection (OHRP).