Overview

The Rogosin Institute was established in 1983 as an independent, not-for-profit institution for research and health care specializing in kidney disease, including chronic kidney failure, diabetic kidney disease, polycystic kidney disease, end stage renal disease and transplantation, and cardiovascular disease due to cholesterol and other lipid disorders, hypertension, diabetes, cancer and sepsis.

The Rogosin Institute is affiliated with NewYork-Presbyterian Hospital-Weill Cornell Medicine and is a corporate member of NewYork-Presbyterian Regional Hospital Network. Rogosin Institute members are on the staff of NewYork-Presbyterian Hospital and have appointments at Weill Cornell Medical College. Several are also on the adjunct faculty at The Rockefeller University

Experience

The Rogosin Institute has been involved in clinical research since its inception in 1983. Phase I – IV studies, as well as investigator initiated studies, are conducted. Our therapeutic interests and clinical trial experience with more than 50 pharmaceutical companies and Contract Research Organizations include:

• End Stage Renal Disease (ESRD) involving subjects who are on hemodialysis, peritoneal dialysis or home nocturnal hemodialysis. 
• Polycystic Kidney Disease 
• Chronic Kidney Disease (CKD) involving subjects who are pre-dialysis 
• Diabetic Kidney Disease 
• Hypertension; primary and secondary to kidney disease 
• Kidney and kidney/pancreas transplantations
• Behavioral Health
• Cardiovascular disease
• Dyslipidemia disorders
• Hypercholesterolemia
• Familial Hypercholesterolemia, including adult and pediatric Homozygous and Heterozygous Familial Hypercholesterolemia (HoFH and HeFH)
• Diabetes
• Cancer
• Sepsis

Facility

The Rogosin Institute has clinical facilities in Manhattan at NewYork-Presbyterian Hospital-Weill Cornell Medical College as well as in Queens and Brooklyn. The Rogosin Institute offers both outpatient facilities and inpatient facilities. Research facilities are also located in Xenia, Ohio. 

Rogosin Institute outpatient facilities include: 

• Jack J. Dreyfus Clinic, an outpatient facility for the prevention and treatment of kidney disease. 
• Susan R. Knafel Polycystic Disease Center, located within the Jack J. Dreyfus Clinic, to diagnose, and to prevent and treat complications related to polycystic kidney disease. 
• Hemodialysis Centers located in Manhattan, Queens and Brooklyn. 
• David D. Thompson Transplantation Center for kidney transplants as well as simultaneous pancreas-kidney transplants. 
• Maurice R. Greenberg Comprehensive Lipid Control Center for prevention and treatment of atherosclerosis and its risk factors for adults and children. 

Rogosin Institute inpatient facilities in NewYork-Presbyterian Hospital-Weill Cornell Medical College include: 

• The Rogosin Institute Wing for patients requiring hospitalization for kidney disease related problems and kidney transplantation. 
• The Rogosin Institute Ralph J. Bunch Dialysis and Apheresis Center for patients undergoing intensive care hemodialysis or LDL-apheresis, which is a specialized treatment for severe genetic hypercholesterolemia. 

Investigators

The investigators at The Rogosin Institute include 23 physicians and four Ph.D’s.  The Clinical Research Program offers a Clinical Research Manager, full time clinical research coordinators, and research nurse practitioners.

Bruce R. Gordon, M.D.
Area of Expertise: Cholesterol and lipid disorders, plasmapheresis

Dr. Gordon is the Director of the Clinical Research Program, Executive Vice President, and Co-Director of The Rogosin Institute’s Maurice R. Greenberg Comprehensive Lipid Control Center. Dr. Gordon is a Professor of Clinical Medicine and Surgery at Weill Cornell Medical College and an Attending Physician at NewYork-Presbyterian Hospital. Dr. Gordon has the overall responsibility of the Clinical Research Program and has been conducting clinical research for more than 40 years. His research focuses primarily on lipids and cardiovascular research at the Comprehensive Lipid Control Center. 

Betty-Jane Sloan, BS, MA, Certified Clinical Research Coordinator
Ms. Sloan has more than 30 years of experience in clinical research at The Rogosin Institute and is the Manager for the Clinical Research Program. Ms. Sloan is a Staff Associate in the Department of Medicine at Weill Cornell Medical College. 

Irina Barash, M.D.
Area of Expertise: Polycystic Kidney Disease/Nephrology

Nathaniel Berman, M.D.
Area of Expertise: Nephrology

Jon Blumenfeld, M.D.
Area of Expertise: Polycystic Kidney Disease/Nephrology/Hypertension

Andrew Bohmart, M.D.
Area of Expertise: Nephrology

James Chevalier, M.D.
Area of Expertise: Nephrology

Daniel Cukor, Ph.D.
Area of Expertise: Behavioral Health

David Epstein, M.D.
Area of Expertise: Nephrology

Dalia Frumkin, M.D.
Area of Expertise: Nephrology

Gail Frumkin, M.D.
Area of Expertise: Nephrology

Choli Hartono, M.D.
Area of Expertise: Nephrology/Transplantation

Lisa Hudgins, M.D.
Area of Expertise: Lipids/Pediatric Lipids

Chun Lam, M.D.
Area of Expertise: Nephrology

Jun Lee, M.D.
Area of Expertise: Nephrology/Transplantation

Daniel Levine, Ph.D.
Area of Expertise: Lipids/Biochemistry

Minji Li, M.D.
Area of Expertise: Nephrology

Jonathan Lin, M.D.
Area of Expertise: Nephrology

Frank Liu, M.D.
Area of Expertise: Nephrology/Home Hemodialysis

Kotresha Neelakantappa, M.D.
Area of Expertise: Nephrology

Leif Oxburgh, Ph.D.
Area of Expertise: Kidney Regenerative Medicine

Thomas Parker, Ph.D.
Area of Expertise: Lipids/Biochemistry

Alan Perlman, M.D.
Area of Expertise: Nephrology/Diabetic Nephropathy

Stuart Saal, M.D.
Area of Expertise: Nephrology/Transplantation/Lipids

Jeffrey Silberzweig, M.D.
Area of Expertise: Nephrology

Vesh Srivatana, M.D.
Area of Expertise: Nephrology/Peritoneal Dialysis

Laurence Stam, M.D.
Area of Expertise: Nephrology

John Wang, M.D., Ph.D.
Area of Expertise: Nephrology

Staff

The Rogosin Institute employs a highly trained staff of more than 575 professionals including physicians, nurse practitioners, registered nurses, social workers, dialysis technicians, phlebotomy technicians, basic and clinical research staff and registered dietitians. 

Patients

The Rogosin Institute’s patient facilities are located in New York City, Brooklyn and Queens and include eight dialysis centers. Patients mainly come from the greater New York and tri-state area, which is populated with approximately 20,000,000 people. The Rogosin Institute has access to many diverse nationalities and ages.

Other

Institutional Review Boards
The Rogosin Institute can conduct clinical research studies using either central (commercial) Institutional Review Boards (IRB) or the local IRB of Weill Cornell Medical College or The Rockefeller University.

Clinical and Translational Science Centers
The Rogosin Institute has access to Clinical and Translational Science Centers (CTSC) at both NewYork-Presbyterian Hospital-Weill Cornell Medical College and The Rockefeller University.

Information Technology
The Rogosin Institute employees a fulltime Database Systems Manager to provide our investigators with data management for investigator initiated studies.

Electronic Medical Records
The Rogosin Institute utilizes Allscripts and Darwin electronic medical record systems.These provide immediate access to information on a patient’s history, treatment and laboratory data at all Rogosin Institute facilities and NewYork-Presbyterian Hospital-Weill Cornell Medical College.

Federal-wide Assurance
The Rogosin Institute holds a Federalwide Assurance (FWA 00005225) registered with the Office for Human Research Protection (OHRP).